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    Glossary Laminin-332

    protein crucial for skin's structural integrity and function

    Laminin-332, also known as Laminin-5, is a protein crucial for the structural integrity and function of the skin. It is a key component of the basement membrane, which supports the attachment of the epidermis (outer skin layer) to the dermis (inner skin layer). Deficiencies or mutations in Laminin-332 can lead to skin disorders such as junctional epidermolysis bullosa, a condition characterized by fragile skin that blisters easily.

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    Research 30 of 768

    1. Laminin-511, inducer of hair growth, is down-regulated and its suppressor in hair growth, laminin-332 up-regulated in chemotherapy-induced alopecia Journal of dermatological science · 2010 · 13 citations
    2. Laminin 332 Is Indispensable for Homeostatic Epidermal Differentiation Programs 2021 · 12 citations
    3. Spatial and temporal control of laminin-511 and -332 expressions during catagen Journal of Dermatological Science · 2010 · 6 citations
    4. So Much More Than Just Structural Support: Laminin‐332 and Its Multifaceted Functions in Skin Homeostasis and Disease Experimental Dermatology · 2026
    5. Re-investigating the Basement Membrane Zone of Psoriatic Epidermal Lesions: Is Laminin-511 a New Player in Psoriasis Pathogenesis? 2018 · 13 citations
    6. A case of antilaminin 332 mucous membrane pemphigoid showing a blister on the bulbar conjunctiva and a unique epitope on the α3 subunit British Journal of Dermatology · 2010 · 7 citations
    7. Micropatterned dermal–epidermal regeneration matrices create functional niches that enhance epidermal morphogenesis Acta Biomaterialia · 2013 · 65 citations
    8. Dedicator of Cytokinesis 5 Regulates Keratinocyte Function and Promotes Diabetic Wound Healing Diabetes · 2021 · 25 citations
    9. Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids Stem cell reports · 2022 · 14 citations
    10. A missense mutation in Lama3 causes androgen alopecia Scientific Reports · 2023
    11. Functional analysis of collagen XVII in epithelial cancers and a mouse model DOAJ (DOAJ: Directory of Open Access Journals) · 2016
    12. Hair follicle markers, expression and modulation: Studies on human scalp skin grafts Journal of the American Academy of Dermatology · 2010
    13. Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis Genes & Development · 2008 · 102 citations
    14. A umbilical cord blood-derived exosome product simulates hair growth through laminin V and collagen XVII: an ex vivo study Archives of Dermatological Research · 2025
    15. Sıçan Derisinde Vimentin, Desmin ve Laminin’in Dağılımı Doğu Fen Bilimleri Dergisi · 2025
    16. Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis Matrix Biology · 2016 · 19 citations
    17. 438 Laminin-511 is a new player in the development of psoriasis and controlled via cannabinoid receptor type 1 2016
    18. Laminin α5 in the keratinocyte basement membrane is required for epidermal–dermal intercommunication Matrix Biology · 2016 · 57 citations
    19. Dual role of laminin‑511 in regulating melanocyte migration and differentiation Matrix Biology · 2018 · 17 citations
    20. Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration Chinese Medicine · 2023 · 1 citations
    21. Pro-Insulin-Like Growth Factor-II Ameliorates Age-Related Inefficient Regenerative Response by Orchestrating Self-Reinforcement Mechanism of Muscle Regeneration Stem Cells · 2015 · 19 citations
    22. Clinical and molecular features in a cohort of Middle Eastern patients with epidermolysis bullosa Pediatric dermatology · 2023
    23. Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men Cell Stem Cell · 2020 · 139 citations
    24. Alopecia in Epidermolysis Bullosa Dermatologic Clinics · 2009 · 21 citations
    25. Hair Loss in Autoimmune Cutaneous Bullous Disorders Dermatologic Clinics · 2011 · 12 citations
    26. Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro Experimental Cell Research · 2015 · 24 citations
    27. Systemic lupus erythematosus presenting with bullous lesions, cutaneous vasculitis and laryngeal ulcerations-a rare association International journal of research in dermatology · 2022
    28. Pathogenesis and clinical features of alopecia in epidermolysis bullosa: A systematic review Pediatric Dermatology · 2019
    29. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    30. 331 An open label clinical trial of the JAK inhibitor tofacitinib for alopecia areata Journal of Investigative Dermatology · 2017 · 2 citations