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This review paper highlights that titanium dioxide nanoparticles (TiO2 NPs), due to their biological properties like antioxidant, anti-inflammatory, and antimicrobial effects, show promise in accelerating wound healing and enhancing tissue regeneration when used in scaffolds and dressings.

This study observed that six sessions of injections using a stabilized hyaluronic acid compound improved hair thickness, shine, density, and reduced hair loss in volunteers with moderate androgenetic alopecia, with excellent treatment tolerability and high satisfaction reported by 88.5% of participants.

This article explores the potential applications of polyglutamic acid in cosmetics, discussing its benefits for skincare and haircare, but reports no new experimental results.

In a mouse model study, transcutaneous auricular vagus nerve stimulation (taVNS) significantly reduced depigmentation in vitiligo, potentially through mechanisms that regulate oxidative stress and inflammation, indicating taVNS's promise as a therapeutic approach for this skin disorder.

This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.

This review highlights the importance of apoptosis in the hair cycle, particularly its role in hair follicle regression and loss, suggesting that understanding its mechanisms can aid in developing treatments to reduce hair loss and promote hair growth.

This study found that supercritical fluid extraction of germinated perilla seed significantly promoted hair follicle cell proliferation and gene expression related to hair growth, suggesting its potential as a natural treatment for hair loss.

This review discusses completed and ongoing clinical studies on microneedle-based technologies for cosmetic, therapeutic, and diagnostic applications and reports no new clinical results.

This study found that repeated microneedle stimulation in mice promoted hair growth and increased the expression of hair-growth-related genes, suggesting potential therapeutic uses for alopecia.

This article reviews the applications of microneedle technology in drug delivery, dermatology, and cosmetics, but it presents no new experimental or clinical findings.

This pilot study suggests that using growth factors followed by microneedle therapy may benefit women with female pattern hair loss.

This study found that photodynamic therapy with methyl 5-aminolevulinic acid was ineffective for treating alopecia totalis, even with microneedle rolling to enhance drug delivery.

This study found that a newly created biomimetic microneedle platform effectively expedited wound repair in diabetic animal models by reducing inflammation, enhancing angiogenesis, and promoting skin regeneration through targeted drug delivery and immune response modification.

This study found that combining micro-needling, low-level laser therapy, and autologous non-activated platelet-rich plasma increased hair density in patients with androgenic alopecia over the treatment period.

In this study, researchers found that dissolving microneedles made with hyaluronic acid enhanced the effectiveness of minoxidil in reducing hair loss and promoting hair growth in alopecia-affected mice more effectively than topical minoxidil alone, while using only 10% of the drug amount.

In this study, a home-use microneedle device combined with 5% minoxidil showed potential for enhancing hair growth in pattern hair loss over six months, although the observed improvements in hair count and patient assessments were not statistically significant compared to other treatments.

This study found that HRHDT combined with microneedle therapy improved hair growth in a mouse model of alopecia more effectively than microneedle therapy alone.

In this study, the combination of ECM-C with microneedle and radiofrequency treatments improved periorbital wrinkles, skin elasticity, and thickness more effectively than ECM-C with microneedles alone, but subjective evaluations showed no significant differences.

In this study, combining microneedle and sublative fractional radiofrequency treatments significantly improved skin tightening, texture, collagen organization, and satisfaction in individuals with moderate photoaging, while reducing abnormal elastin after three months.

This study reports that the microneedle therapy system has demonstrated significant effects on acne, acne scars, and hair loss treatment without serious side effects in Korean studies over the past decade.

In this study, Ganoderma lucidum extract combined with microneedle therapy promoted hair growth more effectively than microneedle therapy alone in a mouse model of alopecia.

This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.

This study found that a microneedle patch containing tofacitinib-loaded nanoparticles significantly increased hair follicle numbers and promoted hair regeneration with less drug compared to daily topical tofacitinib, suggesting it may be an effective strategy for alopecia treatment by reducing dosing frequency and enhancing drug delivery.

This study found that micro needle roller therapy enhanced hair follicle development and increased growth factor expression in C57BL/6 mice, suggesting potential benefits for alopecia treatment.

This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.

This study found that a transdermal drug delivery system using nanostructured lipid carriers and polymeric microneedles for β-sitosterol significantly enhanced hair growth in testosterone-induced alopecia rats, suggesting potential for treating androgenic alopecia.

In this study, researchers developed a nanocomposite microneedle patch containing copper/zinc dual-doped silica nanoparticles, which release substances to promote hair follicle regeneration by targeting various pathophysiological aspects of androgenic alopecia, presenting an effective anti-hair loss treatment strategy.

This review reports that microneedle systems can enhance the delivery and effectiveness of Traditional Chinese Medicine compounds in treating skin disorders, though most findings are based on preclinical studies and face challenges in translating to clinical practice.

This study found that using a palmitoylated peptide, Pal-MPAPO, delivered through hydrogel microneedles effectively promoted hair regrowth in mice with efficacy comparable to minoxidil, while requiring less frequent application.

In this study, microneedle-assisted delivery of polyglutamate significantly improved hair parameters, scalp symptoms, and quality of life in androgenetic alopecia patients, with no serious adverse reactions reported.