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This study found that keratin K1014chim expression in mice did not reduce epidermal cell proliferation but increased susceptibility to benign tumors, challenging previous beliefs about K10's role in inhibiting tumor development.

This study found that extracellular vesicles from mesenchymal and outer root sheath stem cells may inhibit hair follicle stem cell apoptosis, suggesting potential therapeutic benefits for hair loss treatments.

Estetrol may help prevent hair loss and support hair growth in women.

This study observed that treating hair follicles with BM15766 and 7DHC led to structural damage, disrupted cellular organization, reduced expression of key genes and proteins, and increased apoptosis, in contrast to controls, indicating detrimental effects on hair follicle integrity.

This study found that a novel choline-based valproic acid ionic liquid significantly enhances transdermal penetration and promotes hair regrowth without causing irritation or toxicity, offering a promising treatment option for alopecia.

In this study, a bleaching protocol was developed to evaluate hair repair products, revealing that K18® and Olaplex® improve hair brightness and lightness, with distinct impacts on hair fiber properties.

This study found that both marine and bovine collagen peptides may help prevent hair loss by supporting epithelial hair follicle stem cell functions, with marine peptides maintaining hair in the growth phase and bovine peptides increasing stem cell presence in hair follicle regions.

In this study, researchers found that AP-2α and AP-2β are critical for maintaining epidermal homeostasis in adult skin, with their combined loss leading to severe skin and hair abnormalities and early skin inflammation due to impaired keratinocyte differentiation.

This study suggests that linalool, a common allergen in personal care products, may contribute to frontal fibrosing alopecia pathogenesis by triggering immune responses and depleting hair follicle stem cells, especially in sensitized individuals.

This case report discusses a 15-year-old boy with pachyonychia congenita, identifying a keratin 17 gene mutation, and highlights the need for a national registry and more accessible genetic testing in India.

This study found that marine-derived collagen peptides slightly promoted hair matrix proliferation and prolonged hair growth phase in human hair follicles ex vivo, suggesting potential benefits for hair loss treatment.

This study suggests that allergens like linalool found in personal care products may contribute to the pathobiology of frontal fibrosing alopecia by affecting immune responses and stem cell function in hair follicles.

This study found that STRIP1 and the STRIPAK complex play a key role in regulating F-actin and cell-cell junctions, which are essential for maintaining the epidermal barrier in mouse skin.

Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.

This study suggests that bovine and fish-derived collagen peptides may help maintain or prolong the hair growth phase and balance hair follicle stem cell populations, potentially benefiting aging and hair loss conditions like androgenetic alopecia.

This study suggests that impaired Nrf2 signaling and its relationship with keratin 16 may contribute to follicular hyperkeratinization and occlusion in hidradenitis suppurativa, opening new therapeutic avenues.

This study found that the cosmetic olfactory receptor agonist cyclohexyl salicylate may stimulate hair growth and expand stem cell progeny, suggesting potential as a cosmetic adjuvant for hair loss.

This study revealed that nestin-expressing progenitor cells capable of becoming ORS keratinocytes are present during both hair follicle development and in adult hair follicles.

This study found that exosomes from human dermal papilla cell cultures, particularly in an oxygen-permeable 3D environment, most effectively supported hair follicle stem cell maintenance and promoted hair follicle formation in vitro.

This study found that CTCF is crucial for proper skin and hair follicle development in mice, affecting keratinocyte differentiation and gene expression in keratin loci.

This study found that fibrosis-associated trochanters in central centrifugal cicatricial alopecia are enriched with hair follicle stem cells and may indicate a disrupted stem cell niche contributing to scarring.

This study found that apple stem cell extract may selectively influence hair follicle bulge stem cell biology without cytotoxic effects in an ex vivo human hair follicle organ culture.

Targeting immune pathways like JAK/STAT may help treat frontal fibrosing alopecia.

This study found that the PPAR-γ modulator AGED can reverse epithelial-mesenchymal transition in hair follicles affected by lichen planopilaris ex vivo, suggesting potential for treating scarring alopecias.

This study found that lymphatic vessels promote hair follicle growth in mice, suggesting new therapeutic strategies for hair loss treatments.

This study found that full thickness wounds in Lanyu pigs led to altered molecular expression and abnormal skin structure, without regenerating key epithelial cells thought to aid in skin regeneration.

This study found that targeting mTORC1 with rapamycin effectively inhibited skin tumor promotion in a mouse model, highlighting a potential target for cancer chemoprevention.

This study found that rabbit hair follicle stem cells, combined with electro-spun nano silk fibers, successfully constructed a tissue-engineered urethra, suggesting potential for future in vivo repair studies.

This review discusses the evolving understanding of epithelial stem cells, noting how new models challenge old assumptions and suggesting multiple stem cell populations contribute differently to skin and hair follicle regeneration.

In this study, researchers identified slow cycling label retaining cells in nail and sweat gland appendages, showing stem cell characteristics similar to hair follicles but with distinct features.