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    Glossary Keratin-Associated Proteins

    bind to keratin fibers, strengthening hair and nails

    Keratin-Associated Proteins (KAPs) are a group of proteins that bind to keratin fibers, which are the structural components of hair, nails, and the outer layer of skin. They play a crucial role in the formation and strength of these keratin structures by cross-linking with keratin, thereby enhancing the rigidity and resilience of hair and other keratinized tissues.

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    1. Characterization of the Human Hair Shaft Cuticle–Specific Keratin-Associated Protein 10 Family Journal of Investigative Dermatology · 2013 · 11 citations
    2. Polymorphisms in the Human High Sulfur Hair Keratin-associated Protein 1, KAP1, Gene Family 2002 · 48 citations
    3. Variation in the caprine keratin-associated protein 15-1 (KAP15-1) gene affects cashmere fibre diameter 2019 · 30 citations
    4. Identification of the Ovine Keratin-Associated Protein 21-1 Gene and Its Association with Variation in Wool Traits Animals · 2019 · 7 citations
    5. Exploring the effects of wetting and free fatty acid deposition on an atomistic hair fiber surface model incorporating Keratin Associated Protein 5-1 2022
    6. Identification of the Ovine Keratin-Associated Protein 26-1 Gene and Its Association with Variation in Wool Traits Genes · 2017 · 29 citations
    7. Location of keratin-associated proteins in developing fiber cuticle cells using immunoelectron microscopy International journal of trichology · 2010 · 10 citations
    8. Characterisation of an Ovine Keratin Associated Protein (KAP) Gene, Which Would Produce a Protein Rich in Glycine and Tyrosine, but Lacking in Cysteine Genes · 2019 · 24 citations
    9. ATOMISTIC CHARACTERIZATION OF HEALTHY AND DAMAGED HAIR SURFACES: A MOLECULAR DYNAMICS STUDY OF FATTY ACIDS ON PROTEIN LAYER ChemBioChem · 2024
    10. A novel purification procedure for keratin-associated proteins and keratin from human hair Journal of Biological Macromolecules · 2013 · 54 citations
    11. The susceptibility of disulfide bonds to modification in keratin fibers undergoing tensile stress Biophysical Journal · 2022 · 11 citations
    12. Highly Conserved Keratin-Associated Protein 7-1 Gene in Yak, Taurine and Zebu Cattle Folia biologica · 2017 · 2 citations
    13. Peer Review #2 of "Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis (v0.1)" 2014
    14. Label-free proteomics to identify keratins and keratin-associated proteins and their effects on the fleece traits of Inner Mongolia Cashmere Goats Czech Journal of Animal Science · 2023
    15. Polymorphism of keratin-associated protein (KAP) 7 gene and its association with wool traits in Rambouillet sheep The Indian Journal of Animal Sciences · 2018 · 3 citations
    16. Molecular Cloning of 5′ Flanking Region of Ovine Keratin Associated Protein 6-1 Gene and Comparison of the Sequences Journal of Inner Mongolia University · 2007
    17. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair BMC Evolutionary Biology · 2008 · 119 citations
    18. Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle BMC ecology and evolution · 2023 · 2 citations
    19. Mammalian keratin associated proteins (KRTAPs) subgenomes: disentangling hair diversity and adaptation to terrestrial and aquatic environments BMC genomics · 2014 · 65 citations
    20. Diversity of Trichocyte Keratins and Keratin Associated Proteins Advances in experimental medicine and biology · 2018 · 16 citations
    21. Keratin-Associated Protein Nanoparticles as Hemostatic Agents ACS applied nano materials · 2021 · 11 citations
    22. Comparative genomics of the keratin-associated protein (KAP) gene clusters in human, chimpanzee, and baboon Mammalian genome · 2004 · 8 citations
    23. Exploring the Effects of Wetting and Free Fatty Acid Deposition on an Atomistic Hair Fiber Surface Model Incorporating Keratin-Associated Protein 5-1 Langmuir · 2023 · 1 citations
    24. The Mechanisms of Fur Development and Color Formation in American Mink Revealed Using Comparative Transcriptomics Animals · 2022 · 1 citations
    25. Correlation analysis of four KRTAP gene polymorphisms and cashmere fiber diameters in two cashmere goat breeds Canadian journal of animal science · 2022
    26. Molecular Evolution of The Keratin‐associated Protein Gene Family Encyclopedia of Life Sciences · 2009
    27. Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins Journal of Morphology · 2012 · 33 citations
    28. Wool fiber curvature is correlated with abundance of K38 and specific keratin‐associated proteins Proteins · 2021 · 3 citations
    29. Differential expression of keratin and keratin associated proteins are linked with hair loss condition in spontaneously mutated inbred mice bioRxiv (Cold Spring Harbor Laboratory) · 2024
    30. Keratin Gene Expression Differences in Wool Follicles and Sequence Diversity of High Glycine-Tyrosine Keratin-Associated Proteins (Kaps) in Magra Sheep of India Journal of Natural Fibers · 2018 · 9 citations