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This study found that women with PCOS, especially those who are obese, showed higher oxidative stress and decreased antioxidant levels, correlating with metabolic syndrome and cardiovascular disease risk factors.

This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.

This study found that resveratrol significantly alleviated testicular damage in male rats caused by finasteride, which otherwise led to decreased testosterone levels and various histopathological alterations in the testes.

In this study, selenium-rich diets enhanced antioxidant activity in aged mice, suggesting potential biological benefits, although further trials are needed to fully understand long-term risks and benefits.

Oxidative stress plays a role in female pattern baldness, causing an imbalance between harmful and protective elements in the body.

This study found that Adiantum capillus-veneris extract exhibited significant antidepressant and anti-anxiety effects in rats, likely due to its antioxidant and anti-inflammatory properties.

This study suggests that hair follicle mesenchymal stem cells may alleviate small intestinal ischemia-reperfusion injury in rats by promoting angiogenesis, reducing apoptosis, and enhancing intestinal stem cell expression.

In a study on mice, cow placenta extract showed strong antioxidant activities and reduced collagen damage, suggesting it could help delay skin aging caused by D-galactose.

This study reports that γ-ray exposure in rats led to dermal endothelial proliferation, new vessel formation around hair follicles, and increased inflammatory markers, suggesting possible early stimulatory effects on hair growth.

The researchers reported that corticosteroid treatments for alopecia areata led to clinical improvement but did not significantly alter oxidative stress markers, suggesting a limited regulatory effect on these systems.

This study found that bergamot and boxthorn extract significantly improved skin antioxidant activity and collagen content while promoting hair growth in mice.

This study found that an 8-week supplementation with specific probiotic strains improved hormonal markers and oxidative stress while decreasing inflammation in women with PCOS, although clinical symptoms like acne and hirsutism showed no significant improvement compared to the placebo group.

This preliminary study found that Melandrium firmum extract may promote hair growth and inhibit 5α-reductase, suggesting potential as a candidate for treating androgenetic alopecia.

This study found that Zhuangyao Jianshen pill significantly improved prostate health in testosterone-induced benign prostatic hyperplasia in castrated rats by modulating sex hormones and reducing inflammation and oxidative stress.

In this study with hair-loss-induced rats, topical minoxidil treatment was found to have antioxidant effects in the skin and blood, decreasing oxidative stress markers over a 21-day period, without showing significant hair growth improvement compared to the control group.

This study identified a small population of PAX3+/CD34+ cells in human foreskin tissue that may serve as transition cells between melanocyte stem cells and hair follicle stem cells, characterized by specific marker expressions.

This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.

This letter to the editor shares a case study of lentiginous melanoma that appears clinically malignant but histopathologically benign, involving the BRAFV600R mutation.

This study found that Ganoderma lucidum fruiting body powder improved cholesterol profiles and hair follicle health in rats exposed to a tumor-promoting agent, suggesting potential chemopreventive properties against skin abnormalities.

In this clinical study, melatonin treatment reduced oxidative stress markers and enhanced hair growth in patients with alopecia areata, potentially through its effects on the immune system and antioxidant activity.

This study found that Eucommia ulmoides bark extract shows potential antioxidant and hair follicle-support properties in vitro and in vivo, but further validation is needed to confirm these effects.

This narrative review found a strong association between oxidative stress and the severity of alopecia areata, noting that increased oxidant and reduced antioxidant biomarkers correlate with higher disease severity scores, and emphasizes the need for larger prospective studies for clinical validation.

This review synthesizes findings from 15 animal studies on alopecia, identifying key biomarkers like TNF-α and IL-6 that suggest inflammation and follicular damage, offering insights into potential targeted therapies to balance degenerative and regenerative pathways for more effective treatment strategies.

This study found that both acute and chronic exposure to nano polystyrene in laboratory rats disrupted hematological function, increased oxidative stress, and led to behavioral and physiological changes, like anemia-like effects and neurological disruptions, suggesting its potential as a cumulative toxicant.

This study found that ursolic acid at 50 mg/kg improved biochemical, hormonal, and ovarian histopathological markers in a rat model of PCOS, suggesting its potential as a therapeutic option.

In this study, oral administration of wheat sprout extract significantly protected rats against skin damage caused by acrylamide exposure by enhancing antioxidant defenses, reducing oxidative stress, and preserving skin structure, highlighting its potential as a sustainable protective agent against environmental skin toxins.

In this study, orally administered Centella asiatica extract, standardized for asiaticoside content, significantly improved skin barrier function, elasticity, and reduced signs of UVB-induced photoaging in hairless mice, highlighting its potential as a nutricosmetic for skin health.

This study found that administering lycopene to rats provided significant protection against the testicular damage caused by finasteride, as indicated by improved sperm parameters, and reduced oxidative stress and apoptosis markers.

In this study, isotretinoin, an effective treatment for severe acne, was found to significantly impact hematological, inflammatory, and oxidative stress biomarkers, suggesting potential risks alongside its therapeutic benefits.

This study found that children with alopecia areata had higher levels of oxidative stress markers but showed no significant differences in depression and suicide tendencies compared to healthy peers.