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    Glossary Keratin 2

    protein providing structural strength to skin, hair, and nails

    Keratin 2 (KRT2) is a type of protein found in the outer layer of the skin, hair, and nails. It plays a crucial role in providing structural strength and resilience to these tissues, helping to protect them from damage and wear. Mutations in the KRT2 gene can lead to skin disorders such as ichthyosis bullosa of Siemens, which is characterized by blistering and scaling of the skin.

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    Research 30 of 1000+

    1. Binding Interactions of Keratin-Based Hair Fiber Extract to Gold, Keratin, and BMP-2 PloS one · 2015 · 22 citations
    2. The Mean Staple Length of Wool Fibre Is Associated with Variation in the Ovine Keratin-Associated Protein 21-2 Gene Genes · 2020 · 4 citations
    3. Identification of the Keratin-Associated Protein 22-2 Gene in the Capra hircus and Association of Its Variation with Cashmere Traits Animals · 2023 · 1 citations
    4. Histopathological Analysis on keratin2-6 g Expression in Hair Mutant Mouse Hague Proceedings of The Japanese Society of Animal Models for Human Diseases · 2002
    5. Ovine KRTAP36-2: A New Keratin-Associated Protein Gene Related to Variation in Wool Yield Genes · 2023
    6. Identification and sequence analysis of the keratin-associated protein 24‐1 (KAP24-1) gene homologue in sheep Gene · 2012 · 51 citations
    7. Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair (vol 8, pg 241, 2008) 2009
    8. Alkylation of human hair keratin for tunable hydrogel erosion and drug delivery in tissue engineering applications Acta biomaterialia · 2015 · 75 citations
    9. Ferulic Acid Induces Keratin 6α via Inhibition of Nuclear β-Catenin Accumulation and Activation of Nrf2 in Wound-Induced Inflammation Biomedicines · 2021 · 16 citations
    10. Type 2 Diabetic Mellitus Inhibits Skin Renewal through Inhibiting WNT-Dependent Lgr5+ Hair Follicle Stem Cell Activation in C57BL/6 Mice Journal of diabetes research · 2022 · 6 citations
    11. ERK1/2 Pathway Is Involved in the Enhancement of Fatty Acids from Phaeodactylum tricornutum Extract (PTE) on Hair Follicle Cell Proliferation BioMed Research International · 2020 · 2 citations
    12. The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles Open Life Sciences · 2023
    13. SkIndia Quiz 24: Itchy papules over face Indian Dermatology Online Journal · 2016
    14. Peer Review #2 of "Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis (v0.1)" 2014
    15. Identification of Telogen Markers Underscores that Telogen Is Far from a Quiescent Hair Cycle Phase 2011 · 21 citations
    16. Artificial Infestation of Sarcoptes scabiei (Acari: Sarcoptidae) in Rabbits Exhibits Progressive Pathological Changes, Apoptosis, and Keratinization in the Skin International journal of molecular sciences · 2023 · 1 citations
    17. Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats Frontiers in Veterinary Science · 2025
    18. Polyphenolization:Hair Browning by Phenolic Adhesion,Ambient Oxygen, and Transition Metals OPAL (Open@LaTrobe) (La Trobe University) · 2025
    19. 186 Dissecting the role of the common neurotrophin receptor CD271 in the skin: generation and characterization of a novel mouse model with keratinocyte-specific conditional deletion 2022
    20. Thyroid Hormones Directly Alter Human Hair Follicle Functions: Anagen Prolongation and Stimulation of Both Hair Matrix Keratinocyte Proliferation and Hair Pigmentation The Journal of Clinical Endocrinology & Metabolism · 2008 · 115 citations
    21. The Mechanisms of Fur Development and Color Formation in American Mink Revealed Using Comparative Transcriptomics Animals · 2022 · 1 citations
    22. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    23. Correction of Tear Trough Deformity Using Autologous Fibroblast Combined with Keratin: New Soft Tissue Filler Aesthetic plastic surgery · 2018 · 12 citations
    24. Chronological ageing of human hair keratin fibres International Journal of Cosmetic Science · 2010 · 49 citations
    25. Downregulation of mRNAs Encoding Keratin-Associated Proteins in the Tongue of Mice Fed a High-Fat Diet Journal of Hard Tissue Biology · 2024
    26. Multiomics Analysis of the Response to Ritlecitinib in Alopecia Areata Subtypes and Correlation With Efficacy Allergy · 2025
    27. Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1 2002 · 100 citations
    28. Immunohistochemical Expression of Keratins in Normal Ovine Skin and in Chronic Dermatitis due to Sarcoptes scabiei Journal of comparative pathology · 2021 · 2 citations
    29. Table 1_Molecular mechanisms underlying cashmere quality differences between Jiangnan cashmere goats and Changthangi pashmina goats.xlsx OPAL (Open@LaTrobe) (La Trobe University) · 2025
    30. Human hair keratin hydrogel : fabrication, characterization and application 2014