Low-dose oral isotretinoin improved hair loss and facial bumps in patients with a specific type of hair loss.
6 citations,
February 2022 in “JAAD International” Higher doses of isotretinoin may lead to more hair loss.
6 citations,
August 2020 in “Clinical case reports” Isotretinoin was not effective in treating facial lichen planopilaris.
5 citations,
March 2021 in “International Journal of Dermatology” Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
5 citations,
July 2019 in “Journal of Cutaneous Medicine and Surgery” Isotretinoin may cause hair loss, especially in women and young adults.
4 citations,
December 2016 in “Journal of Pakistan Association of Dermatology” Using isotretinoin gel and minoxidil solution together effectively regrows hair in most people with patchy hair loss.
3 citations,
October 2019 in “CRC Press eBooks” Isotretinoin effectively treats severe acne but can cause significant side effects like dry skin and hair loss.
3 citations,
January 2015 in “Indian journal of paediatric dermatology” Oral isotretinoin temporarily improved skin symptoms in a child with IFAP syndrome.
2 citations,
January 2014 in “Advanced Biomedical Research” Oral isotretinoin and cyproterone compound are equally effective for treating acne in women with cutaneous hyperandrogenism.
1 citations,
December 2022 in “Archives of Dermatological Research” Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.
1 citations,
January 2021 in “Journal of dermatology & dermatologic surgery” Oral isotretinoin does not cause milia in acne patients.
1 citations,
March 2011 in “Informa Healthcare eBooks” Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.
1 citations,
March 1995 in “Pharmacoepidemiology and drug safety” Taking oral contraceptives while on isotretinoin may increase the risk of high triglyceride and cholesterol levels.
1 citations,
November 1987 in “Journal of The American Academy of Dermatology” Isotretinoin can raise CPK levels, so patients need monitoring, especially before surgery.
July 2024 in “JAAD Case Reports” Isotretinoin may effectively treat hereditary hypotrichosis simplex, a rare hair loss condition.
March 2024 in “Journal of cosmetic dermatology” Isotretinoin can effectively reduce symptoms of frontal fibrosing alopecia.
January 2024 in “Biological trace element research” Isotretinoin affects trace element levels and requires monitoring of liver and kidney functions.
August 2023 in “Dermatology Reports” Acne not improved by usual treatments may indicate a genetic disorder.
April 2023 in “Journal of Investigative Dermatology” Acne patients have higher skin mTORC1 activity, which is reduced by isotretinoin treatment.
December 2022 in “Research Square (Research Square)” Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
August 2022 in “Case reports” Isotretinoin effectively treated a rare scalp condition, but careful drug monitoring and a dairy-free diet were important.
May 2022 in “Research Square (Research Square)” Isotretinoin treatment increases p53 levels in the skin, which may explain its effectiveness against acne.
Isotretinoin may cause temporary, reversible facial hair growth in some women.
September 2021 in “Revista Interdisciplinar em Saúde” Oral isotretinoína effectively stabilizes frontal fibrosing alopecia.
September 2020 in “Journal of Education, Health and Sport” Most patients on isotretinoin for acne experience mild, dose-related side effects, but the connection to depression or bowel disease is uncertain.
March 2020 in “European Journal of Pediatric Dermatology” Isotretinoin can cause gynecomastia by lowering testosterone levels.
September 2019 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Isotretinoin at low doses effectively treats facial papules in frontal fibrosing alopecia.
Delonix polymeric nanoparticles with isotretinoin effectively treat acne by targeting hair follicles and reducing skin irritation.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Acne treatment, including isotretinoin, improves quality of life and does not worsen depression.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Low-dose isotretinoin is as effective as conventional doses for acne and has fewer side effects.