research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
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research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Successful Response to a Combination of Intralesional Methotrexate and Fractional CO2 Laser in Refractory Alopecia Areata: Case Report
A combination of methotrexate injections and CO2 laser treatment led to complete hair regrowth in two patients with hard-to-treat alopecia.
research Diffuse Partial Woolly Hair in a Patient with Epidermolysis Bullosa Simplex with Mottled Pigmentation
A patient with a rare hair condition and skin disorder showed hair improvement after treatment.
research MiR-27a Targeting PIK3R3 Regulates the Proliferation and Apoptosis of Sheep Hair Follicle Stem Cells
Blocking miR-27a increases sheep hair follicle stem cell growth and decreases cell death, which could help improve wool quality and treat hair loss.
research Antioxidant and Antiproliferative Activity of Finasteride Against Glioblastoma Cells
High-dose finasteride may help treat glioblastoma but needs localized delivery for effectiveness.
research Novel Progestogenic Androgens for Male Contraception: Design, Synthesis, and Activity of C7 Alpha-Substituted Testosterone
New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
research Metallothionein Expression During Wool Follicle Development in Fetal Sheep
Metallothionein likely helps in cell growth and development in wool follicles of fetal sheep.
research More Expression of IL-17 Than IFN-γ from CD49a-Negative Tissue-Resident Memory T Cells at the Hair Bulge and Hair Bulb Region in the Scalp of Chronic Alopecia Areata Patients According to the Foxp3+ mTregs Depletion
IL-17 and certain immune cells are linked to more severe alopecia areata.
research 5% Minoxidil Topical Foam in Women: Menopause and Other Covariates
5% minoxidil foam effectively regrows hair in women, with postmenopausal women seeing the most improvement.
research Cutaneous Adverse Effects of Targeted Therapies
Targeted cancer therapies often cause skin side effects, needing dermatologist care.
research Micro-Current Stimulation Has Potential Effects of Hair Growth Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model
Micro-current stimulation may promote hair growth more effectively than standard treatments.
research A Study on the Clinical Profile and Pharmacogenetics of Methotrexate Treatment in Patients with Rheumatoid Arthritis
The 1298CC genotype in RA patients leads to higher methotrexate toxicity, while the 1298AA genotype results in better treatment response.
research The Reduction of Male Lower Urinary Tract Symptoms Is Associated With a Decreased Risk of Death
Improving symptoms of male urinary problems may lower the risk of death.
research Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study
Once-daily 5% minoxidil foam and twice-daily 2% minoxidil solution are similarly effective and safe for female pattern hair loss.
research Men With an Improvement in Urinary Symptoms Have a Lower Risk of Mortality
Men with better urinary symptoms have a lower risk of death.
research Finasteride Does Not Prevent Bladder Cancer: A Secondary Analysis of the Medical Therapy for Prostatic Symptoms Study
Finasteride does not prevent bladder cancer.
research Mitochondrial DNA Damage, Oxidative Stress, And Atherosclerosis
Improving mitochondrial health may better treat atherosclerosis than antioxidants.
research Efficacy of Topical Diphenylcyclopropenone Maintenance Treatment for Patients with Alopecia Areata: A Retrospective Study
Diphenylcyclopropenone treatment helps prevent hair loss relapse in alopecia areata patients.
research Disease Prevention and Alleviation by Human Myoblast Transplantation
Myoblast transplantation shows promise for treating various muscle and heart conditions.
research The Men's Training Cup Keep Training: A Masturbation Aid Improves Intravaginal Ejaculatory Latency Time and Erection Hardness Score in Patients Unable to Delay Ejaculation
The Men's Training Cup Keep Training masturbation aid may help delay ejaculation and improve erectile function.
research Anticancer Agents Against Malaria: Time to Revisit?
Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.
research Outperforming Ourselves: Invitation for Dialogue
The critique suggests that Wilton's work unintentionally supports the very stereotypes it aims to question and calls for a broader, more inclusive approach to understanding gender.
research Post-Finasteride Syndrome: Real or Imagined?
Finasteride 1mg linked to diverse symptoms; other treatments improve erectile function in rats.
research Association Between Stress and Bilateral Symmetrical Alopecia in Free-Ranging Formosan Macaques in a High-Population-Density Area
Stress likely causes hair loss in Formosan macaques.
research Repositioning Study of Flubendazole for Treating Lung Cancer and Meningoencephalitis Using an Oral Lipid Nanosystem
Flubendazole in a nanoemulsion can potentially treat lung cancer and cryptococcal meningitis effectively and safely.
research Cytotoxic Activity Test of Ethanol and Methanol Extracts of Spirulina Platensis L. on WiDr Cells
Ethanol and methanol extracts of Spirulina platensis do not kill WiDr colon cancer cells.
research Efficacy and Safety of Once-Daily Minoxidil Foam 5% Versus Twice-Daily Minoxidil Solution 2% in Female Pattern Hair Loss: A Phase III, Randomized, Investigator-Blinded Study
Once-daily 5% minoxidil foam increases hair regrowth and density in women with hair loss, but not as effectively as twice-daily 2% minoxidil solution, though it's safer and more convenient.
research Clinical Management of Youth with Gender Dysphoria in Vancouver
Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
research Cross-Sex Hormone Therapy for Gender Dysphoria
Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.