Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that finasteride microemulsions significantly increased skin permeability in vitro, highlighting the potential for enhanced delivery of this drug through the skin.

This review summarizes the positive clinical response of using platelet-rich plasma as an adjuvant in skin rejuvenation treatments, with no identifiable complications, suggesting a promising outlook for its future use.

This study found that UVB radiation significantly alters miRNA expression and induces cytotoxicity and apoptosis in normal human dermal papilla cells.

This study found that metyrapone and etomidate provide dose-dependent anticonvulsant effects against seizures, with delayed effectiveness linked to increased neurosteroid levels.

This case report describes a 5-year-old girl with an extensive Microsporum canis scalp infection, highlighting griseofulvin as the preferred treatment and noting corticosteroids' benefit in severe inflammatory cases.

In this study, a multifunctional microneedle patch made from silk fibroin-methacryloyl and gelatin methacryloyl was reported to significantly prevent bacterial infection and promote wound healing in vivo due to its antimicrobial silver nanoparticles and VEGF-loaded tips.

This review highlights the potential of microneedles for immunotherapy, emphasizing their ability to enhance immune responses and reduce side effects through precise and stimuli-responsive delivery, especially in tumor treatment, while also noting the limitations and areas for improvement in current systems.

This study explores the use of bioinspired 3D printed hollow microneedles, which may offer improved delivery of anti-wrinkle formulations, and reviews the current landscape and challenges of existing wrinkle treatments and microneedle technology.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This study reports that different animal species exhibit distinct hair scale patterns and elemental compositions, which can aid forensic investigations in identifying animal hair.

This review found that microneedling is generally safe, with most adverse effects being minor and resolving quickly, though there is increased risk in patients with active infections, darker skin, or metal allergies.

FUE hair transplantation using a micromotor is effective and gives natural results with few complications.

This case report details a 10-year-old boy diagnosed with kerion celsi caused by Microsporum gypseum, successfully treated with itraconazole over 4.5 months.

This report describes a case of adrenomyeloneuropathy where neurogenic bladder dysfunction developed, attributed to demyelinating lesions in the patient's peripheral nerves, spinal cord, and cerebral white matter.

This study observed that daily selenium sulfide shampoos successfully removed fungal spores hidden beneath the hair cuticle in patients infected with ectothrix Microsporum canis.

This study found that micro-needling combined with topical 5-fluorouracil (5-FU) was more effective in treating vitiligo patches than topical tacrolimus, with significant improvement observed in six patients, although it caused mild side effects like erythema and irritation.

This study demonstrated that customized microneedle arrays can precisely induce targeted hair regeneration and improve hair quality in mice, potentially offering a personalized treatment approach for hair loss.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This study explored the use of "microfollicles," a human hair follicle organoid model, as an in vitro tool for testing hair-growth substances, finding up to 75% overlap in gene expression changes with human clinical biopsy responses to minoxidil, indicating its potential for pre-clinical substance testing.

This study found that the retinol dehydrogenases SDR16C5 and SDR16C6 in mice play a crucial role in skin retinol dehydrogenase activity, affecting hair growth and gland functions without impacting survival.

The researchers reported that miR-21 expression increases with age in both human and mouse skin and may contribute to skin aging by targeting the chromatin remodeler SATB1 in keratinocytes.

This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.

This study suggests that epigallocatechin gallate (EGCG) from green tea may counteract DHT-induced hair follicle damage by modifying the miRNA expression profile in human dermal papilla cells.

This study reported that combining microdialysis and selective follicular closure with varnish significantly reduces caffeine penetration through hair follicles in an ex vivo porcine ear skin model.

This study identified specific miRNAs that are potentially linked to severe active alopecia areata, suggesting they could be targets for future treatment development.

This study suggests that erlotinib exacerbates inflammation in a mouse model of skin disease and that IL-1 inhibition could mitigate skin-related side effects of EGFR inhibitors.

This study found that levels of the protein MAGP-1, important for skin elasticity, decrease with aging and photoexposure, potentially contributing to skin fragility, sagging, and enlarged pores.

This study identified specific miRNAs and mRNAs involved in the development of secondary hair follicles in cashmere goats, particularly noting a targeted relationship between chi-miR-30e-5p and DLL4.

This study found that mice lacking myelin protein zero-like 3 (Mpzl3) had reduced body weight and adiposity despite increased food intake, which was linked to higher energy expenditure and improved glycemic control.

This review highlights the promising potential of microemulsions and nanoemulsions in (trans)dermal drug delivery, noting a gap in understanding their distinct mechanisms and composition-related effects on skin permeability, while emphasizing the limited clarity on mesostructures and cosolvent impacts.