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This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.

In this review, the authors summarize the phytochemistry, pharmacology, and medicinal uses of Hibiscus rosa sinensis, highlighting its various benefits such as hypotensive and anti-inflammatory effects, while noting the need for more research on its specific mechanisms and potential toxicities.

In this study, herbal extracts commonly used in traditional medicine were observed to significantly increase the proliferation of human dermal papilla cells, suggesting potential as alternative therapies for enhancing hair growth.

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

This study suggests that Ecklonia cava, particularly its component dioxinodehydroeckol, may promote hair growth by enhancing dermal papilla and outer root sheath cell activity in culture and mice models.

In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.

This study found that finasteride decreased DHT-stimulated AR activity and cell growth in prostate cancer cells with mutant AR, but not in those with wild type AR.

This study found that hair regrowth in Pomeranians with hair cycle arrest treated with melatonin was not associated with a change in oestrogen receptor-α staining.

This study reports that the novel small molecule IM176OUT05, by modifying stem cell metabolism, promoted hair regrowth and increased hair follicle numbers in mice.

This study developed a triple drug delivery system using nanoparticles loaded with 5-fluorouracil, curcumin, and piperine to target breast tumors, demonstrating notable in vitro cytotoxicity and anti-metastatic potential in 3D tumor spheroids which suggests its promise for further preclinical evaluation.

This review discusses the potential link between long-term transdermal exposure to sex hormones from antiperspirants and increased breast and prostate cancer rates, calling for further research to confirm this theory.

In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.

This review summarizes the promising role of melatonin combined with nanosized carriers in drug delivery, suggesting enhanced effectiveness in treating various diseases compared to free melatonin.

This study found that PEGylation of nanoparticles enhances their penetration into hair follicles, with higher molecular weight PEG resulting in deeper follicular delivery.

This review discusses the development and application of cell-derived matrices in regenerative medicine and disease modeling, presenting various fabrication techniques and future perspectives, but reports no new results.

This study investigated a nanostructured system using PS-b-PAA diblock copolymer for incorporating the hydrophobic photosensitizer ClAlPc, finding it effective in causing cellular damage in Caco-2 cells under light while demonstrating no cytotoxicity without light, suggesting its potential use in photodynamic therapy.

This review presents current evidence on medicinal plants and their phytoconstituents, such as phenolic compounds, used in acne treatment, highlighting their potential as alternatives to conventional therapies due to issues like antibiotic resistance and high cost.

This study found that Polygonum multiflorum extract may promote hair growth by increasing anagen duration and activating dermal papilla cells in human hair follicles, as observed in cultured cell models.

This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.

This review discusses various Wnt pathway modulators developed between 2014 and 2020, highlighting their potential as treatments for diseases like cancer and osteoarthritis, but reports no new clinical results.

This study reviews recent advancements in understanding caspases, highlighting their roles beyond apoptosis in cancer, inflammation, and neurological disorders, and discusses the potential and challenges of targeting caspases for therapeutic purposes.

In this study, high levels of the protein Flii in mice were associated with worsened symptoms and inflammation in ulcerative colitis, suggesting Flii may inhibit mucosal healing.

This study found that metabolism-related genes significantly impact the prognosis and metastasis in breast cancer, and the development of prediction models may guide personalized therapeutic strategies.

This study found that the PP2A-B55α regulatory subunit is crucial for ectodermal development in mice, with knockout embryos displaying severe neural and epidermal defects and failing to survive to birth.

This review summarizes the enhanced absorption and bioavailability of phytosome delivery systems, which combine herbal extracts with phospholipids to improve therapeutic potential, and provides an updated overview of their development, commercial availability, and patented technologies.

This article reviews the potential for low intensity ultrasound as an antidote for the peripheral cytotoxic side effects of taxane drugs in chemotherapy, presenting no new clinical results.

This study established a rapid and accurate ultra-performance liquid chromatographic method for chemical fingerprinting and analyzing Platycladi cacumen, effectively distinguishing batches based on geographical and climatic conditions.

This study found that antroquinonol inhibited CD8+ T cell proliferation and reduced proinflammatory cytokine secretion in vitro, while also ameliorating H2O2-induced depigmentation and resisting reductions in hair follicle length, skin thickness, and tyrosinase expression in mice.

This study found that β-catenin is essential for hair follicle stem cell proliferation and may regulate this process through the PI3K/Akt pathway, suggesting its potential as a therapeutic target.