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research Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein
This study found that androgen binding in male rat livers involves specific androgen receptors, which decrease with castration and are inducible in female livers with testosterone.
research Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing
research Hair Cortisol Concentration in Healthy Children and Adolescents Is Related to Puberty, Age, Gender, and Body Mass Index
This study found that gender, puberty, and BMI significantly affect hair cortisol concentrations in children, suggesting these factors should be considered in future research.
research HPA axis stress reactivity and hair cortisol concentrations in recently detoxified alcoholics and healthy controls with and without childhood maltreatment
This study found that alcohol dependence is associated with altered HPA axis functioning, with AD patients showing higher hair cortisol concentrations and reduced ACTH and cortisol levels, irrespective of childhood maltreatment history.
research Dermatophytosis and papular eosinophilic/mastocytic dermatitis (urticaria pigmentosa-like dermatitis) in three Devon Rex cats
This case report describes three Devon Rex cats with papular dermatitis due to dermatophytosis, which resolved with antifungal treatment.
research The latest options and future agents for treating male hypogonadism
This review discusses developments in testosterone therapy, including the shift towards transdermal therapies and long-acting injectables, but reports no new clinical findings; emerging therapies are in development.
research Nucleation and growth of macrofibrils in trichocyte (hard-α) keratins
This study suggests that varying intersheet interactions may explain the differences between the two polymorphic forms of macrofibril assembly in Merino wool and hair.
research Dose-response study of topical minoxidil in male pattern alopecia
This study found that 1% and 2% topical minoxidil solutions resulted in clinically noticeable hair growth compared to lower doses or placebo in men with male pattern baldness.
research Management of the psychological comorbidities of dermatological conditions: practitioners' guidelines
This review discusses the importance of recognizing and treating psychiatric conditions in dermatology patients, offering practical recommendations for dermatologists to manage psychocutaneous diseases effectively, but reports no new clinical results.
research New CDH3 mutation in the first Spanish case of hypotrichosis with juvenile macular dystrophy, a case report
This study presents the first reported Spanish case of Hypotrichosis with Juvenile Macular Dystrophy, identifying a new CDH3 mutation and highlighting the importance of clinical and genetic evaluation for accurate diagnosis.
research Male hormonal contraception: looking back and moving forward
This review discusses the physiological basis, history, and current development of male hormonal contraception, highlighting its potential risks and benefits, but reports no new research findings.
research Management of hypotrichosis of the eyelashes: Focus on bimatoprost
This review discusses the cutaneous application of bimatoprost ophthalmic solution 0.03% for enhancing upper eyelash growth and suggests it is both safe and effective; no new clinical results are reported.
research Alopecia in Rhesus macaques correlates with immunophenotypic alterations in dermal inflammatory infiltrates consistent with hypersensitivity etiology
This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.
research Advances in male hormone substitution therapy
This review examines the benefits and potential risks of androgen replacement therapy for male hypogonadism but reports no new clinical results; the authors highlight the need for careful risk assessment, especially in older men.
research Hypertrichosis of vellus hairs of the malar region after unilateral treatment with bimatoprost
This case report found that topical bimatoprost usage in a female Hispanic patient with open-angle glaucoma was associated with hypertrichosis and increased pigmentation of vellus hairs on the malar region.
research The Growth Factors in Advanced Platelet-Rich Fibrin (A-PRF) Reduce Postoperative Complications after Mandibular Third Molar Odontectomy
This study found that advanced platelet-rich fibrin (A-PRF) reduced postoperative complications like pain, trismus, and edema following mandibular wisdom teeth removal.
research Characterization ofCDH3-Related Congenital Hypotrichosis With Juvenile Macular Dystrophy
This study observed that CDH3-related congenital hypotrichosis with juvenile macular dystrophy presents with childhood-onset progressive chorioretinal atrophy and universally thin and sparse scalp hair.
research Alopecia as a rare but distinct manifestation of pemphigus vulgaris
This study observed that in pemphigus vulgaris patients, hair loss and alopecic patches may result from anti-desmoglein autoantibody-mediated acantholysis and inflammatory changes, leading to non-scarring alopecia with potential for regrowth after treatment.
research Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development
This study found that exposure to sex steroid biosynthesis inhibitors increases the expression of piRNA pathway genes in frog larvae, suggesting these genes play a role in gonadal sex differentiation.
research Alopecia androgénica masculina y factores de riesgo cardiovascular: estudio de casos y controles
In this study, early-onset androgenetic alopecia in men was associated with a higher prevalence of metabolic syndrome and carotid atherosclerosis compared to controls, suggesting cardiovascular screening might be beneficial for this group.
research Treatment of Male Pattern Alopecia Using Topical Minoxidil in The Netherlands
This study found that 2% minoxidil solution was about three times more effective than a placebo in improving hair growth in men with early male pattern alopecia over 24 weeks.
research 3D bioprinting of engineered exosomes secreted from M2-polarized macrophages through immunomodulatory biomaterial promotes in vivo wound healing and angiogenesis
This study found that 3D-printed polyamine-modified hydrogels facilitate M2 macrophage polarization and exosome secretion, enhancing skin cell compatibility and promoting wound healing and hair follicle induction in an animal model through specific signaling pathways, suggesting potential for skin disorder therapies.
research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa
This study found that monocytes/macrophages with a pro-inflammatory M1-like phenotype may play a crucial role in the pathogenesis of hidradenitis suppurativa, suggesting potential therapeutic targets.
research Predictive Metagenomic Profiling, Urine Metabolomics, and Human Marker Gene Expression as an Integrated Approach to Study Alopecia Areata
This study found significant differences in scalp microbiome composition and volatile organic metabolites between individuals with alopecia areata and healthy controls, suggesting potential microbiome-related therapeutic interventions for hair growth disorders.
research Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias
This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.
research Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry
This study developed and validated a mass spectrometric method to measure hydroxy-androgens in serum, which aids in understanding androgen synthesis in castration resistant prostate cancer.
research ILK modulates epithelial polarity and matrix formation in hair follicles
This study found that ILK deficiency disrupts hair follicle development by impairing cell polarity and laminin-511 assembly, but these defects can be partially reversed with exogenous laminin-511.
research Miniaturized hairs maintain contact with the arrector pili muscle in alopecia areata but not in androgenetic alopecia: A model for reversible miniaturization and potential for hair regrowth
This study found that loss of contact between the arrector pili muscle and the hair follicle bulge may explain why hair loss in male and female pattern baldness is largely irreversible, unlike in alopecia areata.
research Managing Cutaneous Manifestations of Hyperandrogenic Disorders
This review examines the role of androgens in cutaneous disorders and the potential therapeutic effects of different oral contraceptives, noting variations in individual responses and the influence of genetic and local factors but reports no new clinical results.