10 citations,
April 2016 in “Research and reports in transdermal drug delivery” Transfollicular drug delivery is promising but needs more research to improve and understand it better.
3 citations,
October 2022 in “International Journal of Impotence Research” Testosterone Replacement Therapy can improve sexual health in postmenopausal women with low sexual desire, but more research is needed on its long-term effects.
39 citations,
November 2021 in “Clinical Endocrinology” Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
1 citations,
July 2023 in “F&S Reviews” Some common medications may harm male fertility by affecting hormones, sperm production, and sexual function.
20 citations,
April 2021 in “Journal of Womens Health” Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.
August 2023 in “Journal of Clinical Medicine” Metformin lowers prolactin in women without PCOS but not in those with PCOS, where it reduces other hormones instead.
90 citations,
December 2007 in “Current Oncology” Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.
50 citations,
May 2018 in “International journal of cardiology” Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.
36 citations,
October 2021 in “Frontiers in Endocrinology” Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
8 citations,
February 2021 in “Journal of the American Heart Association” Medical castration in prostate cancer patients can increase the risk of serious heart rhythm problems, so it's important to monitor heart activity during treatment.
6 citations,
December 2022 in “Frontiers in Pharmacology” Quercetin may help improve symptoms of polycystic ovary syndrome.
219 citations,
January 2006 in “Drug Metabolism Reviews” DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
3 citations,
May 2023 in “Biomedicines” PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.
3 citations,
June 2017 in “Reproductive biomedicine online” A certain mutation in the fetal alpha 5-reductase gene is linked to a higher risk of late miscarriage.
2 citations,
January 2023 in “Journal of Clinical Medicine” People with hair loss conditions may also have thyroid disorders, but more research is needed to understand the connection.
February 2024 in “Clinical, Cosmetic and Investigational Dermatology” Certain fats in the blood are linked to an increased risk of male pattern baldness.
January 2022 in “IntechOpen eBooks” Some lesser-known causes of PCOS include autoimmune issues, genetic mutations, and changes in the body's microbiome.
18 citations,
October 2017 in “PLOS ONE” The study concluded that similar pathways regulate hair growth in dogs and mice, and these pathways are disrupted in dogs with Alopecia X, affecting stem cells and hormone metabolism.
12 citations,
July 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with hormonal imbalances similar to PCOS may have increased risk of metabolic and heart diseases.
5 citations,
January 2017 in “Acta Endocrinologica” High androgen levels in postmenopausal women may suggest an ovarian tumor, and removing it can improve heart and metabolic health.
1 citations,
May 2023 in “Cell reports medicine” Sons of mothers with polycystic ovary syndrome (PCOS) have a higher risk of obesity and insulin resistance, possibly due to certain genes and factors passed down from their mothers.
112 citations,
April 2009 in “Cochrane library” Spironolactone may reduce excessive hair growth in women but its effectiveness for acne is not supported.
54 citations,
October 2010 in “Clinics in dermatology” Diet, especially dairy and high-sugar foods, can cause acne.
43 citations,
July 2017 in “International journal of pharmaceutics” Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
5 citations,
May 2018 in “Therapeutic advances in drug safety” Androgen use may increase the risk of stroke, but more research is needed.
66 citations,
March 1998 in “Mayo Clinic Proceedings” Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.
8 citations,
February 2022 in “Vascular Health and Risk Management” Some skin conditions may increase the risk of heart disease, and understanding their connection could lead to better treatments.
1 citations,
November 2023 in “Medicina” Hormone therapy improves mental well-being in transgender individuals but requires ongoing health monitoring.
September 2024 in “Frontiers in Neuroendocrinology” 5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.
August 2023 in “Medicina-lithuania” Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.