41 citations,
April 2019 in “PLOS genetics” CD34+ and CD34- melanocyte stem cells have different regenerative abilities.
36 citations,
November 2019 in “Molecular biology and evolution” Cysteine-rich keratins evolved independently in mammals, reptiles, and birds for hard skin structures like hair, claws, and feathers.
5 citations,
March 2019 in “Experimental dermatology” Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
21 citations,
May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
144 citations,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
2 citations,
December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
44 citations,
November 2011 in “The Journal of Dermatology” New understanding of the causes of primary cicatricial alopecia has led to better diagnosis and potential new treatments.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
47 citations,
January 2015 in “Dermatology” The best way to treat acne is to prevent healthy skin glands from turning into acne lesions by controlling the triggers early on.
27 citations,
November 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
2 citations,
May 2023 in “Cancer medicine” KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.
31 citations,
April 2019 in “Cell reports” Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
211 citations,
April 2018 in “Cold Spring Harbor Perspectives in Biology” Keratins are crucial for cell structure, growth, and disease risk.
September 2023 in “Nature communications” Alk1 in specific cells is crucial for proper nerve branching and hair function.
January 2023 in “Czech Journal of Animal Science” Proteins influence the quality and traits of cashmere goat fleece, affecting hair strength and diameter.
1 citations,
August 2023 in “Journal of cutaneous pathology” The analysis of a large pilomatricoma revealed five distinct areas with different gene activity related to hair growth and tumor development.
38 citations,
June 2017 in “The Journal of Dermatology” Aging in hair follicle stem cells leads to hair graying, thinning, and loss.
199 citations,
April 2010 in “Nature” A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.
5 citations,
October 2014 in “Methods” The document explains how to create detailed biological pathways using genomic data and tools, with examples of hair and breast development.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
1 citations,
July 2023 in “Nature communications” MOF controls key genes for skin development by regulating mitochondrial and ciliary functions.
129 citations,
July 2019 in “Stem Cell Research & Therapy” Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
21 citations,
January 2018 in “Journal of Investigative Dermatology” Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.
September 2023 in “Stem Cells International” Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.
82 citations,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
28 citations,
March 2016 in “Toxicologic pathology” Dogs could be good models for studying human hair growth and hair loss.
10 citations,
December 2021 in “Frontiers in cell and developmental biology” The research identified genes that explain why some sheep have curly wool and others have straight wool.
15 citations,
July 2017 in “PubMed” Injecting a mix of human skin and hair cells into mice can grow new hair.