18 citations
,
November 2012 in “Australasian Journal of Dermatology” This case report describes a 66-year-old man with frontal fibrosing alopecia, a rare lichen planopilaris variant, presenting with scarring alopecia at the hairline and extensive body hair loss.
18 citations
,
October 2012 in “Dermatologic Clinics” This article discusses primary cicatricial alopecias, a group of rare inflammatory scalp disorders resulting in permanent hair loss, and reports no new findings.
18 citations
,
May 2006 in “Journal of Cutaneous Medicine and Surgery” This study reports the first known case of linear lichen planopilaris following Blaschko's lines in a nonfacial region.
17 citations
,
November 2018 in “Dermatology” The authors concluded that Hispanic/Latino ethnicity, facial papules, and premenopausal status in patients with frontal fibrosing alopecia may indicate a susceptibility to more severe disease, potentially necessitating early treatment.
16 citations
,
January 2019 in “Neuropsychobiology” This study found that individuals with lichen planopilaris reported lower quality of life and self-esteem and higher depression scores compared to healthy controls.
16 citations
,
June 2015 in “Pediatric dermatology” This review discusses lichen planopilaris in children and highlights its rarity, potential for misdiagnosis, and need for suspicion in atypical or treatment-resistant alopecia cases, but reports no new results.
16 citations
,
February 2020 in “The Laryngoscope” This study found that hair transplantation is feasible in patients with lichen planopilaris and frontal fibrosing alopecia, but outcomes are generally less favorable compared to other causes and these diseases may also develop after the procedure.
16 citations
,
December 2017 in “Journal of The American Academy of Dermatology” This study found that low-level laser therapy may reduce inflammation and increase hair thickness in patients with lichen planopilaris after six months of treatment, though the small sample size limits the findings.
16 citations
,
April 2014 in “Dermatologic Clinics” Dermatoscopy helps diagnose hair and scalp disorders in people with Afro-textured hair, but more research is needed for better understanding and treatment.
16 citations
,
February 2010 in “Journal of the European Academy of Dermatology and Venereology” This article is a letter to the editor about fibrosing alopecia in a pattern distribution and reports no new research findings.
14 citations
,
January 2018 in “Skin Appendage Disorders” This case report suggests that identifying hyperpigmentation on the upper eyelid with specific dermoscopy patterns could help diagnose facial lichen planus pigmentosus without needing a facial biopsy.
14 citations
,
January 2015 in “Skin appendage disorders” This study reports that subtle presentations of lichen planopilaris may be mistaken for seborrheic dermatitis in patients with androgenetic alopecia, highlighting the importance of dermatoscopy-guided biopsy for accurate diagnosis.
14 citations
,
March 2014 in “Journal of the Society of Cosmetic Scientists of Korea” This study suggests that ethanol extracts from ten selected Korean herb medicines reduced inflammatory markers in a cell model and did not cause skin irritation in human testing, indicating potential cosmetic use for irritation prevention.
13 citations
,
August 2020 in “Mayo Clinic proceedings” In this study, women with lichen planopilaris were found to have high rates of thyroid disease, depression, and anxiety, and about half experienced slowed or stabilized disease progression with treatment.
13 citations
,
September 2017 in “Skin appendage disorders” Some women with Frontal Fibrosing Alopecia also have Lichen Planopilaris, which can lead to more symptoms and affect hair outside the scalp.
13 citations
,
April 2018 in “Journal of The American Academy of Dermatology” This study found that 64.8% of patients with different types of alopecia had vitamin D deficiency, and those with lichen planopilaris and telogen effluvium had higher odds of severe deficiency compared to patients with alopecia areata.
12 citations
,
June 2020 in “Journal of The American Academy of Dermatology” This article discusses platelet-rich plasma therapy for cicatricial alopecias like lichen planopilaris and reports no confirmed new clinical results; the authors highlight ongoing uncertainty about its effectiveness and potential risks.
12 citations
,
December 2016 in “Medical Hypotheses” This research suggests that the enzyme Phospholipase D from E. coli is a strong candidate as the underlying cause of benign prostatic hyperplasia, potentially mediated by its conversion to lysophosphatidic acid in the prostate.
12 citations
,
December 2016 in “The FASEB Journal” This study found that the absence of vitamin D receptor-mediated suppression of PPARγ expression causes hair loss in VDR-null mice.
12 citations
,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” This case report describes a 67-year-old woman with frontal fibrosing alopecia and her daughter with lichen planopilaris, noting identical HLA D types which suggest a phenotypical link between these conditions.
11 citations
,
May 2011 in “Journal of Cutaneous Medicine and Surgery” This report describes a case of lichen planopilaris potentially triggered by chronic scalp trauma from break dancing, emphasizing the need for careful examination to differentiate it from androgenetic alopecia.
11 citations
,
February 2020 in “Dermatology and therapy” This study reported that four patients with lichen planopilaris showed dramatic improvement, including symptom reduction and hair regrowth, after treatment with low-level light therapy.
11 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a missense mutation in the keratin 71 gene as the cause of autosomal dominant woolly hair/hypotrichosis in a Japanese family, marking the first human mutation in KRT71 linked to a hair disorder.
11 citations
,
April 2012 in “Journal of Investigative Dermatology” A specific mutation in PA-PLA1α causes abnormal hair growth.
9 citations
,
February 2025 in “Journal of Nanobiotechnology” In this study, researchers found that using bioinspired nanovesicles derived from inflammation memory-activated epidermal stem cells effectively promoted healing in diabetic wounds by reprogramming neutrophils to an anti-inflammatory phenotype in both laboratory and animal models.
9 citations
,
May 2021 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study suggests that topical minoxidil may be a promising treatment for isolated autosomal recessive woolly hair due to LIPH mutations, although effective treatments are not yet established.
9 citations
,
September 2018 in “JAAD Case Reports” This article describes a unique case of lichen planopilaris with a previously unreported trigger in one of the youngest documented adult patients, without providing new clinical results or data.
9 citations
,
September 2016 in “Dermatologic Surgery” This study identified a new subtype of lichen planopilaris that mimics androgenetic alopecia, selectively affecting vellus hair follicles and presenting unique histopathological features.
9 citations
,
January 2015 in “Current problems in dermatology” This review highlights recent genetic research advancements in understanding hereditary hair diseases but reports no new study results, emphasizing the identification of genes related to both monogenic and polygenic hair disorders.
9 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This article reviews nonscarring and scarring hair loss conditions that may mimic androgenetic alopecia, reporting no new clinical results and highlighting the need for accurate diagnosis in hair restoration surgery.