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    Glossary Matrix Metalloproteinase-9

    enzyme that breaks down extracellular matrix proteins

    Matrix Metalloproteinase-9 (MMP-9), also known as gelatinase B, is an enzyme that breaks down the extracellular matrix, which is the network of proteins and molecules surrounding cells. This process is crucial for tissue remodeling, wound healing, and the progression of certain diseases, including cancer and inflammatory conditions. Elevated levels of MMP-9 are often associated with pathological conditions such as chronic inflammation and tumor metastasis.

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    1. Matrix Metalloproteinase-9 Is Involved in the Regulation of Hair Canal Formation 2010 · 20 citations
    2. Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle Experimental and Therapeutic Medicine · 2016 · 21 citations
    3. Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation Journal of Investigative Dermatology · 2003 · 56 citations
    4. Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts Archives of Dermatological Research · 2005 · 9 citations
    5. A polymorphism in the matrix metalloproteinase-1 gene promoter is associated with the presence of polycystic ovary syndrome in Caucasian women Fertility and Sterility · 2005 · 8 citations
    6. Procyanidins attenuate neuropathic pain by suppressing matrix metalloproteinase-9/2 Journal of Neuroinflammation · 2018 · 22 citations
    7. In-Vitro Anticancer Activity of Chemical Constituents from Etlingera alba Poulsen against Triple Negative Breast Cancer and in silico Approaches towards Matrix metalloproteinase-1 Inhibition Indonesian Journal of Science and Technology · 2022 · 7 citations
    8. A bio-polymeric scaffold incorporated with p-Coumaric acid enhances diabetic wound healing by modulating MMP-9 and TGF-β3 expression Colloids and surfaces. B, Biointerfaces · 2023 · 1 citations
    9. Oral Centella asiatica Extract Attenuates UVB-Induced Skin Photoaging via Antioxidant, Anti-Inflammatory, and Extracellular Matrix-Preserving Effects in Hairless Mice International Journal of Molecular Sciences · 2025
    10. Human Fibroblast‐Derived Matrix Hydrogel Accelerates Regenerative Wound Remodeling Through the Interactions with Macrophages Advanced science · 2024
    11. 879 IL-9 mediated human primary keratinocytes invasion is dependent on MLC controlled contractility and independent of MMP activity Journal of Investigative Dermatology · 2018
    12. Effect of Decellularized Extracellular Matrix Bioscaffolds Derived from Fibroblasts on Skin Wound Healing and Remodeling Frontiers in bioengineering and biotechnology · 2022 · 8 citations
    13. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    14. Identification of clustered cells in human hair follicle responsible for MMP‐9 gelatinolytic activity: consequences for the regulation of hair growth International Journal of Dermatology · 2001 · 27 citations
    15. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression Drug Design Development and Therapy · 2015 · 27 citations
    16. Network pharmacology and molecular docking analysis on potential molecular targets and mechanism of action of BRAF inhibitors for application in wound healing Journal of Cellular Biochemistry · 2023 · 11 citations
    17. Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland Frontiers in Pharmacology · 2023 · 2 citations
    18. Engineering MMP9-Responsive Antioxidative Micelle-Hydrogel Dressings for Sequential Inflammatory Remodeling and Pro-Angiogenesis in Diabetic Wound Healing Precision medicine and engineering. · 2026
    19. The Role of Moracin M in Promoting Hair Growth: Insights into Mechanisms of WNT/β- Catenin Pathway Activation and Angiogenesis Enhancement in Human Dermal Papilla Cells Research Square (Research Square) · 2024
    20. Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia Medicine · 2023
    21. 13. Wound Healing & Hair Journal of Cutaneous Medicine and Surgery · 2003
    22. Wound Healing: A Cellular Perspective Physiological Reviews · 2018 · 1160 citations
    23. Scarless wound healing: Transitioning from fetal research to regenerative healing Wiley Interdisciplinary Reviews-Developmental Biology · 2018 · 79 citations
    24. 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α American Journal Of Pathology · 2010 · 38 citations
    25. Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia Journal of The American Academy of Dermatology · 2018 · 25 citations
    26. Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models Lasers in Medical Science · 2016 · 24 citations
    27. Identifying key components and therapeutic targets of the immune system in hidradenitis suppurativa with an emphasis on neutrophils 2020 · 16 citations
    28. Ameliorative effect of tranexamic acid on physiological skin aging and its sex difference in mice Archives of dermatological research · 2019 · 13 citations
    29. Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway International Journal of Biological Sciences · 2023 · 9 citations
    30. In Vivo Evaluation of<i>Eclipta alba</i>Extract as Anticancer and Multidrug Resistance Reversal Agent Nutrition and Cancer · 2014 · 9 citations