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This study introduces a spherical skin model that effectively mimics key features of human skin, offering a scalable and rapid alternative for non-animal dermatological and cosmetic testing.

This study observed that using an environmentally friendly bovine milk permeate effectively and cleanly removes wool from sheepskins without harming the skin, and results in smoother leather compared to traditional chemical methods.

In this review, the authors examined the role of the extracellular matrix in cancer progression and highlighted how decellularization techniques are used to create biomimetic tumor models, discussing the potential for personalized and predictive cancer treatments using advanced biomaterials combined with AI and machine learning.

This study reported an unusual case of nail matrix involvement and trachyonychia in a child with juvenile pityriasis rubra pilaris, showing significant improvement with topical therapy and oral biotin.

In this study, researchers found that hair follicle-derived mesenchymal stem cells, modified to overexpress extracellular matrix protein 1, significantly improved liver function and reduced liver damage in cirrhotic mice by inhibiting hepatic stellate cell activation and TGF-β/Smad signaling.

This review discusses the fundamental hallmarks of aging as they relate to skin aging and highlights the prominent roles of oxidative damage and the extracellular matrix in photoaging, reporting no new results.

This study found that serum-free expanded hair follicle mesenchymal stem cells (hfMSCs), derived from hair plucking, significantly improved cartilage repair in a murine model despite minimal engraftment, suggesting their effectiveness through a paracrine mechanism.

This study developed a novel hydrogel combining Chlorella extracellular polysaccharide–selenium nanoparticles (EPS-SeNPs) with biocompatible components, which demonstrated strong antibacterial and anti-inflammatory effects, significantly accelerating wound healing in an infected rat model, and enabling pH-based monitoring of healing.

This review discusses cellular senescence in human skin, detailing both beneficial and detrimental effects and suggesting the potential for therapies targeting senescence-related skin disorders, but reports no new clinical results.

In an animal study, this research explored the use of a self-therapeutic nanoparticle for treating psoriasis in mice, finding that it could prevent and treat psoriatic symptoms as effectively as standard therapies without causing side effects like hair loss and skin wrinkling.

This study provides a comprehensive framework for understanding, managing, and addressing skin fibrosis, highlighting common pathways and new therapeutic opportunities for various fibrosis-related disorders that currently lack effective treatments.

This study reports that a pH-responsive nanosilver platform improved wound healing in mouse and rabbit models by targeting bacteria and supporting tissue repair more effectively than traditional silver nanoparticles.

This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.

This study found that dihydrotestosterone induces hair loss in male C57BL/6 mice, and this effect can be partially reversed by the androgen receptor antagonist bicalutamide.

In this article, the authors detail their experience with AltrenoTM, a new topical retinoid lotion used for treating mild to moderate acne, reporting clinical effectiveness and satisfactory tolerability among patients of various ages, including children as young as 9.

This study suggests that Lychnophora salicifolia Mart. extract in liposomal formulations could serve as an effective topical photochemopreventive agent by improving skin penetration and reducing oxidative and inflammatory damage from ultraviolet radiation.

This study used a novel extraction method to detect and measure mineralocorticoids and glucocorticoids in hair follicles, concluding these steroids may serve as effective biomarkers for diagnosing conditions related to steroid excess or deficiency, such as Cushing’s syndrome and congenital adrenal hyperplasia.

This research highlights the potential of using bioactive silk-based nanofiber dressings to improve the healing of diabetic wounds, suggesting that further studies are needed to refine these formulations and confirm their effectiveness in larger clinical trials.

This review highlights recent advancements in using nanotechnology for scar prevention and treatment, emphasizing the unique properties of nanomaterials in drug delivery and the challenges that remain in maximizing their potential for effective scar interventions.

This study reported that atelocollagen enhances collagen synthesis and reduces oxidative stress in aged skin by increasing glycine uptake through GlyT1, resulting in improved skin elasticity and collagen density in aged mice, with effects superior to glycine alone.

This study describes the development of a minoxidil gel using the copolymer Sepineo P 600, showing improved spreadability, occlusivity, adhesiveness, and stability compared to minoxidil lotion, without causing skin corrosion, making it a potentially more effective treatment form for alopecia areata.

This review reports that biopolymer-based hydrogels show promise as wound dressings due to their biocompatibility, moisture retention, and ability to mimic the extracellular matrix, though challenges in mass production, safety, and clinical validation remain.

In this study, araliadiol, a plant-derived compound, exhibited senomorphic effects in three dermal fibroblast senescence models, suggesting its potential as a topical treatment to mitigate skin aging by reducing certain senescence-related markers and increasing procollagen type I content.

This study found that incorporating Canavalia ensiformis lectin into alginate and carboxymethylcellulose films enhanced angiogenic factor expression, suggesting these biopolymer films could be an effective alternative for wound treatment.

This review summarizes the potential of single traditional Chinese medicines and extracts in preventing and treating renal fibrosis, emphasizing their capacity to inhibit transforming growth factor β and reduce extracellular matrix formation, but it reports no new clinical results.

This study found that photodynamic therapy achieved permanent removal of nonpigmented hair in mice after multiple sessions, unlike laser treatment, which was not effective for nonpigmented hair.

The treatments for fungal nail infection, hair loss in men, benign nail tumor, and chemotherapy-associated nail bed inflammation are effective and safe.

In this study, researchers developed a novel method using ultrasound stimulation and a hydrogel delivery system to enhance the regenerative effects of stem cell-derived extracellular vesicles on severe skin injuries, resulting in improved healing and hair follicle regeneration in a mouse model.

In this study, researchers developed a long-lasting antibacterial coating for medical implants by anchoring silver nanoparticles onto polyamide surfaces, demonstrating potential to improve implant safety and effectiveness by reducing infection and inflammation.

This study presents a novel assay that allows for the simultaneous measurement of various androgens and 5α-reductase inhibitors in male serum, facilitating research into the biochemical effects of these inhibitors.