May 2024 in “Dermatologic therapy” AKN is a chronic scalp condition in African-descended males, treated with topicals, antibiotics, steroids, and sometimes surgery or laser.
July 2018 in “Elsevier eBooks” Acne keloidalis nuchae is a chronic skin condition more common in African men, causing itchy or painful bumps and can lead to permanent hair loss if not treated early.
The combination therapy effectively improved acne keloidalis nuchae.
June 2021 in “Journal of The American Academy of Dermatology” The "spade sign" is a highly specific indicator for diagnosing acne keloidalis.
April 2019 in “Journal of the Dermatology Nurses’ Association” A 37-year-old man with hair loss and skin issues was successfully treated with oral antibiotics, highlighting the need for early treatment. Long-term care includes low-dose antibiotics and avoiding caps and wigs.
May 2019 in “Journal of the Dermatology Nurses’ Association” Folliculitis decalvans mainly affects middle-aged African American men and is treated with antibiotics.
April 2024 in “International journal of molecular sciences” Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
305 citations,
March 2018 in “International journal of molecular sciences” The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.
63 citations,
September 1987 in “Journal of Biological Chemistry” Minoxidil slows fibroblast growth and collagen production, potentially treating keloids, hypertrophic scars, and connective tissue disorders.
18 citations,
April 1989 in “Clinics in Dermatology” The argon gas-based cryotherapy effectively reduced keloid scars but caused some hypopigmentation and had a recurrence rate, especially in Afro-American patients.
December 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” Glycerol may improve wound healing and prevent keloids, a device can measure itch intensity, male pattern baldness is highly heritable, and fumaric acid esters may work for psoriasis by causing cell death in T cells.
Wound healing involves three phases and various cells and factors, with scars typically forming in adults. Chronic wounds can occur due to various issues, and abnormal scarring can lead to hypertrophic or keloid scars. Emerging research areas include the role of proteins, microRNAs, macrophage manipulation, and stem cell treatment.
176 citations,
June 2019 in “Cells” Different fibroblasts play key roles in skin healing and scarring.
113 citations,
June 2019 in “F1000Research” Scarless healing is complex and influenced by genetics and environment, while better understanding could improve scar treatment.
105 citations,
April 2004 in “Dermatologic Therapy” The document concludes that proper diagnosis and a combination of medical, hair-care, and surgical treatments are important for managing alopecia in black women.
92 citations,
June 2017 in “Journal of Plastic Reconstructive and Aesthetic Surgery” Microneedling is a safe and effective treatment for various skin conditions, often preferred for its fewer side effects and shorter recovery time.
90 citations,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
81 citations,
January 2000 in “American journal of clinical dermatology” Various treatments can improve post-acne scars, but results vary.
65 citations,
March 2018 in “Journal of Dermatological Science” Skin problems can be caused or worsened by physical forces and pressure on the skin.
64 citations,
January 2004 in “American journal of clinical dermatology” Folliculitis is an inflammation of hair follicles that requires proper diagnosis and treatment based on the specific cause.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
48 citations,
August 1998 in “Journal of the American Academy of Dermatology” Retinoids help manage skin conditions in black individuals.
38 citations,
June 2005 in “Matrix Biology” Minoxidil affects collagen-related genes, potentially helping treat fibrosis.
35 citations,
October 2019 in “Journal of pediatric health care” Children with darker skin tones can have specific skin conditions that need tailored treatments.
35 citations,
October 2003 in “Dermatologic clinics” Laser therapy on darker skin has higher risks and needs expert handling.
34 citations,
September 2009 in “International Journal of Dermatology” Using anabolic-androgenic steroids can cause skin problems like acne and hair loss in athletes.
32 citations,
July 2017 in “Molecular diagnosis & therapy” MicroRNA-21 could help diagnose and treat skin fibrosis.
30 citations,
May 2014 in “American Journal of Clinical Dermatology” The conclusion is that better understanding and more research are needed to effectively manage follicular and scarring disorders in skin of color, with an emphasis on patient education and cultural awareness.
29 citations,
September 2012 in “Birth Defects Research” Wounds heal without scarring in early development but later result in scars, and studying Wnt signaling could help control scarring.
28 citations,
April 2023 in “Stem cell research & therapy” Tiny vesicles from stem cells could be a new treatment for healing wounds.