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    Glossary Matrix Metalloproteinases

    enzymes that degrade extracellular matrix proteins

    Matrix Metalloproteinases (MMPs) are a group of enzymes that break down proteins in the extracellular matrix, which is the network of molecules surrounding cells. They play a crucial role in tissue remodeling, wound healing, and various physiological processes, but their overactivity can contribute to diseases like arthritis and cancer.

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    1. Matrix Metalloproteinase-19 Expression in Normal and Diseased Skin: Dysregulation by Epidermal Proliferation Journal of Investigative Dermatology · 2003 · 56 citations
    2. Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle Experimental and Therapeutic Medicine · 2016 · 21 citations
    3. Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts Archives of Dermatological Research · 2005 · 9 citations
    4. Collagenase IV plays an important role in regulating hair cycle by inducing VEGF, IGF-1, and TGF-β expression Drug Design Development and Therapy · 2015 · 27 citations
    5. Expression Profiling and Cellular Localization of Genes Associated with the Hair Cycle Induced by Wax Depilation 2005 · 27 citations
    6. 1396 Interferon-24 regulates the expression of MMP1 and dermal collagen of the skin Journal of Investigative Dermatology · 2023
    7. Modulation of Photoaging-Induced Cutaneous Elastin: Evaluation of Gene and Protein Expression of Markers Related to Elastogenesis Under Different Photoexposure Conditions Dermatology and Therapy · 2021 · 14 citations
    8. A bio-polymeric scaffold incorporated with p-Coumaric acid enhances diabetic wound healing by modulating MMP-9 and TGF-β3 expression Colloids and surfaces. B, Biointerfaces · 2023 · 1 citations
    9. Update in minimally invasive periorbital rejuvenation with a focus on platelet‐rich plasma: A narrative review Journal of cosmetic dermatology · 2020 · 15 citations
    10. Mammalian Fetal Organ Regeneration 2005 · 32 citations
    11. Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models Lasers in Medical Science · 2016 · 24 citations
    12. Identification of immune microenvironment changes, immune-related pathways and genes in male androgenetic alopecia Medicine · 2023
    13. 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages Journal of Investigative Dermatology · 2017
    14. Defining stem cell dynamics and migration during wound healing in mouse skin epidermis Nature Communications · 2017 · 363 citations
    15. Effects of autologous platelet‑rich plasma injections on facial skin rejuvenation Experimental and Therapeutic Medicine · 2020 · 40 citations
    16. Saponins of Korean Red Ginseng May Protect Human Skin from Adipokine-Associated Inflammation and Pigmentation Resulting from Particulate Matter Exposure Nutrients · 2022 · 4 citations
    17. 686 Topical melatonin unfolds differential anti-aging effects in human skin by inhibiting mTORC1 activity via TSC2 stimulation Journal of Investigative Dermatology · 2024
    18. Fibroproliferative genes are preferentially expressed in central centrifugal cicatricial alopecia Journal of The American Academy of Dermatology · 2018 · 25 citations
    19. Comparison of two ASC-derived therapeutics in an in vitro OA model: secretome versus extracellular vesicles Stem Cell Research & Therapy · 2020 · 60 citations
    20. Connective tissue sheath of hair follicle is a major source of dermal type I procollagen in human scalp Journal of dermatological science · 2012 · 4 citations
    21. Matrisomal components involved in regenerative wound healing in axolotl and <i>Acomys</i>: implications for biomaterial development Biomaterials Science · 2023
    22. Self-organization process in newborn skin organoid formation inspires strategy to restore hair regeneration of adult cells Proceedings of the National Academy of Sciences of the United States of America · 2017 · 92 citations
    23. 13. Wound Healing & Hair Journal of Cutaneous Medicine and Surgery · 2003
    24. Antiaging Activity of Peptide Identified from Fermented <i>Trapa Japonica</i> Fruit Extract in Human Dermal Fibroblasts Evidence-based Complementary and Alternative Medicine · 2020 · 14 citations
    25. Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts International Journal of Molecular Sciences · 2018 · 68 citations
    26. In Vivo Evaluation of<i>Eclipta alba</i>Extract as Anticancer and Multidrug Resistance Reversal Agent Nutrition and Cancer · 2014 · 9 citations
    27. Thymosin β<sub>4</sub>increases hair growth by activation of hair follicle stem cells The FASEB Journal · 2003 · 98 citations
    28. Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging Journal of Investigative Dermatology · 2020 · 14 citations
    29. Commentary on Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth Dermatologic Surgery · 2012 · 13 citations
    30. Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model European journal of pharmacology · 2015 · 10 citations