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    Glossary Lineage Tracing

    scientific method tracking cell development and differentiation over time

    Lineage tracing is a scientific technique used to track the development and fate of specific cells over time. By marking a group of cells with a unique identifier, researchers can observe how these cells divide, differentiate, and contribute to the formation of tissues and organs. This method is particularly useful in understanding how stem cells function and how diseases like cancer progress.

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    1. Theory and Practice of Lineage Tracing Stem Cells · 2015 · 69 citations
    2. Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts Methods in molecular biology · 2013 · 11 citations
    3. Genetic lineage tracing in skin reveals predominant expression of HEY2 in dermal papilla during telogen and that HEY2<sup>+</sup> cells contribute to the regeneration of dermal cells during wound healing Experimental Dermatology · 2023 · 2 citations
    4. Genetic Tools for Cell Lineage Tracing and Profiling Developmental Trajectories in the Skin Journal of Investigative Dermatology · 2024 · 6 citations
    5. Discovering New Progenitor Cell Populations through Lineage Tracing and In Vivo Imaging Cold Spring Harbor Perspectives in Biology · 2020 · 13 citations
    6. Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices Cell · 2017 · 214 citations
    7. Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair Frontiers in Cell and Developmental Biology · 2021 · 37 citations
    8. Stem cell identification-<i>in vivo</i> lineage analysis versus <i>in vitro</i> isolation and clonal expansion The Journal of Pathology · 2012 · 17 citations
    9. Tracing the cellular origin of cancer Nature Cell Biology · 2013 · 232 citations
    10. Tracing the developmental origin of tissue stem cells Development Growth & Differentiation · 2022 · 7 citations
    11. Distinct stem cells contribute to mammary gland development and maintenance Nature · 2011 · 721 citations
    12. Dedifferentiation of committed epithelial cells into stem cells in vivo Nature · 2013 · 551 citations
    13. Stem Cells and the Niche: A Dynamic Duo Cell Stem Cell · 2010 · 333 citations
    14. The Role of Stromal Stem Cells in Tissue Regeneration and Wound Repair Science · 2009 · 295 citations
    15. Diverse mechanisms for endogenous regeneration and repair in mammalian organs Nature · 2018 · 172 citations
    16. Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell? Cell Stem Cell · 2007 · 153 citations
    17. A matter of life and death: self‐renewal in stem cells EMBO Reports · 2012 · 150 citations
    18. Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments Nature Reviews Molecular Cell Biology · 2015 · 137 citations
    19. Fibroblast state switching orchestrates dermal maturation and wound healing Molecular Systems Biology · 2018 · 126 citations
    20. Compartmentalized organization: a common and required feature of stem cell niches? Development · 2010 · 63 citations
    21. BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions Stem cell reports · 2014 · 50 citations
    22. Defining Skin Fibroblastic Cell Types Beyond CD90 Frontiers in Cell and Developmental Biology · 2018 · 31 citations
    23. The Hair Follicle Bulge: A Niche for Adult Stem Cells Microscopy and Microanalysis · 2011 · 19 citations
    24. Thy1 marks a distinct population of slow-cycling stem cells in the mouse epidermis Nature communications · 2022 · 7 citations
    25. Fibroblast Heterogeneity in Healthy and Wounded Skin Cold Spring Harbor Perspectives in Biology · 2022 · 4 citations
    26. There and Back Again: Hair Follicle Stem Cell Dynamics Cell stem cell · 2011 · 4 citations
    27. MmuPV1-Induced Cutaneous Squamous Cell Carcinoma Arises Preferentially from Lgr5+ Epithelial Progenitor Cells Viruses · 2022 · 2 citations
    28. Reporting Live from the Epidermal Stem Cell Compartment! Cell Stem Cell · 2012 · 2 citations
    29. Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis JCI Insight · 2025 · 1 citations
    30. Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis 2021 · 1 citations