48 citations,
January 2011 in “Hormone Research in Paediatrics” The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.
18 citations,
June 2009 in “Journal of Molecular Endocrinology” Finasteride exposure harms tadpole reproduction and hormone balance.
1 citations,
April 2016 in “Journal of Investigative Dermatology” UV photography can help identify people at higher risk for skin cancer, and male pattern baldness at age 45 is linked to a higher risk of certain skin cancers.
April 2016 in “Journal of Investigative Dermatology” Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.
5 citations,
January 2022 in “Scientific reports” The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
25 citations,
November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
191 citations,
September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
6 citations,
October 2020 in “Journal of Cellular and Molecular Medicine” 3D culture helps maintain hair growth cells better than 2D culture and identifies key genes for potential hair loss treatments.
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
August 2024 in “Cell Death and Disease” Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.
August 2024 in “Nature Communications” Softer hydrogels help wounds heal better with less scarring.
April 2018 in “Journal of Investigative Dermatology” BLZ-100 is safe for use in skin cancer surgery and may help identify cancerous tissue.
April 2018 in “Journal of Investigative Dermatology” High amphiregulin in the skin is a bad sign for acute graft-versus-host disease.
76 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
6 citations,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
April 2018 in “Journal of Investigative Dermatology” Finasteride helps female-pattern hair loss.
25 citations,
October 2018 in “PloS one” Key genes regulate hair follicle phase changes in Inner Mongolia cashmere goats.
118 citations,
October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
124 citations,
September 1992 in “Endocrinology” The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.
182 citations,
August 2016 in “Development” ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.
81 citations,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
6 citations,
February 2022 in “Journal of immunology research” Exosomes from fat-derived stem cells can potentially improve hair growth and could be a new treatment for immune-related hair loss.
48 citations,
November 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.
38 citations,
January 2016 in “Cell Death and Disease” The TCL1 transgenic mouse model is useful for understanding human B-cell leukemia and testing new treatments.
February 2024 in “PloS one” Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.
1 citations,
January 2023 in “Science Advances” The skin's microbiome helps hair regrow by boosting certain cell signals and metabolism.
The KRTAP36-2 gene in sheep affects wool yield.
August 2024 in “Current Issues in Molecular Biology” Key genes and RNAs related to hair growth in sheep were identified, aiding future breeding improvements.
60 citations,
April 2010 in “General and Comparative Endocrinology” Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.
128 citations,
March 2006 in “American Journal of Pathology” Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.