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    Glossary Minoxidil Sulfotransferase

    enzyme activating minoxidil for effective hair growth stimulation

    Minoxidil Sulfotransferase is an enzyme that plays a crucial role in the activation of minoxidil, a common treatment for hair loss. This enzyme converts minoxidil into its active form, minoxidil sulfate, which is more effective in stimulating hair growth. The presence and activity level of this enzyme in hair follicles can influence how well a person responds to minoxidil treatment.

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    1. Purification and characterization of rat liver minoxidil sulphotransferase Biochemical Journal · 1990 · 29 citations
    2. Sulfation of minoxidil by human liver phenol sulfotransferase Biochemical Pharmacology · 1990 · 68 citations
    3. Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles Journal of Investigative Dermatology · 1991 · 46 citations
    4. Food Deprivation-induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis Journal of Biological Chemistry · 2002 · 36 citations
    5. Minoxidil Sulfotransferase Enzyme (SULT1A1) genetic variants predicts response to oral minoxidil treatment for female pattern hair loss Journal of The European Academy of Dermatology and Venereology · 2020 · 7 citations
    6. SULT1A1 (Minoxidil Sulfotransferase) enzyme booster significantly improves response to topical minoxidil for hair regrowth Journal of Cosmetic Dermatology · 2021 · 1 citations
    7. Minoxidil sulfotransferase enzymatical activity in plants: A novel paradigm in increasing minoxidil response in androgenetic alopecia Journal of Cosmetic Dermatology · 2023
    8. Sulfation of minoxidil by liver sulfotransferase Biochemical Pharmacology · 1982 · 66 citations
    9. The effect of topical minoxidil treatment on follicular sulfotransferase enzymatic activity. PubMed · 2019 · 4 citations
    10. Sulfation of minoxidil by multiple human cytosolic sulfotransferases Chemico-Biological Interactions · 1998 · 59 citations
    11. Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil in the treatment of female androgenetic alopecia Dermatologic Therapy · 2014 · 20 citations
    12. Tretinoin enhances minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes Dermatologic Therapy · 2019 · 8 citations
    13. Novel topical booster enhances follicular sulfotransferase activity in patients with androgenetic alopecia: a new strategy to improve minoxidil response Journal of The European Academy of Dermatology and Venereology · 2020 · 3 citations
    14. Characterization of follicular minoxidil sulfotransferase activity in a cohort of pattern hair loss patients from the Indian Subcontinent Dermatologic Therapy · 2018 · 8 citations
    15. Hair follicle sulfotransferase activity and effectiveness of oral minoxidil in androgenetic alopecia Journal of Cosmetic Dermatology · 2024 · 1 citations
    16. Comparison of minoxidil sulfotransferase activity between scalp hair, eyebrows, and eyelashes: Implication for minoxidil efficacy for off‐label use Journal of cosmetic dermatology · 2024
    17. Characterization of Recombinant Human Liver Thermolabile Phenol Sulfotransferase with Minoxidil as the Substrate Biochemical and Biophysical Research Communications · 1995 · 16 citations
    18. Sulfation of minoxidil by human platelet sulfotransferase Clinica Chimica Acta · 1987 · 39 citations
    19. Oral minoxidil bio‐activation by hair follicle outer root sheath cell sulfotransferase enzymes predicts clinical efficacy in female pattern hair loss Journal of The European Academy of Dermatology and Venereology · 2019 · 9 citations
    20. Sulfotransferase activity in plucked hair follicles predicts response to topical minoxidil treatment in Brazilian female pattern hair loss patients Dermatologic Therapy · 2019 · 4 citations
    21. Identification of the sulfotransferase iso-enzyme primarily responsible for the bio-activation of topical minoxidil. PubMed · 2019 · 2 citations
    22. Value of Sulfotransferase Enzyme Assay in Predicting Minoxidil Response in Patients with Androgenetic Alopecia QJM · 2024
    23. Sulfotransferase SULT1A1 activity in hair follicle, a prognostic marker of response to the minoxidil treatment in patients with androgenetic alopecia: a review Postepy Dermatologii I Alergologii · 2020
    24. Microneedling improves minoxidil response in androgenetic alopecia patients by upregulating follicular sulfotransferase enzymes. PubMed · 2020 · 2 citations
    25. Characterization of recombinant human liver dehydroepiandrosterone sulfotransferase with minoxidil as the substrate Biochemical Pharmacology · 1997 · 13 citations
    26. Sulphate conjugation of minoxidil in rat skin Biochemical Pharmacology · 1993 · 9 citations
    27. Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism? Human & Experimental Toxicology · 1996 · 48 citations
    28. Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil Biochemical Pharmacology · 1993 · 53 citations
    29. Minoxidil Sulfation in the Hair Follicle Skin Pharmacology and Physiology · 1994 · 32 citations
    30. Novel enzymatic assay predicts minoxidil response in the treatment of androgenetic alopecia Dermatologic Therapy · 2013 · 27 citations