50 citations
,
July 2021 in “Nature Communications” This study found that the antiandrogen drug enzalutamide reduced TMPRSS2 levels and significantly decreased SARS-CoV-2 entry and infection in lung cells, supporting further clinical trials for COVID-19 treatment.
34 citations
,
February 1992 in “The Journal of Clinical Endocrinology and Metabolism” In this study, the combination of finasteride and minoxidil significantly increased hair growth in balding male stumptail macaques compared to each drug alone.
33 citations
,
October 2016 in “European Journal of Pharmaceutical Sciences” This study found that a novel effervescent formulation significantly increased minoxidil sulphate accumulation in hair follicles and skin compared to a standard minoxidil solution.
24 citations
,
March 2024 in “Antioxidants” In this review, researchers reported that cinnamon and ginger supplementation may benefit PCOS patients by improving hormonal status, lipid profiles, obesity, and insulin resistance through oxidative stress and inflammation reduction.
13 citations
,
April 2019 in “International journal of molecular sciences” This article reviews the potential of Acyzol, a zinc-containing drug, to treat and prevent zinc deficiency conditions, but it reports no new clinical findings.
12 citations
,
November 2019 in “South African Medical Journal” This study found that the pH levels of relaxers tested were corrosive to the skin and may contribute to alopecia in females with afro-textured hair.
9 citations
,
July 2021 in “Essays in Biochemistry” This review discusses the roles of steroid hormone receptors in lung function related to COVID-19 and outlines ongoing clinical trials of steroid receptor ligands, but reports no new results.
5 citations
,
December 2022 in “Genes” This review discusses the host genetic factors influencing COVID-19 susceptibility and pathogenesis, highlighting genetic variations that affect viral entry and immune responses, but reports no new experimental results.
5 citations
,
December 2022 in “Viruses” This review highlights recent insights into using antiandrogens as preventive and therapeutic measures against COVID-19, emphasizing their role in blocking viral infection by modulating androgen-mediated host protease TMPRSS2 and cell entry protein ACE2, with varying success in clinical trials.
5 citations
,
July 2019 in “Nutrients” This study found that boys in Mexico City with selenium intake below the recommended dietary allowance had lower odds of progressing to advanced stages of pubertal development, while no association was observed in girls.
4 citations
,
July 2023 in “Pharmaceutics (Basel)” This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.
2 citations
,
May 2025 in “Antioxidants” This study examined the phytochemicals and antioxidant activities of methanolic extracts from Cameroonian Prunus africana bark and Leea indica and Paullinia pinnata leaves, identifying various phenolic compounds and significant antioxidant properties through multiple assays.
2 citations
,
January 2025 in “JAAD Case Reports” Topical metformin may improve hair regrowth in CCCA when added to standard treatments.
2 citations
,
September 2020 in “Biomedical materials” This study found that recombinant human hair keratin proteins K31 and K81 show greater potential for inducing skin cell differentiation compared to natural keratin coatings.
May 2026 in “Therapeutic Delivery” This study found that applying a dutasteride-loaded liposome formulation to damp rat skin nearly doubled the drug's follicular accumulation compared to dry skin, suggesting scalp hydration status may significantly impact the drug's topical delivery, especially in follicle-rich areas.
January 2026 in “Journal of Clinical Medicine” This study reviewed literature on the use of robotic systems in plastic and reconstructive surgery, highlighting their application in various procedures despite the predominance of descriptive case reports and a lack of comparative clinical outcomes and long-term data.
December 2025 in “Advanced Healthcare Materials” This study introduces a spherical skin model that effectively mimics key features of human skin, offering a scalable and rapid alternative for non-animal dermatological and cosmetic testing.
November 2024 in “Pharmaceutics” This study found that dutasteride-loaded transfersomes, compared to traditional liposomes, better target hair follicles by releasing the drug in a more controlled manner, as shown in vitro with enhanced follicular targeting (Tf = 0.32 versus 0.15, p < 0.005) using porcine ear skin.
December 2023 in “International Journal of Medical Sciences And Clinical Research” This article discusses trichoscopy as a tool for differential diagnosis in female-type androgenetic alopecia and reports on three patient cases without providing new clinical results.
November 2020 in “Psychoneuroendocrinology” In this study, repeated finasteride administration was associated with decreased social interaction and cognitive deficits in male rats, potentially linked to changes in cholinergic system activity.
June 2024 in “International Journal of Advanced Research in Science Communication and Technology” This study highlights the growing issue of hair loss around the world and explores the potential of using certain herbs, such as Ficus religiosa and coriander seeds, as natural treatments to promote hair growth and manage hair loss, particularly in India, with minimal side effects.
1 citations
,
April 2025 in “Phycology” In this review, researchers highlight recent findings on the cosmeceutical applications of phlorotannins from brown seaweeds, emphasizing their promising bioactive properties since 2020.
2 citations
,
September 2012 in “Asian Journal of Pharmaceutical Analysis” This study developed and validated a second derivative spectrophotometric method for accurately estimating tamsulosin and finasteride in bulk and pharmaceutical formulations.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
42 citations
,
December 2007 in “American Journal of Psychiatry” This study examined finasteride, a 5-alpha-reductase inhibitor, for treating a Tourette’s syndrome patient unresponsive to traditional therapy, noting its limited side effects.
34 citations
,
December 2015 in “Neuroscience & Biobehavioral Reviews” In this study, several compounds, including estrogen and Dutasteride, showed neuroprotective effects on dopaminergic neurons in an MPTP mouse model of Parkinson's disease.
13 citations
,
October 2011 in “Clinical and Experimental Dermatology” This study found no improvement in male-pattern hair loss after six months of using laser hair-comb therapy in two men.
7 citations
,
November 2000 in “Clinics in Dermatology” In this study, pediatric patients with overt polyautoimmunity frequently had systemic lupus erythematosus as an index disease, with clustering patterns revealing familial influence on autoimmune disease aggregation.
September 2020 in “British Journal of Dermatology” This article provides issue information for the September 2020 edition of the British Journal of Dermatology and contains no new research findings.
This review discusses the complex causes and treatment options for female androgenetic alopecia but does not present new research findings, emphasizing the need for early diagnosis and treatment.