Search
for

    Did you mean Lipophilic Drugs?
    Glossary Lipophilic Drugs

    dissolve in fats and easily cross cell membranes

    Lipophilic drugs, also known as fat-soluble drugs, are medications that dissolve in fats, oils, and lipids rather than water. This property allows them to easily cross cell membranes, which are composed of lipid bilayers, facilitating their absorption and distribution within the body. These drugs often have longer half-lives and can accumulate in fatty tissues, potentially leading to prolonged effects or toxicity.

    Sort by

    Research 30 of 1000+

    1. Recent studies on the delivery of hydrophilic drugs in nanoparticulate systems Journal of Drug Delivery Science and Technology · 2015 · 47 citations
    2. Liposomal systems as drug delivery vehicles for dermal and transdermal applications Archives of Dermatological Research · 2011 · 151 citations
    3. Role of skin enzymes in metabolism of topical drugs Metabolism and Target Organ Damage · 2024 · 6 citations
    4. Green formulation of spironolactone loaded chitosan coated nano lipid carrier for treatment of acne vulgaris: a randomized double-blind clinical trial Advanced Pharmaceutical Bulletin · 2023 · 8 citations
    5. Nitroxide pharmaceutical development for age-related degeneration and disease Frontiers in Genetics · 2015 · 24 citations
    6. Microneedle Arrays Combined with Nanomedicine Approaches for Transdermal Delivery of Therapeutics Journal of Clinical Medicine · 2021 · 42 citations
    7. Impact of Ester Promoieties on Transdermal Delivery of Ketorolac Journal of Pharmaceutical Sciences · 2014 · 10 citations
    8. Advance and Challenges in the Treatment of Skin Diseases with the Transdermal Drug Delivery System Pharmaceutics · 2023 · 2 citations
    9. Contribution of the Hair Follicular Pathway to Total Skin Permeation of Topically Applied and Exposed Chemicals Pharmaceutics · 2016 · 39 citations
    10. Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs Pharmaceutics · 2021 · 8 citations
    11. NANOPARTICLE-EMBEDDED MICRONEEDLES FOR ENHANCED TRANSDERMAL DELIVERY: ADVANCES AND APPLICATIONS International Journal of Applied Pharmaceutics · 2026
    12. Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition Endocrine Reviews · 2005 · 451 citations
    13. Delivery and targeting of nanoparticles into hair follicles Therapeutic Delivery · 2014 · 94 citations
    14. Squalene-Containing Nanostructured Lipid Carriers Promote Percutaneous Absorption and Hair Follicle Targeting of Diphencyprone for Treating Alopecia Areata Pharmaceutical Research · 2012 · 59 citations
    15. Absorption sites of orally administered drugs in the small intestine Expert Opinion on Drug Discovery · 2017 · 55 citations
    16. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations
    17. Nanocarrier Systems for Transdermal Drug Delivery InTech eBooks · 2012 · 13 citations
    18. Recent Advances in Drug Design and Drug Discovery for Androgen- Dependent Diseases Current Medicinal Chemistry · 2016 · 11 citations
    19. Trends in Nanotechnology for Practical Applications Elsevier eBooks · 2018 · 9 citations
    20. Enhancing hair regeneration: Recent progress in tailoring nano-structured lipid carriers through surface modification strategies ADMET & DMPK · 2024
    21. Safety of dermatologic medications in pregnancy and lactation Journal of The American Academy of Dermatology · 2014 · 73 citations
    22. Advanced nanocarrier- and microneedle-based transdermal drug delivery strategies for skin diseases treatment Theranostics · 2022 · 67 citations
    23. What do we know about phytotherapy of benign prostatic hyperplasia? Life Sciences · 2015 · 67 citations
    24. Sulfatase inhibitors: a patent review Expert Opinion on Therapeutic Patents · 2012 · 47 citations
    25. Therapeutic Applications of Nanoemulsion Based Drug Delivery Systems: A Review of Patents in Last Two Decades Recent Patents on Drug Delivery & Formulation · 2011 · 39 citations
    26. Consensus on the use of oral isotretinoin in dermatology - Brazilian Society of Dermatology Anais Brasileiros de Dermatologia · 2020 · 22 citations
    27. Trends in the Development of New Drugs for Treatment of Benign Prostatic Hyperplasia Current Medicinal Chemistry · 2006 · 14 citations
    28. New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats AAPS PharmSciTech · 2024 · 7 citations
    29. Hair Follicle Targeting with Nanoparticles Springer eBooks · 2012 · 5 citations
    30. A Comprehensive Review on Current and Future Trends of Nanoemulsions in Modern Cosmetics and Pharmaceuticals International Journal of Advanced Science and Engineering · 2025 · 2 citations