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The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

CYP2B12 enzyme in skin cells converts arachidonic acid into specific bioactive lipids.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

DHT, a testosterone byproduct, causes male pattern baldness.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Certain drugs that block specific enzymes can help treat prostate diseases.

Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.

Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Plant steroid hormones show growth, health, and medicinal benefits in various organisms, including potential for treating diseases.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

Germacrone from Curcuma aeruginosa may help treat conditions related to male hormones by blocking a specific enzyme.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.

Adult skin quickly reacts to short-term environmental and internal stress, leading to various skin issues and the need for protective measures.

Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.

Dieckol from Ecklonia cava may help hair growth and could be a potential hair loss treatment.

Puerariae Flos extract may help treat hair loss by blocking a hair loss-related enzyme and promoting hair growth.

Finasteride effectively treats male hair loss, improving growth and density.