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In this case series, low-dose oral metformin was associated with improvements in symptoms and gene expression changes in Black female patients with treatment-resistant central centrifugal cicatricial alopecia, suggesting a potential therapeutic role for metformin in managing this condition.

This study found that patients with alopecia areata have distinct mRNA and lncRNA expression profiles between normal and bald scalp areas, identifying differentially expressed genes and revealing potential biomarkers for diagnosis, with keratin family genes possibly playing a key role in the disease's pathogenesis.

This report describes the diagnosis and treatment of traumatic anserine folliculosis in children, highlighting its distinct skin features and suggesting tretinoin cream as an effective remedy.

CD8+ T cells attack hair follicle stem cells, causing scarring and hair loss in Discoid Lupus.

In this study, researchers observed that spontaneously mutated mice with a hair loss phenotype exhibited significant differential expression of genes related to keratinization and hair follicle formation, suggesting these mice could model human alopecia for future research and treatment development.

This study established an animal model using UV-irradiated C57BL/6 mice to assess hair luster, reporting that UV exposure alters keratin-associated protein gene expression, and suggested potential for developing effective hair care products by evaluating treatments like oral minoxidil.

This biographical abstract highlights George Rogers' pioneering contributions to the understanding of keratin molecular structure and keratinisation biochemistry, including the application of electron microscopy to hair ultrastructure and the discovery of enzymes and gene transcription processes relevant to keratin proteins.

This study identified core genes and pathways involved in androgenetic alopecia, finding that genes related to hair follicle development are down-regulated, while those linked to immune responses are up-regulated, highlighting potential therapeutic targets.

Loose anagen hair syndrome causes easily shed hair but usually improves with time.

This case report described a facial hairline tumor initially diagnosed as a sebaceous cyst but ultimately confirmed as a rare Proliferating Pilar Tumor with focal malignancies upon histopathological examination.

This study concluded that combination therapies often yield better results for treating atrophic post-acne scars than single treatments.

This study found differential expression of genes related to hair fiber production in Pashmina and Barbari goats, potentially enhancing pashmina fiber quality and informing future enrichment analyses.

This review discusses loose anagen hair syndrome in children, characterized by non-scarring alopecia and increased hair shedding, and reports no new results; topical minoxidil may be used as a treatment.

This research suggests that mouse mutants and genomics can help study hair biology and epithelial differentiation by focusing on the role of the Foxn1 gene.

This study identified a specific genetic variant in the CCHCR1 gene that may contribute to alopecia areata through impaired keratinization, suggesting an alternative mechanism beyond autoimmune causes.

This chapter reviews various fungal skin diseases affecting cattle but does not report new research findings; it focuses on rare, inherited, and congenital conditions like follicular dysplasia and cutaneous asthenia.

This chapter reviews fungal skin diseases in goats and their hereditary aspects, but it does not present new experimental results.

In this study, treatments using a shampoo and conditioner with hematin helped repair damaged hair by depositing a cuticle-like structure, straightening hair as observed through electron microscopy.

This source provides a comprehensive review of acne vulgaris, highlighting its pathophysiology, epidemiology, molecular mechanisms, and treatment options, emphasizing the significance of addressing acne's psychosocial burden for adolescents and beyond.

This study observed that hair follicle cuticular cells undergoing keratinization were significantly thicker than those in a normal hair shaft, due to incomplete loss of cytosol.

This article lists online educational resources from the American Society of Plastic Surgeons but reports no new research findings.

Ichthyoses are skin disorders causing scales, with treatment depending on type and severity.

This study found that ingesting seeds from the Lecythis ollaria tree may cause hair loss and other toxic effects in animals.

This study found that scalp treatments improved hair density and reduced the number of telogen bulbs in patients with Telogen Effluvium.

This review discusses loose anagen hair syndrome, a benign and self-limited condition predominantly affecting children, and highlights the importance of differentiating it from other hair disorders like telogen effluvium and trichotillomania, but reports no new results.

This report describes an unusual case of proliferating trichilemmal cyst with trichoepitheliomatous change in a young woman, differing from its typical presentation in elderly women.

This study found a significantly higher density of Demodex mites in sebaceous hyperplasia lesions compared to controls, suggesting a possible link between Demodex and the development of these skin lesions.

This review discusses the cell biological characteristics of the outer root sheath of normal human hair follicles and highlights some similarities and differences with trichilemmal tumors, but reports no new results.

This study found that skin sulfhydryl oxidase plays a role in keratinization and may contribute to skin's protective functions, with its expression influenced by irritants and differentiation modifiers.

This study suggests that human hair follicle cells and epidermal keratinocytes differ in their degree of keratinization and other characteristics when cultured on mixed collagen membranes.