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Research 30 of 44
- KRASG12D mutant cells are outcompeted by wild type neighbours in adult pancreas in an EPHA2-dependent manner
- YAP and TAZ are essential for basal and squamous cell carcinoma initiation
- Stem cell quiescence acts as a tumour suppressor in squamous tumours
- Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling
- Tumor suppressor identity can contribute to heterogeneity of phenotype in hair follicle stem cell‐induced squamous cell carcinoma
- LB1011 Oncogenic ras mutation induces spatiotemporally specific tissue deformation through converting fluctuated into sustained ERK activation
- Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation
- Injury suppresses Ras cell competitive advantage through enhanced wild-type cell proliferation
- Drug Repurposing against KRAS Mutant G12C: A Machine Learning, Molecular Docking, and Molecular Dynamics Study
- Tracing the cellular origin of cancer
- Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
- Roles of tumor suppressors in regulating tumor-associated inflammation
- Oncogenic senescence: a multi-functional perspective
- <i>Pten</i> loss in Lgr5<sup>+</sup> hair follicle stem cells promotes SCC development
- Clonal analysis of stem cells in differentiation and disease
- Development and homeostasis of the sebaceous gland
- New insights into the functions of Cox-2 in skin and esophageal malignancies
- Benefit-Risk Assessment of GLP-1 Receptor Agonists: Implications for Dermatologists and Plastic Surgeons
- Proteolysis‐Targeting Chimera (PROTAC): Current Applications and Future Directions
- First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors
- Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition
- Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions
- Leveraging nature’s nanocarriers: Translating insights from extracellular vesicles to biomimetic synthetic vesicles for biomedical applications
- Increased lactate dehydrogenase activity is dispensable in squamous carcinoma cells of origin
- The Aldo-Keto Reductase AKR1B10 Is Up-Regulated in Keloid Epidermis, Implicating Retinoic Acid Pathway Dysregulation in the Pathogenesis of Keloid Disease
- Pleiotropic Role of Notch Signaling in Human Skin Diseases
- Somatic Mutations in Normal Tissues: New Perspectives on Early Carcinogenesis
- The Glypican-1/HGF/C-Met and Glypican-1/VEGF/VEGFR2 Ternary Complexes Regulate Hair Follicle Angiogenesis
- Targeting the Hippo/YAP/TAZ signalling pathway: Novel opportunities for therapeutic interventions into skin cancers
- Volume imaging to interrogate cancer cell-tumor microenvironment interactions in space and time