23 citations
,
February 2015 in “The American journal of pathology” This study found that the absence of sebaceous glands may be an early factor in the development of keratosis pilaris, leading to hair shaft and skin barrier abnormalities, independent of filaggrin mutations.
21 citations
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March 2018 in “American Journal Of Pathology” In this study, it was observed that NIPAL4 mutations linked to autosomal recessive congenital ichthyosis lead to abnormal skin barrier function due to cytotoxic effects disrupting lipid structure and organization, which topical treatments only partially ameliorated.
21 citations
,
April 2010 in “Veterinary Dermatology” This study documented the progression of exfoliative cutaneous lupus erythematosus in German shorthaired pointers and found generally poor responses to therapies, including immunomodulatory drugs and a TNF-α inhibitor.
11 citations
,
March 2024 in “Cell and Tissue Research” In this review, researchers summarize the methods for characterizing telocytes, outline their physiological roles and implications in diseases, and discuss potential future studies including precise markers and targeted therapies.
10 citations
,
July 2015 in “Veterinary Dermatology” This study found that noninflammatory alopecia in dogs can be caused by exposure to estradiol gel used by their owners for postmenopausal symptoms, with hair regrowth observed after minimizing exposure.
8 citations
,
February 2005 in “Veterinary dermatology” This study suggests that hair loss in Chesapeake Bay retrievers is a breed-specific syndrome characterized by unique histological features and abnormal steroid production, possibly influenced by familial factors.
4 citations
,
June 2022 in “Clinical, cosmetic and investigational dermatology” In this study, researchers introduced the Sanusi FUE Score Scale to better predict and grade the difficulty of follicular unit excision hair transplantation by accounting for diverse hair and skin types, with further validation needed.
1 citations
,
August 2019 in “Environmental Toxicology” This study observed that low-dose intrauterine exposure to finasteride alters postnatal prostate development in male and female Mongolian gerbils, showing sex-specific differences in receptor expression and tissue changes.
May 2025 in “Proceedings of the National Academy of Sciences” In this study, researchers found that the histone demethylase UTX is crucial for regulating skin differentiation through retinoic acid signaling, mainly impacting females, as males compensate with a Y-linked paralog.
August 2024 in “Veterinary Dermatology” This study reported that topical ω‐0‐acylceramide improved skin barrier function in Jack Russell Terriers with TGM1-deficient autosomal recessive congenital ichthyosis, normalizing skin pH and reducing transepidermal water loss.
December 2023 in “Clinical, cosmetic and investigational dermatology” This study found that no-shave long hair-follicular unit excision using a skin-responsive device, without recess-tipped punches, yielded low graft transection and shaft break rates, improved procedure speed, and increased surgeon willingness.
This study observed that intrauterine and early postnatal exposure to finasteride affected prostatic development in Mongolian gerbils, with significant sex-based differences, particularly higher alterations in female prostates.
January 2015 in “International Journal of Pharma and Bio Sciences” This review discusses the traditional medicinal uses of Tridax procumbens, attributing its therapeutic properties to various active phytochemicals, but reports no new clinical findings.
August 2004 in “Veterinary Dermatology” This study found that hair loss in Chesapeake Bay retrievers may be related to abnormal production of adrenal sex hormones, with further research needed to explore its heritability and treatment options.
October 2010 in “Reproductive Biomedicine Online” Women with pituitary adenomas often have reproductive issues, like irregular periods and trouble getting pregnant, but not always breast milk production without pregnancy.
3 citations
,
November 2020 in “Ciencia Tecnología y Salud” This review describes the signs, symptoms, and complications of COVID-19, noting that symptoms often overlap with common and non-specific features, especially in older adults and in different stages of illness.
3 citations
,
December 2018 in “Journal of Pakistan Association of Dermatology” This study found that patients with alopecia areata often presented with multilocular patches, common scalp involvement, and associated conditions like atopic dermatitis; the disease predominantly affected younger individuals.
January 2006 in “Seibutsu Butsuri” Curly and straight hair differ in how their internal fibers are arranged.
143 citations
,
August 1991 in “Endocrinology” This study found that blocking androgen receptors inhibits testicular descent in rats more effectively during the early stages of gubernacular outgrowth than inhibiting 5a-reductase.
117 citations
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August 2008 in “Sociology of Health and Illness” This review analyzes how the pharmaceutical industry's emphasis on lifestyle drugs and marketing practices leads to the integration of pharmaceuticals into everyday life, with a domestic focus and view of drugs as quick solutions.
66 citations
,
February 2015 in “Cell & tissue research/Cell and tissue research” This review explores the mechanisms of hair cell death due to factors like noise, ototoxic drugs, and aging and reports no conclusive clinical results; ongoing research may eventually enable preventive treatments for hearing loss.
47 citations
,
January 2017 in “RSC Advances” Keratin peptides can change hair shape gently without harsh chemicals.
40 citations
,
January 2013 in “Journal of Korean Medical Science” This study found that serum ferritin levels were lower in premenopausal women with female pattern hair loss compared to healthy controls, suggesting a potential role for iron in hair loss.
36 citations
,
June 2009 in “Nanomedicine” This study found that fullerene nanomaterials can significantly enhance hair growth and increase hair follicle numbers in both shaved and bald mouse models, as well as in cultured human skin sections.
15 citations
,
October 2010 in “International Journal of Dermatology” Women with AGA have higher lipid levels, increasing heart disease risk.
14 citations
,
May 2008 in “Journal of proteome research” This study found that dutasteride reduced β-amyloid plaque load in a cerebral amyloidosis model, seemingly linked to mitochondrial apoptosis and autophagy processes.
12 citations
,
December 2017 in “Journal of biomaterials science. Polymer ed.” This study found that protein extracts from human hair demonstrated significant antioxidant abilities, protecting human dermal fibroblasts from oxidative stress, suggesting potential for biomedical applications.
10 citations
,
January 2016 in “PLOS ONE” This study investigated protein expression changes during mouse hair follicle cycles and suggested their involvement in biological networks, potentially identifying targets for hair disease therapy.
6 citations
,
June 2011 in “British Journal of Dermatology” This study found that individuals with alopecia areata had significantly higher serum levels of retinol-binding protein 4 and increased IgG immunoreactivity against it, suggesting a role in the disease's pathogenesis.
4 citations
,
January 2017 in “Ciência Rural” This case report highlights that equine multisystemic eosinophilic epitheliotropic disease should be considered in horses presenting with skin lesions and gastrointestinal symptoms, as illustrated by the progression in a 5-year-old horse despite treatment.