Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that in mice with premature ovarian insufficiency, miR-21 enhances ovarian function recovery following umbilical cord-derived mesenchymal stem cell transplantation by influencing specific cellular signaling and immune pathways.

This article proposes using the hallmarks of ageing and dysregulated microRNAs to create a molecular morbidity score that could improve prognostication and clinical trial inclusion for patients with multimorbidity.

This research review highlights the potential of exosome therapy to transform stroke treatment, reporting that in animal models, exosomes can reduce neuroinflammation, oxidative stress, and cell death, while promoting brain repair and regeneration. However, more evidence is needed before clinical applications in humans are established.

This review highlights the potential roles of long non-coding RNAs (lncRNAs) in malignant brain tumors, reporting that further research into their involvement in therapy resistance and cancer pathways could improve diagnosis and treatment outcomes.

This study found that exosomes from human umbilical cord mesenchymal stem cells significantly promoted hair follicle growth and enhanced the transition to the growth phase in a model of androgenetic alopecia, by enriching specific microRNAs that activate key pathways involved in hair regeneration.

This case report describes promising results in treating poliosis circumscripta with exosomes and fractional picosecond laser, showing significant hair regrowth and repigmentation, though spontaneous repigmentation cannot be ruled out.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Higher levels of MiR-92a-1-5p and miR-328-3p found in female hair loss patients.

This review discusses the role of lncRNA Xist in cell growth regulation and disease development, particularly cancer, and reports no new experimental results.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

This review highlights recent advances in understanding how non-coding RNAs, particularly miRNAs and lncRNAs, regulate skin development and homeostasis, but reports no new clinical results.

This study found that the retinoid receptor and PPAR pathway are involved in hair follicle miniaturization in androgenetic alopecia, alongside androgen receptors.

This study observed that exosomes from adipose-derived stem cells promoted hair growth by enhancing dermal papilla cell proliferation and activating signaling pathways, suggesting potential for treating immune-mediated alopecia.

This review highlights that T cells are crucial in regulating hair follicle regeneration and their disruption can lead to alopecia, providing insights into hair disorders related to T cell immune balance and hair follicle regeneration.

In this study, iPSC-derived epidermal organoids demonstrated potential as a novel tool for regenerative medicine by producing high-performance extracellular vesicles that promote proliferation, migration, and angiogenesis in cell-free therapies for wound healing.

This study found that lncRNA H19 may regulate CTGF expression in KGN cells by acting as a "sponge" for miR-19b, potentially influencing polycystic ovary syndrome development.

Certain microRNAs may help treat alopecia areata by targeting immune pathways.

This study suggests that abnormal hair cycles in Hr mutant mice may be caused by HR protein overexpression, which down-regulates miR-31 and increases Tgf-β2 expression.

This study found that vitamin A significantly enhanced the proliferation and inhibited apoptosis of rabbit dermal papilla cells under heat stress, likely by modulating miR-195/IGF1 and Wnt10b/β-catenin signaling pathways.

In this research, lipidomic, proteomic, and metabolomic analyses of exosomes from seven Ashwagandha seed batches revealed that Ashwagandha-derived exosome-like nanovesicles can up-regulate VEGF-A production and promote hair growth in human models tested outside the body.

This study found that exosomes from human umbilical cord mesenchymal stem cells reduced oxidative stress and inflammation in UVB-induced skin injury in cell and mouse models, suggesting their potential for treating UV-damaged skin by influencing Nrf2 and NF-κB pathways.

This review explores recent studies on exosomes for hair loss treatment and reports no new clinical findings, highlighting their potential role as promising agents in hair regeneration.

CBD can help hair grow by supporting scalp health and reducing inflammation.

This study observed that different alkaline buffers had a significant impact on the volume of liquid consumed by fall armyworm larvae, emphasizing the importance of measuring imbibed volumes to reduce dose errors in bioassays.

This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.

In this study, researchers found that the microRNA miR-1199-5p may reduce the expression of SRD5A2 in benign prostatic hyperplasia tissues, potentially contributing to the failure of 5-α reductase inhibitor therapy in some patients.

This review discusses the potential therapeutic effects of exosomes from various cell sources in treating acute kidney injury and explores their mechanisms, but reports no new clinical results.

This review discusses the roles of key epithelial-mesenchymal transition factors and potential therapeutic opportunities involving cancer metabolic pathways, reporting no new clinical results.

This review describes how curcumin, a compound derived from turmeric, affects various cell signaling pathways involved in cancer progression, highlighting its potential as a therapeutic agent with fewer side effects compared to conventional cancer treatments.

In this study, researchers identified key transcriptome changes in male androgenetic alopecia hair follicles, suggesting that HIF-1 pathway genes and Wnt pathway inhibitors could be potential therapeutic targets.