22 citations
,
March 2021 in “European journal of endocrinology” This source provides a comprehensive review of the causes, diagnostics, and management of primary amenorrhea in pediatric endocrinology and gynecology, emphasizing that with early and accurate diagnosis, fertility may be achievable even when a cure is not available.
22 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This study found that injecting autologous dermal sheath cup cells significantly increased hair density and diameter in male and female pattern hair loss compared to a placebo for up to 9 months.
22 citations
,
November 2017 in “Scientific Reports” This study found that, despite a major depletion of SOX2-expressing stem cells in the pituitary, there was no effect on endocrine cell homeostasis or response to certain stressors in adult mice.
22 citations
,
December 2016 in “Journal of Pakistan Association of Dermatologists” This review discusses dermatologic changes in chronic renal failure patients undergoing hemodialysis and reports no new clinical results.
22 citations
,
January 2015 in “Dermatology Research and Practice” This study found that an oral marine protein supplement significantly increased hair growth and reduced hair shedding in women with temporary thinning hair over 90 days compared to a placebo.
22 citations
,
November 2014 in “Proteins Structure Function and Bioinformatics” In this study, researchers mapped cysteine accessibility in wool keratins and KAPs, revealing that certain cysteines in keratin end domains and Types I and II rod domains are accessible and likely involved in forming disulfide bonds.
22 citations
,
July 2011 in “EFSA journal” There is not enough evidence to support health claims about soy isoflavones.
22 citations
,
April 2010 in “Journal of Cellular Biochemistry” This study concluded that the hairless protein interacts with the vitamin D receptor to repress transcription crucial for hair cycling, employing multiple protein interfaces and modulating chromatin structure.
22 citations
,
July 2003 in “PubMed” This study reported that finasteride 1 mg significantly improved hair growth in men aged 41 to 60 with predominantly vertex male pattern hair loss over 24 months compared to placebo.
22 citations
,
May 2002 in “Skin Research and Technology” This study found that in male androgenetic alopecia, the contrast enhanced phototrichogram technique was superior in detecting changes in hair density and thickness compared to other methods.
22 citations
,
May 2000 in “American Journal of Clinical Dermatology” This review discusses treatment options for androgenetic alopecia in men and women, highlighting minoxidil and finasteride, without presenting new clinical findings.
22 citations
,
August 1999 in “Mechanisms of Development” This study identified two novel genes, pmg-1 and pmg-2, expressed in various skin and gland tissues and potentially involved in the differentiation of epithelial cells in epidermal appendages.
21 citations
,
January 2020 in “Conservation Physiology” This study found that cortisol concentrations were significantly higher in hair samples with follicles compared to those without, suggesting potential confounding in stress assessments using different hair sampling methods.
21 citations
,
September 2019 in “International Journal of Nanomedicine” RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
21 citations
,
July 2019 in “Cardiovascular Research” This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.
21 citations
,
May 2016 in “Experimental and Therapeutic Medicine” In this study, the researchers observed that MMP-2 and MMP-9 significantly fluctuated with the hair growth cycle in mice, suggesting their important role in hair development.
21 citations
,
December 2013 in “Archives of Dermatological Research” No link found between new male baldness genes and female hair loss.
21 citations
,
January 2013 in “Clinical Endoscopy” This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.
21 citations
,
September 2008 in “Magnetic Resonance Imaging” This study utilized magnetic resonance imaging to noninvasively visualize and differentiate skin structures in rat skin, finding a significant correlation between MRI data and histological areas.
21 citations
,
August 2024 in “Journal of Clinical Medicine” This review highlights that malnutrition, including deficiencies in proteins and micronutrients, may exacerbate allergic conditions like dermatitis and asthma by promoting inflammation, while adequate micronutrient intake supports regulatory immune responses.
21 citations
,
May 2024 in “American Journal of Medical Genetics Part A” This study observed that among patients with Myhre syndrome, those with the SMAD4 gene variant p.Arg496Cys experienced fewer symptoms like hearing loss, while those with the p.Ile500Thr variant often had severe aortic hypoplasia, highlighting the diverse symptom progression and genetic factors of this rare condition.
21 citations
,
November 2020 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that low massage frequencies like 4.2 Hz enhance nanoparticle penetration into hair follicles more effectively than higher frequencies, indicating potential applications in therapeutic and cosmetic delivery.
21 citations
,
June 2017 in “Journal of Dermatological Treatment” This study found that topical cetirizine 1% significantly improved hair density and diameter in patients with androgenetic alopecia, with patients tolerating the treatment well.
21 citations
,
June 2016 in “Journal of Medical Primatology” This study observed that management practices affect alopecia and hair cortisol in captive rhesus monkeys, with variations in these effects between different facilities.
21 citations
,
October 2015 in “Current Drug Targets” This review discusses the comparative efficacy of dutasteride and finasteride for benign prostatic hyperplasia, reporting that while symptom improvements are similar, dutasteride may reduce prostate surgery risk and acute urinary retention more effectively.
21 citations
,
January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.
21 citations
,
April 2011 in “Clinical Cosmetic and Investigational Dermatology” This review discusses treatments for acne of varying severity and hormonal influences but reports no new clinical results; it suggests specific therapies for different acne types and highlights considerations for female patients.
21 citations
,
October 2009 in “Dermatology” This study found that male pattern hair loss may be associated with differences in serum levels of androstenedione, cortisol, 17 beta-estradiol, and luteinizing hormone, compared to controls.
21 citations
,
June 2009 in “Current Medical Research and Opinion” In this study, men seeking treatment for male pattern hair loss were highly concerned about their condition and had often attempted self-treatment, but many were dissatisfied with their physician consultations due to unmet expectations and perceived indifference from doctors.
21 citations
,
June 2009 in “Mammalian genome” This study describes a mouse model for Marie Unna Hereditary Hypotrichosis, identifying mutations in the hairless gene that result in sparse or absent hair and cyst-like hair follicles.