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This study suggests that an extract from Malva verticillata seeds could help treat hair loss by modulating the Wnt/β-catenin pathway in cultured human dermal papilla cells.

Tanshinone Capsule may help regrow hair by boosting specific cell signals.

This study identified 295 genes with differential expression in Yangtze River Delta White Goats that produce high-quality brush hair, suggesting these genes and the MAPK signaling pathway may influence hair quality traits.

This study found that supplementing Liaoning cashmere goats with HMBi increased cashmere length while decreasing its diameter, attributed to changes in Met-related metabolites and elevated expression of genes related to the Met cycle and cell differentiation pathways such as Wnt and MAPK.

This study highlights IGF-1's role in promoting hair follicle proliferation, vascularization, and growth, suggesting its potential as a treatment target for hair loss disorders like androgenetic alopecia, though more research on delivery methods and long-term effects is needed.

In this study, Ageratum houstonianum ethanolic extract and its active component agerarin were found to promote hair growth and follicle elongation by increasing SCUBE3 expression via activation of MAPK–AP-1 signaling in human dermal papilla cells, suggesting potential therapeutic value for treating hair loss.

This study highlights the potential of stem cell-derived extracellular vesicles to treat UV-induced skin damage by modulating key signaling pathways, though challenges like EV composition variability and skin barrier penetration remain, underscoring the need for further research into optimized delivery methods for effective therapies.

This study found that Hetian sheep with higher wool density produce more and finer wool, with key genes potentially influencing their wool growth and density.

This study found that miR-432 inhibits KRT83 expression, revealing potential molecular mechanisms for the formation of curly fleece in Tan sheep and suggesting implications for understanding curly hair formation in humans.

In this study, researchers found that during zebrafish telencephalon regeneration, the lesioned hemisphere showed distinct gene expression changes and activated Wnt/β-catenin signaling early after injury, suggesting this pathway's significant role in recovery.

This study uncovered that bimatoprost, a prostaglandin analog, promotes hair growth by activating hair follicle progenitor cells through two pathways: the PTGFR-MAPK signaling axis and an unexpected IGF1R-PCAD-AKT signaling axis, suggesting new potential targets for treating hair disorders.

This computational study developed a regulatory model linking key genes and miRNAs to cardiac senescence, validated by connecting 94% of these elements to existing cardiac aging research.

This study reports that milk goats exhibit significantly more differentially expressed genes related to hair follicle cycling across different months compared to cashmere goats, especially in December.

This study found that arctiin, a compound from Arctium lappa, demonstrated protective effects against oxidative stress-induced dysfunction in human hair dermal papilla cells, suggesting potential therapeutic use for alopecia.

In this preclinical study, PA-011 derived from Periplaneta americana showed significant hair regrowth effects in androgenetic alopecia mouse models by inhibiting inflammation and oxidative stress, activating hair follicle stem cell proliferation, and normalizing skin microbiota, suggesting promise as an AGA treatment.

In this study, researchers identified significant differences in lipid composition between grey and black hair follicles in women with type 2 diabetes and healthy controls, suggesting these lipids may contribute to the production of grey hair and may offer targets for anti-grey-hair treatments.

This study observed that topical application of maslinic acid stimulated hair growth in mice comparably to minoxidil, possibly through the Wnt/β-catenin pathway and involving ciliary gene activity, highlighting increased levels of trichogenic gene expression and protein levels.

This review discusses the critical role of BMP signaling in the development and regulation of skin and hair follicles and notes that further research could aid therapeutic advances; it presents no new clinical results.

This study found that vitamin C increased the survival, proliferation, and hair-regenerative potential of adipose-derived stem cells through the MAPK pathway and enhanced hair growth in mice.

This study identified four new genetic loci associated with acne risk and highlighted key pathways involved in its genetic predisposition, potentially explaining 9.4% of acne's phenotypic variance.

In this study, RNA-Seq analysis identified 2717 genes differentially expressed between anagen and telogen hair follicle stem cells in cashmere goats, potentially involving several signaling pathways in vitro.

This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.

This study found that MED1 deficiency in keratinocytes accelerates skin wound healing in young mice but delays healing in older mice, suggesting differential roles in epidermal regeneration with age.

This study established an efficient short-term culture system for human hair follicle stem cells using human fibronectin and ROCK inhibitor Y-27632, enhancing cell proliferation and stemness for potential applications in hair follicle tissue engineering.

This study found that activating CB1 receptor signaling in human hair follicles increased stem cell proliferation while reducing differentiated cell survival, suggesting CB1's role as a survival stimulus for epithelial stem cells.

This laboratory study found that activated platelet‐rich plasma supernatant enhanced hair growth signaling pathways in cultured human dermal papilla cells, suggesting potential for treating androgenic alopecia.

In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.

The study characterized the transcriptional changes in porcine SKP cells transitioning to fibroblast-like cells, indicating potential roles for specific signaling pathways in this cell fate transition.

In this study, researchers found that specific miRNAs may regulate cashmere fiber traits in goats by targeting genes related to hair follicle activities, with significant expression differences between breeds.

Keratinocyte cytokines and genetic variations influence the development of moles and skin pigmentation.