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Overexpression of a specific receptor in mice skin causes skin thinning, early skin barrier formation, eye issues, and hair loss.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

Balding in men is strongly linked to high blood pressure and family history.

Some oral medications may help treat central serous chorioretinopathy, especially eplerenone, but more research is needed.

New treatments for chronic central serous chorioretinopathy show promise in preventing permanent vision loss.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Spironolactone helps reduce hospital visits and death from heart issues, lowers blood pressure, but has unclear effects on heart failure with normal heart pump function and can cause high potassium and breast enlargement in men.

The patient likely has Chrousos syndrome, a rare condition causing insensitivity to glucocorticoids, requiring high-dose dexamethasone treatment.

Spironolactone may help improve symptoms and tear quality in dry eye disease.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

A patient with congenital adrenal hyperplasia improved after adjusting her medication to prevent Cushing's syndrome symptoms.

New genes and pathways are important for testosterone production and male sexual development.

Spironolactone improved blood vessel function and cholesterol levels in non-obese women with PCOS.

Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.

Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.

Chrousos Syndrome is caused by mutations that make the body less sensitive to glucocorticoids, leading to various symptoms and requiring high-dose treatment.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Pregnant women often experience skin and hair changes, with over half getting stretch marks and pigment changes, and should be cautious with cosmetic procedures due to potential risks.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

The document concludes that diagnosing and treating Congenital Adrenal Hyperplasia is complex and requires a team approach due to its effects on the skin and other symptoms.

Adding licorice gel to laser treatment is more effective for reducing facial hair than laser alone.

Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.

Melatonin and cortisol affect mink winter hair growth, but β-endorphin levels do not.

Androgenetic alopecia is not linked to higher risks of hypertension or hyperaldosteronism.

Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.

A new gene variant causes glucocorticoid resistance in a mother and son.

A dog developed skin issues from too many steroids, but reducing steroids and using a specific treatment fixed the problems.

Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.