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Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

Hair loss in men is common, treatable, but not curable.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Male pattern baldness involves hormones and cell signals affecting hair growth.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Finasteride effectively treats male hair loss, improving growth and density.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

Finasteride improves hair growth in men with androgenetic alopecia.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

Medicinal plants in Kurdistan have potential health benefits and need more research for drug development.

The herbal hair oil helped hair grow in mice.

Alopecia areata in US adolescents leads to significant healthcare costs and usage.

New guidelines using video aim to ensure honest reporting of hair loss treatments.

A Chinese boy's scalp infection from a guinea pig was cured with medication.

Adolescents with severe alopecia incur significantly higher healthcare costs.