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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

Hair follicle regeneration possible, more research needed.

Higher leptin and lower vitamin D levels may contribute to male pattern baldness.

Higher BMI and lower testosterone are linked to more aggressive prostate cancer.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

Hormone treatment for transsexual individuals is effective but carries risks like thromboembolic events and mood changes, with most side effects being minor and reversible.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Hormones control reproduction and are crucial for body balance.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

A male with aromatase deficiency improved bone health with estradiol treatment.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Adults with certain skin conditions may have higher levels of inflammation in their body.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.