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In this study, the SAFE System for follicular unit extraction demonstrated a favorable average follicle transection rate of 6.14% and is accessible for physicians with basic technical skills, showing promise for wider adoption.

This study found that the SAFE System may improve follicular unit extraction by reducing follicle transection rates and broadening patient eligibility, with only minor adverse reactions reported.

This study found evidence of increased DNA methylation of the androgen receptor gene in occipital hair follicles from men with androgenetic alopecia.

This study in cashmere goats found that DNA methylation levels were lower during hair follicle differentiation compared to induction, suggesting it plays a critical role in gene regulation for hair morphogenesis.

This study found that pretreating mouse skin with microneedles significantly enhanced the hair growth inhibitory effect of eflornithine cream, likely by improving its skin permeation.

This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.

Accurate method measures finasteride levels in human plasma using gas chromatography-mass spectrometry.

This study found that DNA hypermethylation was present in melasma lesions, and treatments with sunscreen, niacinamide, and retinoic acid were associated with decreased methylation and clinical improvement.

This study found that valproic acid may interfere with the leucine metabolic pathway by inhibiting 3-methylcrotonyl-CoA carboxylase and biotinidase, which could contribute to side effects like skin rash and hair loss in patients.

This study characterized human Wharton's Jelly Mesenchymal Stem Cells (hWJ-MSCs) isolated from umbilical cords using explant and enzymatic methods, finding both methods yielded high-purity cells capable of differentiating into adipocyte, chondrocyte, and osteocyte lineages, showing promise for regenerative medicine applications.

This study observed that electro-acupuncture reduced global DNA methylation and DNMT3b expression in a PCOS-like rat model, suggesting a role of hypothalamic DNA methylation in PCOS development and treatment.

Oral minoxidil effectively controls blood pressure quickly and safely.

The authors concluded that utilizing clock gene expression from hair follicle cells may improve circadian-phase estimation in clinical settings, aiding the detection of circadian-related sleep problems despite social time constraints.

This study found that S-Methylmethionine sulfonium (SMMS) enhances cell survival and reduces damage from UVB irradiation in skin cells, suggesting its potential as a cosmetic ingredient for UV protection.

This research discusses a validated HPTLC method for simultaneously determining Tamsulosin Hydrochloride and Finasteride in bulk and pharmaceutical dosage forms but reports no new clinical results.

This study found that MENT is 10 times more potent than testosterone in suppressing gonadotropins and contributing to anabolism in monkeys, with a potentially wider therapeutic index for human androgen replacement and male contraception.

This study found that the spermidine analog N1-methylspermidine prolonged hair follicle growth and decreased inflammation and oxidative stress in cultured hair follicles, suggesting potential relevance for treating inflammatory scalp diseases.

This study developed a method using LC/APCI-MS to measure the activity of steroid 5α-reductase, applied to kinetic studies and inhibitory tests with Finasteride in a rat prostatic enzyme model.

In this study, topical application of α-methylspermidine during the telogen phase in mice induced hair growth by increasing the polyamine pool and mimicking the anagen phase's characteristics.

This study developed and validated a method using hair samples to simultaneously detect bisphenols and parabens, enabling the quantification of these endocrine disruptors in a hospital population’s hair.

This study found that phototoxic psoralen and ultraviolet A therapy with topical 8-MOP was effective in treating alopecia areata resistant to other treatments, improving hair regrowth with minimal side effects.

Low m6Ascores in melanoma predict better survival and response to immunotherapy.

This study reports that a single transplantation of autologous stromal vascular fraction significantly increased hair density and keratin score in androgenic alopecia patients within six months.

This study explored the development of GelMet, an electrospun hybrid nanofiber scaffold made from gelatin and PEG methacrylate, which demonstrated strong mechanical properties and effectively supported cell growth in vitro, suggesting its potential for skin tissue engineering applications.

This study found that using a hair removal laser can effectively reduce hair thickness in the hairline of Asian women with thick donor hairs from previous hair transplants, improving hairline appearance with mild, transient side effects.

This study demonstrated that mink hair growth and pelt quality significantly depend on dietary protein levels and DL-methionine supplementation during the growing-furring period.

Validated method reliably measures finasteride in tablets using liquid chromatography.

This study found that using a novel dissolving microneedle with valproic acid effectively enhances hair follicle regrowth through improved delivery and activation of the Wnt/β-catenin pathway compared to topical application.

This study found that the methylation level of the IGFBP4 promoter is negatively correlated with mRNA expression and may serve as an epigenetic marker for wool fineness in Super Merino sheep.

This study identified key genes and pathways related to wool follicle development in coarse wool lambs, suggesting epigenetic factors may influence wool sheep domestication and breeding.