April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.
April 2018 in “Journal of Investigative Dermatology” This study found that the cell of origin in mouse skin affects melanoma phenotype and response to therapies, despite the presence of the same genetic mutations.
February 2018 in “Journal of Aesthetic Nursing” This editorial emphasizes the critical need for laser protection supervisors in the aesthetic sector due to a rise in laser-related claims attributed to inadequate training and safety protocol adherence, highlighting that better understanding and supervision can help mitigate risks.
January 2018 in “Hair transplant forum international” This study explores the use of low-dose naltrexone as a novel treatment for lichen planopilaris, but specific results or outcomes are not detailed in the abstract.
January 2018 in “Skin appendage disorders” A woman's hair loss was correctly diagnosed as Lichen planopilaris after initial misdiagnosis, highlighting the usefulness of trichoscopy in diagnosing hair disorders.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that N-acetyl-GED may protect and partially rescue human hair follicles from experimentally-induced epithelial-mesenchymal transition ex vivo, suggesting its potential in treating scarring alopecias like lichen planopilaris.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the loss of Langerhans cells in lichen planopilaris scars may be linked to the downregulation of ITG αvβ6, which is not seen in other scar formation diseases.
April 2017 in “Australasian Journal of Dermatology” This study observed that systemic acitretin improved symptoms in 75% of lichen planopilaris patients, despite varied responses and a dominant female prevalence.
April 2017 in “Journal of Investigative Dermatology” This study reports a new optimized protocol for isolating and labeling single cells from neonatal mouse skin, enabling high-quality single cell RNA sequencing for lineage-specific cell analysis.
April 2017 in “Journal of Investigative Dermatology” This study identified that in mice, sweat gland development is directed by mesenchymal signals that suppress SHH-production, while in humans, this occurs through a BMP spike in embryonic development.
April 2017 in “Journal of Investigative Dermatology” In this pilot study, researchers observed a correlation between clinical severity and histologic severity of lichen planopilaris, suggesting that an immunohistochemical scoring system could aid in grading disease activity.
April 2016 in “Journal of The American Academy of Dermatology” People with lichen planopilaris often have seborrheic dermatitis, which can delay the diagnosis of lichen planopilaris.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the occipital scalp had significantly higher epidermal nerve fiber density than the frontoparietal scalp, which may explain increased sensitivity in some patients.
July 2015 in “Journal of the Dermatology Nurses’ Association” This review covers the clinical presentation and challenges in treating frontal fibrosing alopecia in postmenopausal women and concludes that more research is needed to understand its etiology and develop effective treatments.
May 2015 in “Journal of The American Academy of Dermatology” This study found that oral minoxidil 5 mg daily significantly improves hair growth in men with male pattern hair loss, demonstrating safety with minor side effects such as hypertrichosis and pedal edema.
January 2015 in “Hair transplant forum international” Up to 10% of hair loss patients might have early signs of a condition called Lichen Planopilaris.
May 2014 in “Clinical and Experimental Dermatology” A 70-year-old woman with a rare skin condition improved after treatment with topical steroids and acitretin.
March 2014 in “Journal of The American Academy of Dermatology” Mycophenolic acid may help hair growth, a combination treatment improves hair thickness in male hair loss, and early treatment of frontal fibrosing alopecia is important.
December 2013 in “Research Portal (King's College London)” This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.
September 2013 in “Hair transplant forum international” This abstract describes frontal fibrosing alopecia, a type of cicatricial alopecia identified in post-menopausal women, and reports no new clinical findings.
This review discusses various skin-related conditions affecting hair and nails, highlighting associations with systemic pathologies but reports no new clinical findings.
February 2013 in “Journal of the American Academy of Dermatology” This case report found that intense focused skin tightening ultrasound reduced excessive underarm sweating by nearly 80% in two patients and was associated with temporary side effects like tenderness and redness.
January 2013 in “Refubium (Universitätsbibliothek der Freien Universität Berlin)” This study observed that hormone replacement therapy and autoimmune diseases may be more common among women with frontal fibrosing alopecia compared to those with androgenetic alopecia.
April 2012 in “Encyclopedia of Life Sciences” This review discusses recent genome-wide association studies identifying novel candidate genes for various forms of alopecia, providing insights into their pathogenesis and molecular mechanisms, but reports no new clinical results.
April 2012 in “Informa Healthcare eBooks” Fibrosing alopecia in a pattern distribution is a unique hair loss condition with inflammation and scarring, resembling but distinct from common balding.
This report describes two cases where lichen planopilaris compromised hair follicles in both donor and recipient areas after follicular unit transplantation, emphasizing the need for a biopsy if lichen planopilaris is suspected.
This study identified several genetic mutations linked to hereditary skin and hair disorders in consanguineous families from remote areas of Pakistan, enhancing understanding of the molecular basis of these conditions.
January 2005 in “Life sciences” This review discusses the pathophysiologic role of lysophosphatidic acid in the skin and reports no clinical results, suggesting pharmacological inhibition as a potential treatment for various skin disorders.
January 2000 in “Acta Academiae Medicine Militaris Tertiae” This study found that the distribution of hair keratin family proteins varies in normal scalp hair follicles, which may aid in identifying the origin of hair neoplasms.
July 1998 in “Proceedings of SPIE” This study found that Low Power Laser therapy may be an effective complementary treatment for scalp alopecia and crural ulcers, showing quicker and potentially better results than conventional treatments.