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This study found that overexpression of AKR1C3 in prostate cancer cells redirected androgen metabolism towards testosterone production, which facilitated cell proliferation, potentially reducing the effectiveness of finasteride treatment.

This study found that sebaceous glands predominantly exhibit oxidative activity of the type 2 17β-hydroxysteroid dehydrogenase isozyme, which is not inhibited by 13-cis retinoic acid.

In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.

This review discusses the mechanisms and engineering techniques for enhancing the targeted delivery of extracellular vesicles in therapies but reports no new clinical findings; the authors encourage further exploration to advance clinical applications.

This study found that combining minoxidil with all-trans retinoic acid additively promoted hair growth in vitro by activating certain cell survival pathways and reducing apoptosis markers more effectively than minoxidil alone.

In this study, synthetic vitamin D3 analogs stimulated hair growth and formation of normal hair follicles in nude mice, unlike the natural form 1,25 dihydroxyvitamin D3.

This review discusses recent research and applications of RADA16 and RADA16-based peptide scaffolds in biomedicine, including their roles in tissue repair and drug delivery, but reports no new clinical results.

This study demonstrated that tight junction barriers exist in human hair follicles but are less tight in hair follicle keratinocytes than in interfollicular keratinocytes, highlighting claudin-1's key role in follicle barrier function and growth.

This study found that combining herbal extracts with PRP increased human dermal papilla cell proliferation via ERK and Akt protein regulation, suggesting its potential for developing hair growth therapies.

This review discusses the potential role of extracellular vesicles in modulating hair follicle dynamics and reports no new clinical results; future investigations may inform treatment strategies for skin disorders.

This review explores potential indications for prolactin receptor inhibitors beyond breast and prostate cancers, emphasizing the need for potent antibodies to further research prolactin receptor expression.

This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.

In this in vitro study, minoxidil, diazoxide, and the novel compound NNC 55-0118 increased hair follicle growth, supporting deer follicles as a viable bioassay for ATP-sensitive potassium channel modulators.

This study found that Ecklonia cava enzymatic extract, particularly its component dieckol, promoted hair growth by increasing dermal papilla cell proliferation and inhibiting 5α-reductase activity in cultured vibrissa follicles and C57BL/6 mice.

This review compiles studies on the antidiabetic potential of plants from the Middle East, particularly from the Asteraceae and Lamiaceae families, but reports no clinical results.

This study demonstrated that topical oleuropein induced hair growth in mice by activating the Wnt10b/β-catenin signaling pathway and increasing expression of several growth-related genes in skin tissue.

This review reports on the traditional and ethnopharmacological uses of Ziziphus jujuba Mills, noting its increasing global popularity for treating various ailments, but highlights that its acceptance into the European Pharmacopoeia remains unresolved due to scientific and regulatory challenges.

This review discusses the traditional uses and pharmacological properties of Hedychium spicatum, noting that while some traditional uses are supported by scientific studies, further research on its applications is needed.

This case report describes fetal malformations and placental abnormalities in a pregnant woman who applied minoxidil topically, suggesting potential risks of its use during pregnancy.

This study found that ginsenoside Rb1 promoted the growth of mink hair follicles and dermal papilla cells, potentially through activating the PI3K/AKT/GSK-3β signaling pathway.

This review classifies engineered nanomaterials by composition and application in biomedicine, highlighting diverse uses like regenerative medicine and potential occupational side effects, but reports no new clinical results.

This study found that Sp6 overproduction in ameloblast-lineage cells increased cell proliferation and ameloblastin expression, suggesting that Sp6 promotes amelogenesis by inhibiting follistatin gene expression.

This study found that melatonin's effect on HaCaT keratinocyte proliferation varied with concentration and incubation time, with no cytotoxic effects observed at suitable concentrations for skin treatment.

This review discusses the potential of 4-azasteroids as 5α-reductase inhibitors for treating hirsutism, reporting their promising effects in animal studies but noting no clinical trials have been conducted yet.

This article reviews the role of microRNAs as epigenetic modulators in dermatology but reports no new clinical findings.

This study found that some synthesized heterocyclic derivatives showed promising 5α-reductase inhibitor, antiviral, and anti-tumor activities, surpassing several reference drugs in effectiveness.

This article reviews the potential neuroprotective effects of 17α‐estradiol in neurodegenerative diseases and highlights its possibly lower toxicity compared to more feminizing hormones, but it reports no new clinical findings.

This study found that hair products commonly used by Black women exhibited hormonal activity, which could impact health outcomes and contribute to health disparities.

This review examines patents and publications on steroid sulfatase inhibitors since 1999 and reports no new clinical results, highlighting their potential for treating estrogen- and androgen-driven conditions.

This review discusses the pharmacological actions of mangiferin and the potential of delivery carriers to overcome its limitations, but reports no new clinical results.