240 citations,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
127 citations,
November 2010 in “Pigment cell & melanoma research” We need more research on human hair follicle pigmentation, not just mouse models.
41 citations,
January 2006 in “Dermatology” Noncultured epidermal cell transplantation is effective for repigmenting stable vitiligo.
26 citations,
June 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Regenerative therapies show promise for treating vitiligo and alopecia areata.
23 citations,
March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
21 citations,
January 2019 in “Experimental dermatology” Light therapy using helium-neon lasers can help restore skin color in vitiligo by promoting skin cell growth and movement.
18 citations,
March 2015 in “Journal of Investigative Dermatology” Silencing certain circadian clock genes increases skin pigmentation.
11 citations,
September 2013 in “Journal of The European Academy of Dermatology and Venereology” People with alopecia areata may be more likely to have a certain type of hearing loss.
6 citations,
January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Gray hair regained color after thyroid hormone treatment.
5 citations,
July 2019 in “Clinical and experimental dermatology” Adding collagenase to trypsin improves cell yield and repigmentation in vitiligo treatment.
4 citations,
October 2021 in “International Journal of Cosmetic Science” Cirsium japonicum flower extract increases melanin production and could help treat depigmentation conditions.
3 citations,
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
2 citations,
May 2018 in “Australasian Journal of Dermatology” Some patients' hair grew back black and white after chemotherapy.
1 citations,
September 2018 in “International journal of research - granthaalayah” Human hair medulla doesn't break down hydrogen peroxide, which may affect hair color formation.
1 citations,
December 2015 in “Journal of the Medical Sciences (Berkala Ilmu Kedokteran)” Transplanting melanocyte stem cells from hair follicles can effectively treat vitiligo.
The human scalp has different types of pigment cells in hair follicles with varying abilities to produce pigment.
January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.
November 2021 in “CRC Press eBooks” Hair color is determined by melanin and can be affected by genetic conditions like albinism.
May 2021 in “International journal of developmental research” Estrogens and progesterone are key in regulating melasma pigmentation.
Melanin-rich skin has unique challenges in diagnosing and treating skin diseases.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a new way UVB light increases skin pigmentation through the ATP-P2X7 pathway.
January 2006 in “Yearbook of Dermatology and Dermatologic Surgery” Hair graying is caused by the loss of pigment cells due to poor maintenance of stem cells in the hair follicle.
September 1998 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that individualized treatments for hair issues are effective, certain hair changes can indicate neurocutaneous diseases, specific lotions improve skin health, laser hair removal works but needs more study on long-term effects, men's cosmetics are diverse, peeling is effective but can have side effects, and facial pigmentation is often due to overactive skin cells.
58 citations,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
47 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
30 citations,
December 2001 in “Experimental dermatology” Gonadal hormones significantly affect the severity of alopecia areata in mice.
23 citations,
March 2017 in “PTR. Phytotherapy research/Phytotherapy research” Butin is effective in treating vitiligo in mice.
13 citations,
January 1993 in “Archives of dermatological research” Human hair follicles can grow and stay healthy for up to 8 days in a lab setting.
8 citations,
June 2016 in “Journal of Cutaneous Pathology” Two women were diagnosed with a rare melanoma that looked like hair loss but was actually a type of skin cancer.
3 citations,
December 2016 in “Journal of epidemiological research” Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.