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    Glossary Keratin-Associated Proteins

    bind to keratin fibers, strengthening hair and nails

    Keratin-Associated Proteins (KAPs) are a group of proteins that bind to keratin fibers, which are the structural components of hair, nails, and the outer layer of skin. They play a crucial role in the formation and strength of these keratin structures by cross-linking with keratin, thereby enhancing the rigidity and resilience of hair and other keratinized tissues.

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    1. Variation in the ovine keratin-associated protein 15-1 gene affects wool yield The Journal of Agricultural Science · 2018 · 18 citations
    2. Characterization of Human KAP24.1, A Cuticular Hair Keratin-Associated Protein with Unusual Amino-Acid Composition and Repeat Structure 2007 · 51 citations
    3. Exploring the effects of wetting and free fatty acid deposition on an atomistic hair fiber surface model incorporating Keratin Associated Protein 5-1 2022
    4. Variation in the caprine keratin-associated protein 15-1 (KAP15-1) gene affects cashmere fibre diameter 2019 · 30 citations
    5. Identification of the Ovine Keratin-Associated Protein 21-1 Gene and Its Association with Variation in Wool Traits Animals · 2019 · 7 citations
    6. Polymorphisms in the Human High Sulfur Hair Keratin-associated Protein 1, KAP1, Gene Family 2002 · 48 citations
    7. Characterization of the Promoter Regions of Two Sheep Keratin-Associated Protein Genes for Hair Cortex-Specific Expression PloS one · 2016 · 14 citations
    8. Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine Genes · 2019 · 24 citations
    9. Protein extraction from human anagen head hairs 1-millimeter or less in total length 2018 · 18 citations
    10. Isolation and Characterization of a Novel Hair Follicle–Specific Gene, Hacl-1 Journal of Investigative Dermatology · 1994 · 25 citations
    11. The Mechanisms of Fur Development and Color Formation in American Mink Revealed Using Comparative Transcriptomics Animals · 2022 · 1 citations
    12. Isolation and Characterization of a Putative Keratin-Associated Protein Gene Expressed in Embryonic Skin of Mice Journal of Investigative Dermatology · 1998 · 22 citations
    13. Revealing biological mechanisms of skin pigment recovery during treatment in vitiligo patients: A proteomic analysis Journal of Investigative Dermatology · 2026
    14. Mammalian keratin associated proteins (KRTAPs) subgenomes: disentangling hair diversity and adaptation to terrestrial and aquatic environments BMC genomics · 2014 · 65 citations
    15. Effects of FGF5-mediated LncRNA on the skin fibroblast growth of Liaoning Cashmere goats Indian Journal of Animal Health · 2023
    16. An Investigation of Hair and its Keratin Associated Proteins using Advanced Light Microscopy Durham e-Theses (Durham University) · 2019
    17. Proteomic analysis of hair shaft and nail plate. PubMed · 2011 · 29 citations
    18. Bioinformatics analysis of EST segment from goat China Journal of Bioinformatics · 2008 · 1 citations
    19. Characterisation of the Ovine KRTAP36-1 Gene in Chinese Tan Lambs and Its Impact on Selected Wool Traits Animals · 2025
    20. Transglutaminase-3 Enzyme: A Putative Actor in Human Hair Shaft Scaffolding? 2008 · 30 citations
    21. Identification of the keratin-associated protein 13-3 (KAP13-3) gene in sheep Open Journal of Genetics · 2011 · 26 citations
    22. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1 2002 · 100 citations
    23. Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11 Biochemical and Biophysical Research Communications · 2004 · 27 citations
    24. Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11*1 Biochemical and Biophysical Research Communications · 2004 · 1 citations
    25. Krtap16, Characterization of a New Hair Keratin-associated Protein (KAP) Gene Complex on Mouse Chromosome 16 and Evidence for Regulation by Hoxc13 Journal of Biological Chemistry · 2004 · 47 citations
    26. Krtap11-1, a hair keratin-associated protein, as a possible crucial element for the physical properties of hair shafts Journal of Dermatological Science · 2014 · 38 citations
    27. Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales Scientific reports · 2022 · 5 citations
    28. Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion 2011 · 30 citations
    29. Identification of the Ovine Keratin-Associated Protein 26-1 Gene and Its Association with Variation in Wool Traits Genes · 2017 · 29 citations
    30. Identification of skin-expressed genes possibly associated with wool growth regulation of Aohan fine wool sheep BMC Genetics · 2014 · 30 citations