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In 1981, the punch graft technique was the main method for hair transplantation, and medical treatments for baldness were not very effective.

The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Natural products in cosmetics are beneficial for skin and hair care with low toxicity.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Niosomes improve minoxidil skin delivery for hair loss treatment.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Patients need long-term care after bariatric surgery to manage potential nutritional and metabolic issues.

Hair growth and pigmentation in mice involve specific stages crucial for research.

The method can effectively extract biomedical information without needing expert annotation, performing better than previous models.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Laser device increases hair density, safe for treating hair loss in men and women.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

RNAi-based biopesticides could be safe and effective for pest control with careful development and risk assessment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.