33 citations
,
December 2014 in “Journal of the European Academy of Dermatology and Venereology” This study found that lichen planus in Taiwanese patients is associated with several autoimmune diseases, including systemic lupus erythematosus, Sjögren's syndrome, and alopecia areata, with some gender-specific variations in associations.
33 citations
,
October 2013 in “Journal of The American Academy of Dermatology” In this study, pioglitazone treatment in patients with lichen planopilaris showed limited success, with significant improvement seen in only a minority of cases.
33 citations
,
April 2012 in “British Journal of Dermatology” This review discusses the role of stem cells in alopecia pathogenesis, highlighting the differences between scarring and nonscarring types, and reports no new clinical results.
30 citations
,
January 2020 in “Journal of The American Academy of Dermatology” This review reports no new clinical results but discusses fibrosing alopecia in a pattern distribution as a distinct scarring alopecia with characteristics of both androgenetic alopecia and lichen planopilaris.
30 citations
,
December 2017 in “Journal of The American Academy of Dermatology” This correspondence discusses proposed updates to the diagnostic criteria for frontal fibrosing alopecia, emphasizing the importance of differentiating it from other types of alopecia.
30 citations
,
November 2013 in “Journal of The American Academy of Dermatology” This study reported that patterns of fibrosis identified through elastin staining may help distinguish specific forms of primary cicatricial alopecia in biopsy specimens, with certain patterns suggesting particular diagnoses.
29 citations
,
February 2016 in “International Journal of Dermatology” This study found that patients with lichen planus were significantly more likely to have dyslipidemia, particularly with higher triglyceride levels.
28 citations
,
July 2015 in “American Journal of Clinical Dermatology” This study found a higher prevalence of metabolic syndrome in patients with lichen planus, especially those with mucosal involvement, which is associated with increased cardiovascular and diabetes risk.
28 citations
,
August 2018 in “Dermatologic Surgery” This abstract is a listing of affiliations and funding, with no new study or results reported.
28 citations
,
November 2017 in “Skin appendage disorders” This paper proposes a systematic approach to evaluating scalp itch using the SCALLP acronym and highlights the importance of classifying cases based on the presence of dermatological lesions and hair loss, but it reports no new clinical findings.
27 citations
,
January 2015 in “Current problems in dermatology” This article reviews various types of scarring alopecia, detailing their inflammatory characteristics, but presents no new clinical findings.
26 citations
,
December 2020 in “Photodermatology Photoimmunology & Photomedicine” This review discusses photobiomodulation as a potential treatment for hair loss, highlighting its safety and possible effectiveness but noting cost, protocol standardization, and expectation management as limitations; it reports no new clinical results.
26 citations
,
April 1999 in “Dermatologic Clinics” This article reviews the basics of hair follicle biology, laser/tissue interactions, and hirsutism and hypertrichosis causes, discussing the long-pulsed alexandrite laser's role in hair reduction without reporting new clinical results.
25 citations
,
December 2018 in “Human Molecular Genetics” This study found that the PSEN1-P242LfsX11 mutation in hidradenitis suppurativa influences cytokine and chemokine expression in macrophages, potentially affecting inflammatory responses.
24 citations
,
December 2018 in “Life sciences” This review discusses the role of lysophosphatidic acid in skin physiology and pathology, highlighting its significance in processes like wound healing and hair follicle development, but reports no new clinical findings.
24 citations
,
July 2015 in “Molecular Medicine Reports” This study found that lysophosphatidic acid increases mesenchymal stem cell proliferation and migration through signaling pathways and reactive oxygen species, implicating potential applications in stem cell expansion.
23 citations
,
April 2018 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses the classification and diagnosis of primary cicatricial alopecias and reports no new clinical results; it highlights the need for effective treatments owing to limited evidence of current therapies' efficacy.
23 citations
,
May 2017 in “Journal of the American Academy of Dermatology” This study found that patients with frontal fibrosing alopecia had lower epidermal melanocyte counts and reduced epidermal thickness compared to lichen planopilaris patients and controls, suggesting a link with hypopigmentation.
23 citations
,
January 2010 in “Journal of The American Academy of Dermatology” This article discusses the efficacy and safety of mycophenolate mofetil and hydroxychloroquine for treating lichen planopilaris and reports no new clinical results.
22 citations
,
January 2018 in “Experimental Dermatology” This article reviews insights into the pathogenesis of primary cicatricial alopecias, such as lichen planopilaris, provided by emerging technologies, but it does not report new clinical results.
22 citations
,
July 2017 in “Australasian journal of dermatology” This study reported that two Chinese patients with lichen planopilaris or frontal fibrosing alopecia experienced satisfactory hair regrowth for 3-4 years following follicular unit extraction hair transplantation after their conditions were stabilized with therapy.
22 citations
,
January 2017 in “Skin appendage disorders” This research analyzed 72 primary scarring alopecia cases in a Barcelona hospital, finding that the majority involved women, with a lymphocytic infiltrate and subacute onset in many cases, leading to stable disease, while neutrophilic cases had more acute episodes.
22 citations
,
April 2013 in “International Journal of Dermatology” Frontal fibrosing alopecia can occur with lichen planus pigmentosus, needing careful diagnosis and treatment.
22 citations
,
June 2012 in “PLOS ONE” In this study, researchers found that impaired cholesterol biosynthesis in hair follicles may trigger an inflammatory immune response linked to primary cicatricial alopecia, providing new insights into the disorder's pathogenesis.
22 citations
,
April 2011 in “Anais Brasileiros de Dermatologia” This report describes two cases where lichen planopilaris may have compromised the hair follicles in both donor and recipient areas following follicular unit transplantation.
21 citations
,
September 2018 in “International journal of women’s dermatology” In this study, patients with lichen planopilaris showed higher prevalence of autoimmune disorders like Hashimoto's thyroiditis and hypothyroidism compared to those with seborrheic dermatitis.
20 citations
,
May 2016 in “Journal of Cutaneous Pathology” This study suggests that the presence and arrangement of plasmacytoid dendritic cells can help distinguish chronic cutaneous lupus erythematosus from other types of scarring alopecia.
20 citations
,
January 2015 in “Biochimica and biophysica acta. Molecular and cell biology of lipids” This review discusses lysophosphatidic acid's role in neuropathic pain and cholestatic itch, highlighting its complex signaling pathways, but reports no new clinical results.
19 citations
,
April 2018 in “International Journal of Dermatology” This study found that female patients with frontal fibrosing alopecia are significantly more likely to have systemic lupus erythematosus compared to controls.
19 citations
,
July 2017 in “Clinical and experimental dermatology” This study provides one of the first descriptions of the demographic, clinical, and therapeutic characteristics of lichen planopilaris in Chilean adults, reporting that treatment usually reduced or halted disease progression.