60 citations,
November 2013 in “Development” Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.
1 citations,
January 2023 in “Biochemical and biophysical research communications” Keratin 79 is linked to liver damage and may help diagnose liver diseases.
5 citations,
December 2020 in “Experimental dermatology” A specific type of skin cell creates an opening for hair to grow out, and problems with this process can lead to skin conditions.
April 2017 in “Journal of Investigative Dermatology” Early and late matrix progenitors in hair follicles create different cell layers, with early ones forming the companion layer and later ones forming the inner root sheath and hair shaft.
April 2017 in “Journal of Investigative Dermatology” Sweat glands and hair follicles are determined by opposing signals, with BMPs promoting sweat glands and blocking BMPs leading to hair follicles.
Collagen VI is crucial for nerve function and affects wound-induced hair regrowth.
November 2023 in “BMC genomics” The study concluded that the arachidonic acid pathway and the protein KRT79 play a role in determining the fineness of cashmere.
7 citations,
November 2022 in “Communications biology” Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
30 citations,
March 2017 in “ACS biomaterials science & engineering” Hair follicles are valuable for regenerative medicine and wound healing.
22 citations,
April 2020 in “Scientific reports” Changthangi goats have specific genes that help produce Pashmina wool.
17 citations,
October 2017 in “Scientific reports” Fine wool sheep have more genes for wool quality, while coarse wool sheep have more for skin and muscle traits.
4 citations,
January 2019 in “International journal of molecular sciences” Genetically modified sheep with more β-catenin grew more wool without changing the wool's length or thickness.
Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.
April 2017 in “Journal of Investigative Dermatology” Chemotherapy and radiation therapy cause skin and hair damage by altering gene expression and signaling pathways.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.
32 citations,
May 2015 in “Journal of Investigative Dermatology” Mice without collagen VI have slower hair growth normally but faster regrowth after injury.
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
47 citations,
September 2015 in “Cell Cycle” Different skin stem cells help heal wounds, with hair follicle cells becoming more important over time.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
48 citations,
May 2015 in “NPJ microgravity” A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.
38 citations,
September 2014 in “Cell and Tissue Research” The hair follicle infundibulum plays a key role in skin health and disease, and understanding it better could lead to new skin disease treatments.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
7 citations,
January 2021 in “Evidence-based complementary and alternative medicine” Porphyra-334 may help reduce wrinkles and promote hair growth.
1 citations,
April 2017 in “Journal of Investigative Dermatology” Higher minoxidil dose helps hair growth in non-responders without side effects.
April 2017 in “Journal of Investigative Dermatology” Researchers improved a method to study individual cells in newborn mouse skin and found a way to assess the severity of a skin condition in humans.
April 2017 in “Journal of Investigative Dermatology” The study found a link between the severity of Lichen Planopilaris seen by doctors and the details seen under a microscope, and created a new way to measure this severity.
22 citations,
July 2016 in “Cellular and Molecular Life Sciences” Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
143 citations,
May 2017 in “Nature cell biology” Wounded skin cells can revert to stem cells and help heal.
13 citations,
April 2018 in “Scientific Reports” The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.