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The skin is the largest organ, protecting the body, regulating temperature, and producing hormones.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.

Rosacea is a skin condition with unclear causes, classified into four subtypes.

The European Society of Cutaneous Lupus Erythematosus created a questionnaire to standardize patient assessment and improve care for cutaneous lupus.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

CD4+ skin cells may be precursors to basal cell carcinoma.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Hair and nails can help diagnose diseases, with nail issues often linked to skin conditions and hair loss having various causes and treatments.

Different hair and nail conditions can indicate health issues and have specific treatments; accurate diagnosis is crucial before treatment.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Hair loss that spreads out can often fix itself or be treated by finding and handling the cause.

The document concludes that there are various treatments for different types of alopecia, but more research is needed for evidence-based treatments.

Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.

Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.

Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.

Some drugs can cause skin reactions, which may improve when the drug is stopped, and rapid diagnosis and stopping the drug is crucial.

Cooling the scalp may prevent hair loss from chemotherapy, hair often grows back after treatment, and nail issues usually improve after stopping the drug.

A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.

Fractional CO2 laser is more effective and safer than steroid injections for treating alopecia areata.

Liposomes could improve how skin care products work but are costly and not very stable.

Early diagnosis and treatment of discoid lupus erythematosus improve outcomes.

Tattooing helps treat skin conditions, reconstruct nipple-areola, mark radiation fields, and locate lesions.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

Hair problems are common and distressing for women, but increasing knowledge of treatments offers hope.

Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.