5 citations
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October 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the authors found that inhibiting Cdc42 activity with CASIN restored hair follicle stem cell function and hair growth in aged mice, suggesting potential for treating aging-related hair regeneration issues.
April 2026 in “International Journal of Research and Review” This article reviews current literature and suggests that managing gout with early urate-lowering therapy, within a 'treat-to-target' strategy, can help prevent systemic complications and address the rising prevalence of hyperuricemia-related diseases.
October 2020 in “Research Square (Research Square)” This study found that treating aged mice with the Cdc42 inhibitor CASIN restored hair follicle stem cell functionality and improved hair regeneration by inducing anagen onset and increasing anagen skin areas.
25 citations
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November 2020 in “Proceedings of the National Academy of Sciences” This study found that the HoxC gene cluster plays a critical role in the development of ectodermal organs, including hair and nails, with mammalian-specific enhancers increasing transcription levels during development.
20 citations
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December 2013 in “PLoS ONE” This study found that β1 integrin-mediated signaling is crucial for the survival, adhesion, and migration of epithelial progenitor cells in human scalp hair follicles, with varying responses observed among cell subpopulations.
17 citations
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December 2011 in “Journal of the European Academy of Dermatology and Venereology” People with vitiligo may have a lower risk of heart disease.
June 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the HoxC gene cluster is crucial for the development of hair and nails in mice, with key regulation by two mammalian-specific enhancers.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, the researchers found that deleting ceramide synthase 4 in the skin's epidermis alters stem cell differentiation, disrupting hair follicle structure and barrier function, potentially leading to immune responses similar to atopic dermatitis.
January 2022 in “Figshare” This study found that inhibiting autophagy in mouse preputial glands alters lipid metabolism, delays aging-related duct changes, and reduces pheromone production, indicating autophagy's critical role in gland homeostasis and cell breakdown during secretion.
January 2021 in “Figshare” This study found that autophagy in the preputial glands of mice plays a crucial role in regulating lipid and fatty acid metabolism, as well as pheromone production.
November 2024 in “PubMed” Results of the effect and safety of a gummy supplement with B vitamins, zinc, and botanicals on hair growth and quality in women with thinning hair are not reported in this abstract.
This research suggests that the digit ratio, 2D:4D, is unlikely to be a significant indicator of male androgenetic alopecia, contradicting a prominent isolated finding from a previous study.
6 citations
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December 2023 in “Lancet. Infectious diseases/The Lancet. Infectious diseases” This study found that treatment with the synbiotic SIM01 significantly alleviated multiple symptoms of post-acute COVID-19 syndrome compared to placebo, suggesting potential management benefits through gut microbiome modulation.
6 citations
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September 2021 in “Autophagy” In this study on mouse preputial glands, suppressing ATG7-dependent autophagy delayed age-related changes, affected lipid metabolism, and reduced pheromone production, highlighting autophagy's roles in glandular homeostasis and cell breakdown.
In this study, a polyphenol and biotin supplement improved skin roughness and significantly reduced hair shedding, but did not demonstrate clear superiority over placebo in overall skin outcomes.
14 citations
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June 2014 in “World Journal of Urology” This study found that the herbal combination PRO 160/120 significantly improved nocturnal voiding frequency in patients with moderate-to-severe LUTS/BPH compared to placebo, with similar effectiveness to tamsulosin and finasteride.
July 2025 in “Frontiers in Medicine” In this systematic review and meta-analysis, the authors examined single-spin versus double-spin centrifugation protocols for PRP in patients with androgenic alopecia and found no significant difference in platelet concentration, hair density, or hair types between the protocols.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study found no significant differences in platelet concentration or hair growth outcomes between single-spin and double-spin PRP centrifugation methods for treating androgenic alopecia, suggesting that the simpler single-spin approach may be preferable.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this systematic review and meta-analysis, the researchers found no significant difference in platelet concentration, hair density improvement, or changes in terminal and vellus hair rates between single-spin and double-spin PRP centrifugation protocols in treating androgenic alopecia.
March 2010 in “The Journal of Urology” This study found that men with early-onset androgenetic alopecia had larger prostate volumes and lower urinary flow rates compared to those without the condition, suggesting a potential link between AGA and urinary symptoms.
66 citations
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October 1987 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that serum 3 alpha-diol G levels in women with idiopathic hirsutism correlated well with their clinical response to treatment, suggesting its usefulness in evaluating treatment outcomes.
12 citations
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May 2017 in “Journal of Dermatological Treatment” This study found that in adults over 25, stress from lifestyle changes, sensitive skin, stopping oral contraceptives, and the use of full-coverage foundations were associated with increased severity of acne.
9 citations
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January 2015 in “Springer eBooks” This article reviews the diagnostic criteria and management strategies for polycystic ovary syndrome but reports no new clinical findings; it highlights associated health risks and recommended treatments.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This source reviews the influence of sex hormones on skin health, detailing how hormonal fluctuations impact dermatological conditions throughout a woman's life and highlighting the necessity for integrated dermatological, gynecological, and endocrine care alongside mental health support to address these conditions' physical and psychological effects.
October 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This review describes how sex hormones like estrogens and androgens influence skin health, linking hormonal fluctuations to conditions such as acne and hair loss, and underscores the importance of a multidisciplinary approach to treatment that includes mental health support.
February 2024 in “Journal of Education, Health and Sport” This review discusses current pharmacological and non-pharmacological treatment strategies for PCOS, emphasizing the need for a personalized, multimodal approach due to incomplete understanding of the syndrome's pathogenesis.
August 2025 in “Journal of Pediatric Endocrinology and Metabolism” This case report from a German study detailed a 2-year-old girl with virilization and precocious puberty due to a rare ovarian steroid cell tumor, finding that post-surgery, her elevated hormone levels normalized within a week, and ongoing follow-up showed no need for chemotherapy.
October 2025 in “World Journal of Biology Pharmacy and Health Sciences” This review highlights the role of sex hormones in skin health, observing that hormonal changes throughout a woman's life can affect skin conditions such as acne and hair loss, with treatments involving hormonal therapies and the importance of a multidisciplinary approach.
8 citations
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January 1986 in “The Journal of Dermatologic Surgery and Oncology” This article discusses surgical treatments for male pattern hair loss in black individuals, emphasizing the need for technique adjustments due to specific characteristics of black skin and hair, but reports no new clinical results.
502 citations
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February 2008 in “The Journal of Clinical Endocrinology & Metabolism” This review discusses hirsutism management guidelines, recommending androgen testing only for women with abnormal hirsutism scores and advocating for combined therapy approaches depending on severity and underlying conditions, but it reports no new clinical results.