196 citations
,
March 2016 in “Nature Communications” In this study, researchers identified 18 genetic associations with scalp and facial hair traits in Latin Americans, including novel loci for hair greying and balding, with implications for understanding hair evolution.
2 citations
,
June 2018 in “International Journal of Pharmacological Research” This article reviews treatments for progeria, including aspirin, hydrotherapy, and farnesyl transferase inhibitors, but reports no new clinical results.
May 2009 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, a transgenic mouse model suggested that suppressing the expression of the HGPS mutation may reverse disease symptoms, including skin abnormalities, supporting the potential for treatment development.
January 2018 in “Stem cell biology and regenerative medicine” This review discusses how the nuclear lamina integrates biochemical and mechanical signals to influence gene expression and skin homeostasis, but reports no new clinical results.
29 citations
,
December 1998 in “Seminars in Cutaneous Medicine and Surgery” This review examines recent approvals and emerging treatments for androgenetic alopecia, discussing newly approved drugs like Propecia and Rogaine Extra Strength 5%, but without presenting new clinical results.
22 citations
,
October 1996 in “Dermatologic clinics” This review summarizes recent advances in understanding intermediate filament structure and their implications for pathological mutations and human diseases, but it reports no new experimental results.
November 2024 in “Journal of Investigative Dermatology” Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
45 citations
,
May 2003 in “Journal of Cell Science” This study found that α3β1-integrin is crucial for maintaining normal hair follicle morphology in mice, as its deficiency leads to severe abnormalities despite not affecting interfollicular epidermal differentiation.
13 citations
,
June 2018 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” This study found that the expression of laminin-511 and -332 was significantly increased in psoriasis skin lesions and may influence keratinocyte proliferation and apoptosis, suggesting a previously overlooked role in the disease's pathogenesis.
November 2024 in “Journal of Investigative Dermatology” Minoxidil rejuvenates hair follicles and reduces aging signs in male pattern baldness.
14 citations
,
September 2015 in “Ophthalmic plastic and reconstructive surgery” This case report concludes that the presence of distinctive histiocytic responses in a Cambodian woman's eyelid lipogranulomas suggests surreptitious silicone injections despite her denial of prior procedures.
1 citations
,
July 1973 in “British Journal of Dermatology” The document concludes that secondary syphilis cases are increasing and often misdiagnosed, pityriasis rubra pilaris can be distinguished from psoriasis by skin cell features, and different skin layers produce specific components during skin repair.
19 citations
,
November 1985 in “Archives of Dermatology” This case study documented a black male newborn developing large bullae that healed with hypopigmentation, suspecting proteolytic enzymes in keratinocytes caused the collagenolysis responsible for the condition.
October 2022 in “Hair Transplantation” This article discusses key considerations for hair loss treatment and restoration in Latin-American patients, emphasizing cultural and physical differences, but it reports no new clinical results.
October 2023 in “Revista Medicina Cutánea Ibero-Latino-Americana” In a study conducted on 257 Latin American patients with alopecia areata, researchers found that the most frequent lesion location was the scalp, affecting 86.1% of participants, and reported multiple associated comorbidities, notably cardiovascular and endocrine diseases, with certain conditions being more common in women.
9 citations
,
October 2014 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that acanthosis nigricans is highly prevalent in Latin American youths, especially at the knuckles, and may indicate early insulin resistance even in those with a normal BMI.
42 citations
,
September 2002 in “The Journal of Comparative Neurology” This study found that in the dorsal horn's lamina III, most afferent boutons form synapses with presynaptic boutons immunoreactive for GABA and/or glycine, influencing sensory pathways.
5 citations
,
March 2017 in “Journal of Dermatology” This survey reported that 37.6% of male AGA patients were satisfied with their treatments, with the highest satisfaction for 5-alpha-reductase inhibitors, and revealed differing perceptions between physicians and patients about AGA's impact on confidence and treatment involvement.
16 citations
,
May 2013 in “Urology” The authors concluded that components of metabolic syndrome were strongly associated with severe lower urinary tract symptoms in Latin American men, while alopecia was not an independent predictor.
4 citations
,
May 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that in Alcorcón, Spain, migrants from Sub-Saharan Africa, the Caribbean, and Latin-America had a higher risk of COVID-19 infection during the first wave compared to Spaniards.
36 citations
,
July 2020 in “American Journal of Infection Control” This study observed that males aged 60 to 79 were admitted and died from COVID-19 more frequently than females, and Latin Americans were more often admitted to the ICU.
December 2023 in “International Journal of Dermatology” This study observed that among transgender adults undergoing hormone therapy, common skin issues were acne, androgenetic alopecia, and other conditions, highlighting the need for dermatologists in their care; this is noted as the first Colombian and Latin American study on this topic.
9 citations
,
July 2010 in “British Journal of Dermatology” This article reports on lentiginosis observed within plaques of linear atrophoderma of Moulin and discusses its potential classification as a twin-spotting phenomenon but provides no new clinical research results.
2 citations
,
August 2004 in “Veterinary Dermatology” This case study in an 8-month-old mixed-breed dog with symptoms and histopathological findings supports a diagnosis of hereditary junctional epidermolysis bullosa, although specific genetic mutations weren't identified.
64 citations
,
November 2012 in “EMBO reports” This review discusses the role of lamins in development, tissue maintenance, and stress response, and does not report new experimental findings.
This article reviews current understanding of Hutchinson–Gilford Progeria Syndrome and suggests RNA-based treatments show promise, but no new clinical findings are reported.
340 citations
,
September 2014 in “PLOS Genetics” This study found that while genetic ancestry affects physical appearance traits in Latin American populations, it accounts for only a modest portion of the observed variation.
2 citations
,
November 2018 in “Medunab” This study found that in Colombian women with non-scarring alopecia, decreased serum ferritin levels were associated with telogen effluvium, but no such link was observed with thyroid disorders.
23 citations
,
December 2023 in “Skin Health and Disease” This study highlights a scarcity of data and treatment guidelines for vitiligo in Africa, the Middle East, and Latin America, emphasizing the need for regional epidemiological studies and tailored management approaches.
1 citations
,
January 2013 in “Lung India” This letter discusses how differentiating features in clinical and radiological findings can help distinguish pulmonary Langerhans cell histiocytosis and Birt-Hogg-Dube syndrome from lymphangioleiomyomatosis, noting overlapping symptoms but specific distinctive traits.