research Life of the B10 Mouse: A View from the Hair Follicles and Tissue Stem Cells
Mouse skin and hair aging starts at 200 days, with changes in hair follicles and more white hairs as signs of aging.
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research The Multiple Uses of Azelaic Acid in Dermatology: Mechanism of Action, Preparations, and Potential Therapeutic Applications
Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
research A Preliminary Study of Melanogenic Markers in the Differentiation of the Human Hair Follicle Melanin Unit
The study found markers indicating that cells responsible for hair color are differentiating in specific areas of the hair follicle.
research Varicella-Zoster Virus in Actively Spreading Segmental Vitiligo Skin
The study suggests a link between varicella-zoster virus and segmental vitiligo, with evidence of the virus disrupting skin pigment cells.
research Dynein Is Involved in the Movement, Distribution, Acidity, and Transfer of Melanosomes
Dynlt3 is important for melanosome transport and skin coloration.
research Nutrient and Stress Sensing as Novel Physiological Regulator of Human Hair Pigmentation and Greying: Role of mTORC1 Activity
Blocking mTORC1 activity could increase hair pigmentation and potentially reverse greying.
research Melatonin: A Cutaneous Perspective
Melatonin is good for skin health and may help treat skin conditions.
research Evaluation of E-Cadherin and Hydrogen Peroxide in Skin of Patients with Vitiligo
Vitiligo patients have higher hydrogen peroxide levels and lower E-cadherin, affecting skin cell adhesion and pigmentation.
research Photosensory Function, Reception, and Response in Human Skin
Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
research A New 3D Skin Model Containing Autologous Immune Cells Reconstructed by Tissue Engineering
Researchers developed a 3D skin model with its own immune and blood vessel cells to better understand skin health and disease.
research Single Cell Transcriptome Profiling of Human Interfollicular Epidermis Reveals Robust Heterogeneity and Divergent Differentiation Lineages
The human skin's outer layer has more variety in cell types and development paths than previously thought.
research Development of an Ex Vivo Human Skin Explant Model to Examine Candidate Gene Functions in the Hair Follicle and Epidermis
The model can effectively test gene functions and drug responses in human skin.
research Surgical Treatments of Leukodermas Other Than Vitiligo Vulgaris
Hair transplantation showed the most promise for repigmenting white hair, especially for eyebrows and eyelashes.
research Transgenic Endothelin 3 Regulates Murine Pigment Production and Coat Color
The gene Endothelin 3 makes mice's fur darker by increasing pigment cells and pigment levels.
research Age-Induced Hair Graying and Oxidative Stress
Gray hair is caused by oxidative stress damaging hair cells.
research BMP Signaling in the Hair Follicle Stem Cell Niche Regulates Hair Growth and Skin Pigmentation
BMP signaling controls hair growth and skin color.
research In Vitro Culturing and Harvesting of Human Plucked Hair Follicles
Growing hair cells in the lab from plucked hairs could lead to a new, less invasive, and cheaper baldness treatment.
research Hair Changes Caused by Aging
Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
research Hair Growth Promotion, Cytotoxicity, and Skin Permeability Evaluations of Carthamus Tinctorius Floret Extract
Carthamus tinctorius floret extract is a safe hair growth promoter with good skin absorption.
research Receptors in Trichology: Hot Spots for Hair Regeneration
Vitamin D3 and its receptor are important for hair growth, and understanding receptors could help treat hair graying and skin cancer.
research Combined Melanocytic Nevus Presenting with Scalp Alopecia Associated with Alopecia Areata: Coincidence or Causal?
A man's scalp hair loss was due to a combined melanocytic nevus and alopecia areata, suggesting a possible link between the two conditions.
research Fabrication and Characterization of Epithelial Scaffolds for Hair Follicle Regeneration
The study found that certain three-dimensional scaffolds can help regenerate hair effectively.
research Systemic Corticosteroids in Vitiligo
Systemic corticosteroids can help treat rapidly spreading vitiligo but require more research for safer use.
research A Woman With Headaches And Blurred Vision
The woman was diagnosed with Vogt–Koyanagi–Harada disease and successfully treated with medication, restoring her vision and stopping headaches.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Viewpoint 1
Understanding skin patterns can help us learn about skin diseases and their treatments.
research The Hair Pigmentation Unit And Hair Graying
Hair color is due to active pigment cells in hair during growth.
research Leukotrichia Developed Following Application of Intense Pulsed Light for Hair Removal
Some people's hair turned white or gray after using intense pulsed light for hair removal, and for some, it was permanent.
research N02. Hair and Nails
Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.
research Ultraviolet And Androgenetic Alopecia
Protecting hair and scalp from sunlight may help prevent hair loss.