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    Did you mean Metabotropic Receptor?
    Glossary Metabotropic Receptor

    cell receptor triggering internal signaling via G-protein activation

    A metabotropic receptor is a type of cell surface receptor that, when activated by a neurotransmitter, initiates a cascade of intracellular events through a signaling molecule called a G-protein. Unlike ionotropic receptors, which form ion channels, metabotropic receptors work indirectly to modulate cellular activity, often resulting in longer-lasting and more diverse effects.

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    Research 30 of 73

    1. The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2 Experimental physiology · 2023 · 6 citations
    2. Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth EMBO journal · 2018 · 34 citations
    3. Modulating mechanosensory afferent excitability by an atypical mGluR Journal of anatomy · 2015 · 1 citations
    4. Synaptic‐like vesicles and candidate transduction channels in mechanosensory terminals Journal of Anatomy · 2015 · 11 citations
    5. Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol 2018
    6. Relating neurosteroid modulation of inhibitory neurotransmission to behaviour Journal of Neuroendocrinology · 2021 · 18 citations
    7. Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals PLoS ONE · 2013 · 25 citations
    8. Neurosteroids, neuroactive steroids, and symptoms of affective disorders Pharmacology, Biochemistry and Behavior · 2006 · 82 citations
    9. The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors Drug Metabolism Reviews · 2006 · 219 citations
    10. Immunohistochemical expressions of mGluR5, P2Y2 receptor, PLC-?1, and IP3R-I and -II in Merkel cells in rat sinus hair follicles Histochemistry and Cell Biology · 2003 · 32 citations
    11. Transient Ca2+ entry by plasmalogen-mediated activation of receptor potential cation channel promotes AMPK activity Frontiers in molecular biosciences · 2022 · 3 citations
    12. Calcium regulation of stem cells EMBO reports · 2020 · 25 citations
    13. mTORC1 activity negatively regulates human hair follicle growth and pigmentation EMBO reports · 2023 · 12 citations
    14. TRP Channels in Skin Biology and Pathophysiology Pharmaceuticals · 2016 · 124 citations
    15. γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress Life sciences · 2023 · 1 citations
    16. The RAIG Family Member, GPRC5D, Is Associated with Hard-Keratinized Structures 2004 · 64 citations
    17. Glutamic acid promotes hair growth in mice Scientific Reports · 2021 · 12 citations
    18. Unravelling a novel role for cannabidivarin in the modulation of subventricular zone postnatal neurogenesis European Journal of Pharmacology · 2023 · 7 citations
    19. Poster Abstracts Fundamental & Clinical Pharmacology · 2017
    20. Pre-clinical non-viral vectors exploited for<i>in vivo</i>CRISPR/Cas9 gene editing: an overview Biomaterials Science · 2022 · 23 citations
    21. Sights for Sore Eyes and Disappointments in Psychopharmacology Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology · 2014 · 3 citations
    22. Ethanol extract of asiasari radix preferentially induces apoptosis in G361 human melanoma cells by differential regulation of p53 BMC Complementary and Alternative Medicine · 2019 · 2 citations
    23. Photo-downregulation of SIRT4 mitigates aging in mice by enhancing H3K9ac via fatty acid metabolism bioRxiv (Cold Spring Harbor Laboratory) · 2026
    24. Local synthesis and function of neuro-estrogen and neuro-androgen: impact on the hippocampus-related cognition and neuronal plasticity Frontiers in Cellular Neuroscience · 2026
    25. The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review Frontiers in Immunology · 2025
    26. Effect of neurosteroid dehydroepiandrosterone on the higher nervous activity of old non-human primates Human Physiology · 2014
    27. A Cell Membrane-Level Approach to Cicatricial Alopecia Management: Is Caveolin-1 a Viable Therapeutic Target in Frontal Fibrosing Alopecia? Biomedicines · 2021 · 4 citations
    28. AVALIAÇÃO DO USO DE TELAS DIGITAIS POR CRIANÇAS E ADOLESCENTES EM TEMPOS DE PANDEMIA Brazilian Journals Editora eBooks · 2023 · 1 citations
    29. Rab5c-mediated endocytic trafficking regulates hematopoietic stem and progenitor cell development via Notch and AKT signaling PLoS Biology · 2020 · 32 citations
    30. Combined drug triads for synergic neuroprotection in retinal degeneration Biomedicine & pharmacotherapy · 2022 · 6 citations