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    Glossary Matrix Metalloproteinases

    enzymes that degrade extracellular matrix proteins

    Matrix Metalloproteinases (MMPs) are a group of enzymes that break down proteins in the extracellular matrix, which is the network of molecules surrounding cells. They play a crucial role in tissue remodeling, wound healing, and various physiological processes, but their overactivity can contribute to diseases like arthritis and cancer.

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    1. A polymorphism in the matrix metalloproteinase-1 gene promoter is associated with the presence of polycystic ovary syndrome in Caucasian women Fertility and Sterility · 2005 · 8 citations
    2. Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia Medicine · 2023
    3. Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia Journal of The American Academy of Dermatology · 2018 · 25 citations
    4. Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models Lasers in Medical Science · 2016 · 24 citations
    5. Expression Profiling and Cellular Localization of Genes Associated with the Hair Cycle Induced by Wax Depilation 2005 · 27 citations
    6. Modulation of Photoaging-Induced Cutaneous Elastin: Evaluation of Gene and Protein Expression of Markers Related to Elastogenesis Under Different Photoexposure Conditions Dermatology and Therapy · 2021 · 14 citations
    7. Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus Infection Cell Host & Microbe · 2016 · 133 citations
    8. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    9. In Vivo Evaluation of<i>Eclipta alba</i>Extract as Anticancer and Multidrug Resistance Reversal Agent Nutrition and Cancer · 2014 · 9 citations
    10. Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture Nature cell biology · 2024 · 2 citations
    11. Mammalian Fetal Organ Regeneration 2005 · 32 citations
    12. 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages Journal of Investigative Dermatology · 2017
    13. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    14. An in silico approach to the identification of potential proteomic and genomic diagnostic biomarkers for primary cicatricial alopecia Experimental Dermatology · 2021
    15. <i>Col4a2-eGFP</i>mouse model reveals the molecular and functional dynamics of basement membrane remodelling in hair follicle morphogenesis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    16. Matrisomal components involved in regenerative wound healing in axolotl and <i>Acomys</i>: implications for biomaterial development Biomaterials Science · 2023
    17. Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice Nutrients · 2022 · 4 citations
    18. The effects of infrared radiation on the human skin Photodermatology, Photoimmunology and Photomedicine · 2023
    19. Desmodesmus pannonicus Water Extract Inhibits Melanin Synthesis and Promotes Wound Healing Life · 2024 · 1 citations
    20. Biological activities supporting development of cosmeceutical skin products from Wedelia trilobata (L.) Hitch. flower extract Agriculture and Natural Resources · 2023 · 3 citations
    21. Malignant Melanoma and Its Stromal Nonimmune Microecosystem Journal of Oncology · 2012 · 10 citations
    22. Clinical Snippets Experimental Dermatology · 2015
    23. Curcumin and cancer biology: Focusing regulatory effects in different signalling pathways Phytotherapy Research · 2021 · 27 citations
    24. New treatments for rheumatoid arthritis Postgraduate Medicine · 1999 · 13 citations
    25. Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing Molecular Pharmaceutics · 2013 · 40 citations
    26. Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts Archives of Dermatological Research · 2005 · 9 citations
    27. The systemic wrinkled skin phenotype involves aberrant expression and variation of genes related to the oxidative stress and extracellular matrix in Xiang pigs BMC Genomics · 2025
    28. Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation Journal of Investigative Dermatology · 2003 · 56 citations
    29. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    30. Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle Experimental and Therapeutic Medicine · 2016 · 21 citations