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    Glossary matrix keratinocytes

    specialized cells producing keratin proteins for hair growth

    Matrix keratinocytes are specialized cells located in the hair bulb at the base of the hair follicle. These cells are responsible for producing the keratin proteins that make up the hair shaft, playing a crucial role in hair growth and regeneration.

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    1. Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte cytotoxicity Frontiers in Pharmacology · 2025 · 4 citations
    2. 085 Dermal papilla cells control hair follicle matrix keratinocytes proliferation through versican Journal of Investigative Dermatology · 2024
    3. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    4. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations
    5. Exogenous stimulation with Eclipta alba promotes hair matrix keratinocyte proliferation and downregulates TGF-β1 expression in nude mice International Journal of Molecular Medicine · 2014 · 24 citations
    6. Melatonin protects K15+ human hair follicle stem cells and hair matrix keratinocytes against paclitaxel-induced damage ex vivo Journal of Investigative Dermatology · 2023 · 1 citations
    7. 764 DNA dioxygenases Tet1/2/3 control hair matrix keratinocyte differentiation and hair shaft shape via regulation of hair keratin gene expression 2020
    8. 877 Integration of magnetic tweezers and traction force microscopy for exploring the mechanobiology of keratinocyte cell-cell and cell-matrix anchoring junctions Journal of Investigative Dermatology · 2018
    9. 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts Journal of Investigative Dermatology · 2020
    10. Culture of hair matrix and follicular keratinocytes Journal of Investigative Dermatology · 1993 · 26 citations
    11. Differential effects of caffeine on hair shaft elongation, matrix and outer root sheath keratinocyte proliferation, and transforming growth factor‐β2/insulin‐like growth factor‐1‐mediated regulation of the hair cycle in male and female human hair follicles<i>in vitro</i> British Journal of Dermatology · 2014 · 60 citations
    12. Hair-Growth-Promoting Effect of Conditioned Medium of High Integrin α6 and Low CD 71 (α6bri/CD71dim) Positive Keratinocyte Cells International Journal of Molecular Sciences · 2015 · 17 citations
    13. Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication Matrix Biology · 2016 · 57 citations
    14. Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing Diabetes · 2021 · 25 citations
    15. YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate International Journal of Molecular Sciences · 2024 · 14 citations
    16. Radiofrequency Currents Modulate Inflammatory Processes in Keratinocytes International Journal of Molecular Sciences · 2024 · 3 citations
    17. FAM19A5 negatively regulates cutaneous wound healing via PPARD-dependent inhibition of keratinocyte migration Scientific Reports · 2026
    18. 090 Reactive lipids from the secretome of senescent fibroblasts modify the extracellular matrix with functional consequences for resident cells Journal of Investigative Dermatology · 2024
    19. 879 IL-9 mediated human primary keratinocytes invasion is dependent on MLC controlled contractility and independent of MMP activity Journal of Investigative Dermatology · 2018
    20. In Vitro Differences Between Keratinocyte Stem Cells and Transit-Amplifying Cells of the Human Hair Follicle Journal of Investigative Dermatology · 2005 · 52 citations
    21. Stimulatory Effect of Brazilian Propolis on Hair Growth through Proliferation of Keratinocytes in Mice Journal of Agricultural and Food Chemistry · 2014 · 18 citations
    22. 604 DNA dioxygenases TET regulate keratin gene expression and enhancer networks within lineage-specific gene loci during epidermal and hair follicle-specific keratinocyte differentiation 2021
    23. Effect of Minoxidil on Cultured Keratinocytes Journal of Investigative Dermatology · 1983 · 72 citations
    24. Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid Stem cells international · 2017 · 42 citations
    25. Modulation of the differentiated phenotype of keratinocytes of the hair follicle and from epidermis Journal of Dermatological Science · 1994 · 41 citations
    26. Cultured nail keratinocytes express hard keratins characteristic of nail and hair in vivo Archives of dermatological research · 1992 · 16 citations
    27. Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers Journal of Biomaterials Science Polymer Edition · 2020 · 11 citations
    28. Single‐Cell Analysis of Late‐Stage Wound‐Induced Hair Follicle Neogenesis Reveals Keratinocyte Heterogeneity and Enrichment of Infundibular Basal Keratinocytes Experimental Dermatology · 2026
    29. 866 Senescent fibroblasts secretome promote tumoural initiation of normal human keratinocytes through cellular activation, enhanced migration and ECM remodelling European Journal of Cancer Supplements · 2010
    30. Dermal papilla cells induce keratinocyte tubulogenesis in culture Elina S. ChermnykhEkaterina A. VorotelyakKsenia Y. Gnedeva • Marianna V. MoldaverYegor E. YegorovAndrey V. Vasiliev • 2010