January 2020 in “Current trends in diagnosis & treatment” The review suggests doctors should carefully weigh risks and benefits of off-label drug use, involve patients in decisions, and calls for better regulations and monitoring.
September 2019 in “IP Indian journal of clinical and experimental dermatology” Hormones and iron deficiency are linked to female pattern hair loss, and hair thinning patterns are similar across different types of this condition.
January 2018 in “Journal of The American Academy of Dermatology” A manual blood cell counter was effectively used to count hair follicles during surgery, being user-friendly and cost-effective but limited by a three-digit display.
Off-label drug use can be risky but sometimes beneficial when standard treatments fail.
July 2022 in “Dermatologica Sinica” Many women with hair loss also have zinc deficiency, iron depletion, or thyroid issues.
130 citations,
February 2018 in “Journal of Investigative Dermatology” Tofacitinib may help treat severe hair loss, but more research is needed.
116 citations,
April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
45 citations,
February 2012 Obese women with PCOS are more likely to have fatty liver disease.
38 citations,
May 2006 in “Archives of Gynecology and Obstetrics” Women with only irregular periods or excess hair have a better hormone profile than those with full PCOS, but both groups are similar, indicating a need for better PCOS diagnosis methods.
28 citations,
January 2000 in “Medical Mycology” Fungal infections in lab animals can interfere with research.
27 citations,
April 2011 in “International journal of legal medicine” In situ DNA labeling in hair can help predict forensic DNA analysis success.
22 citations,
July 2016 in “Cellular and Molecular Life Sciences” Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
21 citations,
September 2013 in “Journal of circadian rhythms” Intense exercise at night can delay the body's internal clock gene expression by 2 to 4 hours.
21 citations,
January 2017 in “Skin Pharmacology and Physiology” Caffeine-based liquid 0.2% is as effective as minoxidil 5% for treating male hair loss.
16 citations,
May 2019 in “International Journal of Women's Dermatology” The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.
15 citations,
October 2016 in “Steroids” Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
9 citations,
November 2015 in “Gynecological Endocrinology” Different types of PCOS in Chinese Han women show varying levels of male hormone and metabolic issues.
9 citations,
September 2010 in “Dermatologic therapy” Combining cetirizine and topical steroids can effectively manage severe lichen planus pilaris.
8 citations,
December 2021 in “BMJ neurology open” Sodium selenate was found to be safe and possibly slows Alzheimer's progression, but more research is needed.
6 citations,
October 2020 in “medRxiv (Cold Spring Harbor Laboratory)” Early treatment improved COVID-19 outcomes, and spironolactone helped reduce risks in females with high androgen levels.
5 citations,
January 2019 in “Clinical Drug Investigation” Some off-label treatments increase hair density, but long-term safety unknown.
3 citations,
January 2019 in “Elsevier eBooks” Pharmacists should interpret lab data and perform physical exams to improve patient care.
3 citations,
March 2020 in “International Journal of Dermatology” Tildrakizumab showed limited effectiveness in treating chronic alopecia areata in a small group of patients.
3 citations,
February 2019 in “International Journal of Community Medicine and Public Health” Most off-label drug prescriptions in Saudi Arabia are for adults with depression and diabetes.
3 citations,
January 2019 in “Annals of medical research” The conclusion cannot be provided because the document content is not available.
3 citations,
April 2016 in “Journal of Investigative Dermatology” Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
2 citations,
December 2017 in “Journal of The American Academy of Dermatology” The article suggests that five common skin-related lab tests may be unnecessary and could cause extra cost and anxiety without improving patient care.
2 citations,
September 1980 in “Experientia” Polyethylene alanine caused hair loss in young lab animals but not in adults, with hair regrowth occurring within 20 days.
Vitamin supplements may not improve hair thickness or density in patients with non-scarring hair loss.