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This review discusses the use of ablative and nonablative fractional resurfacing for enhanced topical drug delivery in dermatology and reports no new clinical results; further studies are needed to explore these methods.

This study compared the microscopic treatment zones created by different fractional lasers and radiofrequency in swine skin, finding distinct patterns and damage levels for each technology.

In this study involving 13 patients with vitiligo-associated leukotrichia, minimal hair repigmentation was observed following treatment with fractional CO₂ laser and topical betamethasone, though the method was well tolerated, highlighting the need for further research to optimize treatment parameters.

This source highlights that fractional CO2 laser, as a minimally invasive technology, shows significant benefits in treating various skin and mucosal conditions by improving therapeutic outcomes, shortening recovery times, and enhancing precise personalized interventions through emerging technologies like AI and biomarker monitoring.

In this review, the authors report that fractional resurfacing can be a safe and effective technique for treating scars and promoting photorejuvenation in Asian skin, though it requires cautious use to minimize risks like post-inflammatory hyperpigmentation and rebound melasma.

In this study, the researchers found that the effectiveness of a 1,550-nm fractional laser in promoting hair growth in mice depends on the specific combination of beam energy and density, with inappropriate settings potentially causing ulcers or hair follicle injury.

This study found that combining fractional CO₂ laser with halometasone cream improved chronic eczema more effectively than halometasone alone, with efficacy varying by laser parameters and showing better results at 4 weeks compared to 1 week. Pain was noted with higher energy treatments.

This article contains the late-breaking abstracts from the 39th Annual Conference of the American Society for Laser Medicine and Surgery and does not present new research results.

This review suggests that dermatological cosmetic procedures can be safely performed on dark-complexioned skin with appropriate treatment adjustments, highlighting the need for careful consideration to prevent adverse effects.

This source discusses using stratum corneum ablation as a promising method to enhance transdermal drug delivery by temporarily removing the skin's outermost barrier to improve medication absorption.

This study investigated the effects of 10600nm CO2 dot laser and Nd: YAG laser on Wistar rats' skin, finding that CO2 laser treatment resulted in higher positive expression of MMP-1 and TIMP-1 compared to Nd: YAG laser, with statistically significant differences noted.

This article introduces a special issue of "Lasers in Surgery and Medicine" focused on dermatology and plastic surgery, but it presents no new research findings.

This article discusses various forms of hair loss and their psychological impacts, noting the lack of definitive treatments, but reports no new clinical findings.

This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.

This review outlines the physiological roles of zinc transporters and their involvement in human diseases, emphasizing their molecular, biochemical, and genetic mechanisms without presenting new research findings.

In this first-in-human study, BLZ-100, an intraoperative fluorescent imaging agent, was administered to 21 patients before skin cancer surgery and was found to be well tolerated without serious adverse effects, suggesting its potential to help distinguish cancerous from non-cancerous tissue based on fluorescence.

This study found that scalp care using micro-needle therapy was effective in improving hair density and thickness in middle-aged women with menopausal symptoms compared to a control group.

This study found that acetyl zingerone methyl ether (MAZ) in hair dyes and haircare products may reduce oxidative damage, improve hair condition, and enhance the longevity and quality of dyed hair color.

MPZL3 protein affects hair growth cycles and could help manage hair loss.

This study suggests that MPZL3, a mitochondrially localized protein, may play an integral role in regulating hair follicle cycles, with potential therapeutic implications for hair growth disorders if findings translate to humans.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

This review discusses three classes of thiazole-bearing compounds in drug development and presents preclinical findings but reports no new experimental results, highlighting the need for further drug discovery.

This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.

This study found that MPZL3 plays a crucial role in regulating the hair cycle clock in mice, with its absence leading to accelerated hair follicle cycling and suggesting potential therapeutic pathways for alopecia treatment.

This study found that TPA was significantly more effective than mezerein in inducing dark basal keratinocytes in mouse skin, which may be important in early tumor promotion stages.

This study demonstrated that 5-azacytidine treatment may reduce TSC lesion-related hair follicles in mice, suggesting chromatin remodeling agents could be effective for tuberous sclerosis cutaneous lesions lacking tuberin.

This study shows that ZIP7 is a functional zinc transporter in mammalian cells, facilitating the movement of zinc from the Golgi apparatus to the cytoplasm.

This study reported that ZSYY001, a nanoparticle formulation of polymeric micellar paclitaxel, showed promising antitumor activity and was safe and well-tolerated in preclinical models and a phase I trial, without acute hypersensitivity reactions at doses up to 390 mg/m².

This report discusses a 22-year-old patient with MELAS syndrome carrying the m.10158T>C mutation, and highlights the need for extensive genetic testing when initial hot-spot mutation tests are negative.

This study found that the Transdermal Delivery System efficiently delivers testosterone systemically and showed bioequivalent hormone concentrations to a known topical gel in healthy males.